Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model

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Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma

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Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin

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Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors

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Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions

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The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis

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Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer

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Microenvironment drives cell state,plasticity, and drug response in pancreatic cancer

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The role of lipids in cancer progression and metastasis

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Discovering dominant tumor immune archetypes in a pan-cancer census

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Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche

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Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion

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Cellular architecture of human brain metastases

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Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells

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Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma

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Glioblastoma hijacks neuronal mechanisms for brain invasion

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A “spindle and thread” mechanism unblocks p53 translation by modulating N-terminal disorder

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Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids

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Reshaping of the tumor microenvironment by cellular senescence: An opportunity for senotherapies

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Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

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