共查询到4条相似文献,搜索用时 756 毫秒
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E. E. van der Wall 《Netherlands heart journal》2009,17(6):223-223
Recently, cardiologists have started serious debates over expensive medical technologies, questioning the conclusions that high-resolution cardiac CT images are almost as effective as conventional angiograms. This debate reveals a deep gap among cardiologists over the use of multi-slice CT angiography. A number of physicians have immediately embraced CT technology and installed expensive CT scanners in their hospitals in order to detect early signs of coronary artery disease. 相似文献
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Yu G Yamashita M Aoshima K Takahashi M Oshikawa T Takayanagi H Laurent S Burtea C Vander Elst L Muller RN 《Bioorganic & medicinal chemistry letters》2007,17(8):2246-2249
A new low-molecular weight dendrimer-like MRI contrast agent (Gd-D1) has been synthesized and characterized in vitro by proton and oxygen-17 relaxometry. Its pharmacokinetic parameters and biodistribution patterns were evaluated on rats. Its in vitro and in vivo properties, that is, the longitudinal relaxivity (defined as the increase of the water proton longitudinal relaxation rate induced by one millimole per liter of Gd-D1) equal to 5.6s(-1)mM(-1) at 20 MHz and 310 K, the elimination half-time equal to 85 min, and its low accumulation in liver and spleen, underline its potential as a blood-pool MRI contrast agent. 相似文献
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