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1.
Vedat Cinar Rasim Mogulkoc Abdulkerim Kasim Baltaci 《Biological trace element research》2010,134(2):130-135
In the present study, experiments were designed to investigate if supplementation with calcium during 4 weeks had an effect
on blood parameters in sedentary male athletes at rest and exhaustion. Thirty healthy subjects of ages ranging from 18 to
22 years were included in the study. The subjects were separated into three groups, as follows: Group 1 consisted sedentary
athletes receiving 35 mg/kg/day calcium gluconate. Group 2 included subjects equally supplemented with calcium training 90 min/day
for 5 days/week. Group 3 were subject to the same exercise regime but did not receive calcium supplements. Blood parameters
were determined in the experimental subjects at rest and after exhaustion. The leukocyte count (WBC) of athletes in groups
2 and 3 were significantly higher at exhaustion (p < 0.05). There were no significant differences in the WBC of the two supplemented groups. The erythrocyte count (RBC) was
increased in the supplemented athletes after training (p < 0.05), but hemoglobin, hematocrit, and trombocyte levels remained unchanged. The mean corpuscular volume increased in the
calcium-supplemented group at rest (p < 0.05). These results suggest that calcium supplementation only causes increases in white and red blood cell counts in athletes
after exhaustion while other hematological parameters remain unchanged. 相似文献
2.
Vedat Cinar Yahya Polat Abdulkerim Kasim Baltaci Rasim Mogulkoc 《Biological trace element research》2011,140(1):18-23
This study was performed to assess how 4 weeks of magnesium supplementation and exercise affect the free and total plasma
testosterone levels of sportsmen practicing tae kwon do and sedentary controls at rest and after exhaustion. The testosterone
levels were determined at four different periods: resting before supplementation, exhaustion before supplementation, resting
after supplementation, and exhaustion after supplementation in three study groups, which are as follows: Group 1—sedentary
controls supplemented with 10 mg magnesium per kilogram body weight. Group 2—tae kwon do athletes practicing 90–120 min/day
supplemented with 10 mg magnesium per kilogram body weight. Group 3—tae kwon do athletes practicing 90–120 min/day receiving
no magnesium supplements. The free plasma testosterone levels increased at exhaustion before and after supplementation compared
to resting levels. Exercise also increased testosterone levels relative to sedentary subjects. Similar increases were observed
for total testosterone. Our results show that supplementation with magnesium increases free and total testosterone values
in sedentary and in athletes. The increases are higher in those who exercise than in sedentary individuals. 相似文献
3.
Vedat Cinar Rasim Mogulkoc Abdulkerim Kasim Baltaci Ozgur Bostanci 《Biological trace element research》2010,133(1):29-33
This study was performed to determine how the calcium supplementation for a 4-week period affects the glucose and insulin
levels at rest and at exhaustion in athletes. This is a 4-week study performed on 30 healthy subjects varying between 18 and
22 ages. Subjects were separated into three groups: first group (group supplemented with calcium, sedentary group), second
group (calcium supplementations + exercise group), and third group (training group). Glucose and insulin parameters of the
groups were measured four times, at rest and exhaustion in the beginning of the research and at rest and exhaustion after
the end of 4 weeks application period. Exhaustion measurements both before and after the supplementations significantly decreased
in compared to rest measurements in terms of insulin (p < 0.05). Significant difference was not determined in the glucose values of groups. In terms of glucose, values increased
in all of the three groups occurred with exercise both before and after the supplementation by exercise and exhaustion (p < 0.05). The results of our study indicate that calcium gluconate supplementations for 4 weeks in sedentary subjects and
athletes did not significantly affect plasma insulin levels at rest and exhaustion. However, glucose levels were affected
by calcium supplementation and exhausting exercise in athletes. 相似文献
4.
The effects of magnesium supplementation on blood parameters were studied during a period of 4 wk in adult tae-kwon-do athletes
at rest and exhaustion. Thirty healthy subjects of ages ranging in age from 18 to 22 yr were included in the study. The subjects
were separated into three groups, as follows: Group 1 consisted of subjects who did not train receiving 10 mg/kg/d magnesium.
Group 2 included subjects equally supplemented with magnesium and exercising 90–120 min/d for 5 d/wk. Group 3 were subject
to the same exercise regime but did not receive magnesium supplements. The leukocyte count (WBC) was significantly higher
in groups 1 and 2 than in the subjects who did not receive any supplements (p < 0.05). There were no significant differences in the WBC of the two groups under magnesium supplementation. The erythrocyte,
hemoglobin, and trombocyte levels were significantly increased in all groups (p < 0.05), but the hematocrit levels did not show any differences between the groups although they were increased after supplementation
and exercise. These results suggest that magnesium supplementation positively influences the performance of training athletes
by increasing erythrocyte and hemoglobin levels. 相似文献
5.
The effects of magnesium supplementation on plasma magnesium, zinc, and copper levels were determined in young adult tae-kwon-do
athletes and sedentary controls at rest and exhaustion. After a 4-week supplementation period with 10 mg/day/kg Mg, the plasma
magnesium, copper, and zinc levels significantly increased in sedentary and training (90–120 min training 5 days a week) subjects
when compared to nonsupplemented controls (p < 0.05). 相似文献
6.
Fatih Kiyici Hüseyin Eroğlu N. Fazil Kishali Guleda Burmaoglu 《Biochemical genetics》2017,55(5-6):387-394
The purpose of this study was to examine the effects of Citrulline/Malate supplementation with intensive training on blood lactate level in active handball players. The athletes were subjected to intense training for 4 weeks, 4 days a week, mainly pre-season strength and technique training. In this training period, stimol group (n = 11) athletes were given stimol 3 times a day as 1 g for breakfast, 1 g for lunch, and 1 g for dinner while the placebo group (n = 11) athletes were given only placebo in the same dosage and the same color at the same time. Blood lactate levels in athletes were measured 4 times, prior to and after a 1-month program as follows: rest (R), end effort (EE), recuperation 5 min (R5 m), and recuperation 20 min (R20 m). Blood lactate levels were compared both as intra-group and between the groups. In intra-group comparison, no change was observed in blood lactate levels in placebo group while a significant difference was found in the levels of stimol group as p < 0.05 with a 49.8% decrease in blood lactate level. In the measurements between groups, in the post-test measurements made after the training period, significant differences as p < 0.05 were found with a 60.7% decrease in blood lactate level EE. Considerable decline was seen especially immediately after exercise in blood lactate levels of the athletes being given stimol supplement. In this case, we can say that Citrulline/Malate supplementation may contribute positively to the performance of athletes and may help postpone fatigue at excessive or prolonged activity. 相似文献
7.
The effects of a 1-month exercise program and magnesium supplementation on the adrenocorticotropic hormone and cortisol levels
were studied in young tae-kwon-do and sedentary subjects both at rest and exhaustion. The hormone levels were compared before
and after supplementation with 10 mg of magnesium (as magnesium sulfate) per kilogram of body weight. Both exercise and magnesium
supplements caused significant increases of the adrenocorticotropic hormone (p < 0.05). The cortisol levels were increased in training subjects receiving supplements (p < 0.05) but not so in subjects that either trained or received magnesium supplements in an independent manner. The cortisol
levels measured in resting individuals were higher in the supplemented and non-supplemented athletes than those in sedentary
subjects (p < 0.05). The results of this study show that exercise and/or magnesium supplementation causes a rise of the adrenocorticotropic
hormone, whereas cortisol is increased only as a result of combined exhaustion and magnesium supplements. 相似文献
8.
Cinar V 《Neuro endocrinology letters》2007,28(5):708-712
The effect of magnesium on thyroid hormones of sedentars and sportsperson in Tae-Kwon-Do, has been investigated in a 4-weeks training program. Group 1 consisted of sedentars receiving 10 mg/kg/day Mg for 4 weeks. Group 2 consisted of subjects receiving magnesium (Mg) supplement and practicing Tae-Kwon-Do for 90-120 min/day, for five days a week. Group 3 consisted of subjects practicing Tae-Kwon-Do but receiving Mg supplements. TSH levels increased with training and Mg supplementation (p<0.05). Mg increased FT3 values. (p<0.05). TT3 values of groups reduced in all groups (p<005). After supplementation, group 1 had higher TT4 values than groups 1 and 3 and the group 2 had higher TT4 values than the third group (p<005). Results of this research show that training until exhaustion causes reduction in thyroid hormone activity in sedentars and sportsperson. It has been established that Mg supplementation however, prevents reduction in thyroid hormone activity in sedentars and sportsperson. 相似文献
9.
This study was performed to assess how magnesium supplementation affects plasma lactate levels at rest and exhaustion in sportsmen and sedentary. Research was performed on 30 healthy subjects varying between 18-22 years of age for a four-week period. Subjects were separated into 3 groups: Group 1; sedentary taking magnesium supplementation only (10 mg/kg/day) (Mg + S), Group 2; subjects magnesium supplemented + training 90-120 min 5 days a week (Mg + Training), Group 3; training 90-120 min 5 days a week. Lactate levels of the groups were measured 4 times; at rest and exhaustion in the beginning of the research and after the end of the research. At the end of the research, exhaustion measurements both before and after supplement were found significantly higher than rest measurements in terms of lactate levels (p < 0.05). An important decrease was determined in the lactate levels of the 1st and 2nd groups when compared to their first measurements (p < 0.05). The results of this research indicate that lactate increases with exhaustion. However, magnesium supplement may positively affect performance of sportsmen by decreasing their lactate levels. 相似文献
10.
Yaira Barranco-Ruiz Antonio Martínez-Amat Cristina Casals Jerónimo Aragón-Vela Silvia Rosillo Silvana N. Gomes Ana Rivas-García Rafael Guisado Jesús R. Huertas 《Journal of physiology and biochemistry》2017,73(1):37-48
The effect of exercise-induced oxidative stress on health and aging is not clearly explained. This study examined the effects of habitual sport practice, age, and submaximal exercise on the blood markers of oxidative stress, muscle damage, and antioxidant response. Seventy-two healthy men were grouped by their habitual sport practice: inactive (<1.5 h/week), recreational (3–8 h/week), and trained athletes (>8 h/week), and further divided by age: young (18–25 years), adult (40–55 years), and senior (>55 years). Blood samples were collected at rest and after submaximal effort. Hydroperoxides and superoxide dismutase, glutathione peroxidase, and catalase activities were measured by spectrophotometry. Nuclear DNA damage was analyzed by comet assay. The alpha-actin release was analyzed by Western blot. Alpha-tocopherol, retinol, and coenzyme-Q10 were quantified by high-performance liquid chromatography analysis. Data was analyzed through a factorial ANOVA and the Bonferroni post hoc test. Lipid peroxidation increased significantly with age and submaximal effort (p?<?0.05). However, the trained athlete group presented lower lipid peroxidation compared with the recreational group (MD?=?2.079, SED?=?0.58, p?=?0.002) and inactive group (MD?=?1.979, SED?=?0.61, p?=?0.005). Trained athletes showed significant higher alpha-actin levels (p?<?0.001) than the other groups. Recreational group showed lower nuclear DNA damage than trained athletes (MD?=?3.681, SED?=?1.28, p?=?0.015). Nevertheless, the inactive group presented significantly higher superoxide dismutase and catalase (p?<?0.05) than the other groups. Data suggested that habitual competitive training practice could prevent age-related increases of plasma lipid peroxidation, which, according with our results, cannot be entirely attributed to blood antioxidant defense systems. 相似文献
11.
The present study was performed to investigate the effects of strenuous exercise and calcium supplementation on cortisol and
adrenocorticotropic hormone levels in athletes at rest and exhaustion. Thirty male athletes, ages 17–21 years, were enrolled
in the 4-week study. They were divided into three groups as follows: group 1 (n = 10): training without supplementation; group 2 (n = 10): training and calcium supplemented, and group 3 (n = 10): calcium supplemented without training. Venous blood samples were obtained for determination of the hormones. One-month
supplementation with calcium does not influence the cortisol and adrenocorticotropic hormone in athletes, but strenuous exercise
results in a significant increase in their levels with or without supplementation (p < 0.05). 相似文献
12.
Suleyman Patlar Ekrem Boyali Abdulkerim Kasim Baltaci Rasim Mogulkoc 《Biological trace element research》2011,139(3):296-300
The present study aims to examine the effects of both physical activity and vitamin A supplementation on trace element metabolism
in individuals engaged in taekwondo. The study registered seven healthy male national taekwondo players whose mean age was
21.86 ± 0.34 years and mean weight was 64.86 ± 2.72 kg. The subjects were supplemented with oral administration of 100 mg
vitamin A (retinol) for 6 weeks, and concurrently, they were subjected to taekwondo training 5 days a week. Before starting
the vitamin A supplementation, blood samples were taken from the subjects twice, once at rest and once after exhaustion. Similarly,
at the end of the 6-week vitamin A supplementation, two blood samples were taken from the subjects, once at rest and once
after exhaustion, in order to determine (by atomic emission) and compare serum cobalt, molybdenum, calcium, cadmium, chromium,
copper, manganese, sodium, nickel, phosphorus, sulfur, iron, boron, and zinc (mg/L) levels. Values of boron and nickel dropped
significantly after 6-week vitamin A supplementation (p < 0.001). Reduced levels of boron and nickel we obtained in the present study are believed to result from the antioxidant
effect of long-term vitamin A supplementation. 相似文献
13.
Gabriel Tobias Fabiana Braga Benatti Vitor de Salles Painelli Hamilton Roschel Bruno Gualano Craig Sale Roger C. Harris Antonio Herbert Lancha Jr. Guilherme Gianinni Artioli 《Amino acids》2013,45(2):309-317
We examined the isolated and combined effects of beta-alanine (BA) and sodium bicarbonate (SB) on high-intensity intermittent upper-body performance in judo and jiu-jitsu competitors. 37 athletes were assigned to one of four groups: (1) placebo (PL)+PL; (2) BA+PL; (3) PL+SB or (4) BA+SB. BA or dextrose (placebo) (6.4 g day?1) was ingested for 4 weeks and 500 mg kg?1 BM of SB or calcium carbonate (placebo) was ingested for 7 days during the 4th week. Before and after 4 weeks of supplementation, the athletes completed four 30-s upper-body Wingate tests, separated by 3 min. Blood lactate was determined at rest, immediately after and 5 min after the 4th exercise bout, with perceived exertion reported immediately after the 4th bout. BA and SB alone increased the total work done in +7 and 8 %, respectively. The co-ingestion resulted in an additive effect (+14 %, p < 0.05 vs. BA and SB alone). BA alone significantly improved mean power in the 2nd and 3rd bouts and tended to improve the 4th bout. SB alone significantly improved mean power in the 4th bout and tended to improve in the 2nd and 3rd bouts. BA+SB enhanced mean power in all four bouts. PL+PL did not elicit any alteration on mean and peak power. Post-exercise blood lactate increased with all treatments except with PL+PL. Only BA+SB resulted in lower ratings of perceived exertion (p = 0.05). Chronic BA and SB supplementation alone equally enhanced high-intensity intermittent upper-body performance in well-trained athletes. Combined BA and SB promoted a clear additive ergogenic effect. 相似文献
14.
The hematological effects of oral supplementation of zinc to training athletes are reported in the present study. A total
of 30 subjects between 16 and 22 yr of age volunteered to participate in a 4-wk study. They were equally divided into three
groups. Group 1 acted as resting controls receiving daily doses of 3 mg Zn/kg body wt. Group 2 was actively engaged in wrestling
and exercised for 90–120 min, 5 d a week. Group 3 was also actively engaged in wrestling and exercised for 90–120 min, 5 d
a week, but they were supplemented with 3 mg Zn/kg body wt per day. The erythrocyte, leukocyte, and thrombocyte counts and
the hemoglobin values of all subjects participating in the study were measured before and after exercise at the beginning
and at the end of the 4-wk study period.
In all groups, there were no significant differences in the measured parameters before and after exercise. At the end of the
supplementation period, the parameters of the subjects in groups 1 and 3 were significantly higher than those of group 2,
both before (p<0.005) and after (p<0.05) exercise. These results suggest that zinc supplementation has a positive effect on hematological parameters in athletes. 相似文献
15.
Xiao-hua Ren Ying-shui Yao Lian-ping He Yue-long Jin Wei-wei Chang Jie Li Yan Chen Xiu-li Song Hui Tang Ling-ling Ding Dao-xia Guo Chao-ping Li 《Biological trace element research》2013,156(1-3):74-78
Obesity is a risk of cardiovascular diseases. Our previous studies revealed that serum calcium level may have influence in the blood pressure to older male subjects. The aim of this study was to evaluate the relationship between total serum calcium level and overweight and obesity subjects. In our study, overweight and obesity status and total serum calcium level were measured among 2,503 subjects, at age range of 22–94 years, who were recruited for the routine health screening in 2006. The estimated mean for age (p?<?0.001), white blood cell count (p?=?0.037), hemoglobin concentration (p?<?0.001), red blood cell count (p?<?0.001), total serum calcium level (p?<?0.001), total cholesterol weight (p?<?0.001), HDL-cholesterol (p?<?0.001), LDL-cholesterol (p?<?0.001), and triglyceride (p?<?0.001) of overweight and obesity subjects were significantly higher than those of non-overweight subjects. The prevalence of overweight/obesity in subjects according to the log-transformed total serum calcium level quartiles was 16.3–30.5 %. The prevalence of overweight/obesity subjects showed trends that were significant according to the total serum calcium level quartiles (p?<?0.001). The odds ratios (ORs) and 95 % confidence intervals (CIs) for overweight/obesity of the second, third, and fourth quartiles compared to the lowest quartile were 1.407 (1.050–1.883), 1.543 (1.136–2.095), and 1.360 (0.995–1.859), respectively, after adjusting for sex and age (p?<?0.001). These findings suggest that a higher prevalence of adult overweight/obesity is weakly associated with higher total serum calcium level in the Chinese population. 相似文献
16.
Kenya Yuki Murat Dogru Yutaka Imamura Itaru Kimura Yuichiro Ohtake Kazuo Tsubota 《Biological trace element research》2009,129(1-3):1-8
The objective of this study was to investigate the relationship between preeclampsia and iodine levels and magnesium concentration in the blood of subjects in the northeast Anatolia region where iodine deficiency is common. Blood specimens were obtained from 24 preeclamptic and 16 healthy pregnant women. Iodine levels in blood were determined by the Foss method based on the Sandell–Kolthoff reaction. Serum protein-bound iodine (PBI) levels and magnesium concentration in maternal blood were lower in patients with severe preeclampsia compared to normal pregnant women (8.46?±?1.22 vs. 11.46?±?1.71 μg/dL, p?<?0.001, 1.63?±?0.05 vs. 1.86?±?0.05 mg/dL, p?<?0.001, respectively). Serum PBI levels and magnesium concentration in umbilical cord blood were higher in patients with severe preeclampsia than in normal pregnant women (8.84?±?1.9 vs. 7.33?±?1.07 μg/dL, p?<?0.05, 2.48?±?0.03 vs. 2.02?±?0.01 mg/dL, p?<?0.001, respectively). There was a positive correlation between the serum PBI levels in maternal blood and magnesium concentration in maternal blood in patients with severe preeclampsia (r?=?0.41, p?<?0.05). Thus, iodine may be one factor contributing to the pathophysiology of preeclampsia. Iodine supplementation may be effective therapy in preeclamptic in pregnant women. 相似文献
17.
Fusun Sunar Zulfikare Isik Gormus Abdulkerim Kasim Baltaci Rasim Mogulkoc 《Biological trace element research》2008,126(1):11-14
The objective of the present study is to investigate how low-dose zinc supplementation for 2 weeks in the post-menopausal period influences levels of estrogen and progesterone in the serum. The study registered 32 natural menopause patients, who were allocated to four groups with equal number of patients. Group 1, control group, which was not subjected to any procedure. Group 2, the group that was supplemented with 15 mg/day zinc sulfate for 2 weeks. Group 3, the group that was given hormone replacement therapy (0.625 mg estrogen?+?5 mg medroxyprogesterone acetate/day) for 2 weeks. Group 4, the group that received hormone replacement therapy (0.625 mg estrogen?+?5 mg medroxyprogesterone acetate/day) and zinc sulfate (15 mg/day) for 2 weeks. Blood samples were collected twice from each subject, once at the beginning of the study, and once at the end of the 4-week procedure to determine estrogen (E2) and progesterone levels. Variance analysis was employed in the statistical evaluation of data. Level of significance was set at p?<?0.05. No significant difference was found between the estrogen and progesterone levels of groups 1 and 2. Groups 3 and 4 had higher estrogen and progesterone levels than groups 1 and 2 (p?<?0.05). Estrogen and progesterone levels in groups 3 and 4 were not different. Results of the study show that low-dose zinc supplementation to post-menopausal women for 2 weeks does not have a significant effect on the concerned parameters. 相似文献
18.
Andrée-Anne Clément Eléonor Riesco Sébastien Tessier Michel Lacaille Francine Pérusse Mélanie Coté Jean-Pierre Després John Weisnagel Jean Doré Denis R. Joanisse Pascale Mauriège 《Journal of physiology and biochemistry》2018,74(4):591-601
The contribution of adiposopathy to glucose-insulin homeostasis remains unclear. This longitudinal study examined the potential relationship between the adiponectin/leptin ratio (A/L, a marker of adiposopathy) and insulin resistance (IR: homeostasis model assessment (HOMA)), insulin sensitivity (IS: Matsuda), and insulin response to an oral glucose tolerance test before and after a 16-week walking program, in 29 physically inactive pre- and postmenopausal women with obesity (BMI, 29–35 kg/m2; age, 47–54 years). Anthropometry, body composition, VO2max, and fasting lipid-lipoprotein and inflammatory profiles were assessed. A/L was unchanged after training (p =?0.15), despite decreased leptin levels (p <?0.05). While the Matsuda index tended to increase (p =?0.07), HOMA decreased (p <?0.05) and fasting insulin was reduced (p <?0.01) but insulin area under the curve (AUC) remained unchanged (p =?0.18) after training. Body fatness and VO2max were improved (p <?0.05) while triacylglycerols increased and HDL-CHOL levels decreased after training (p <?0.05). At baseline, A/L was positively associated with VO2max, HDL-CHOL levels, and Matsuda (0.37?< ρ <?0.56; p <?0.05) but negatively with body fatness, HOMA, insulin AUC, IL-6, and hs-CRP levels (??0.41?< ρ <???0.66; p <?0.05). After training, associations with fitness, HOMA, and inflammation were lost. Multiple regression analysis revealed A/L as an independent predictor of IR and IS, before training (partial R2 =?0.10 and 0.22), although A/L did not predict the insulin AUC pre- or post-intervention. A significant correlation was found between training-induced changes to A/L and IS (r =?0.38; p <?0.05) but not with IR or insulin AUC. Although changes in the A/L ratio could not explain improvements to glucose-insulin homeostasis indices following training, a relationship with insulin sensitivity was revealed in healthy women with obesity. 相似文献
19.
Vitor de Salles Painelli Bryan Saunders Craig Sale Roger Charles Harris Marina Yázigi Solis Hamilton Roschel Bruno Gualano Guilherme Giannini Artioli Antonio Herbert Lancha Jr. 《Amino acids》2014,46(5):1207-1215
Recent investigations have suggested that highly trained athletes may be less responsive to the ergogenic effects of β-alanine (BA) supplementation than recreationally active individuals due to their elevated muscle buffering capacity. We investigated whether training status influences the effect of BA on repeated Wingate performance. Forty young males were divided into two groups according to their training status (trained: T, and non-trained: NT cyclists) and were randomly allocated to BA and a dextrose-based placebo (PL) groups, providing four experimental conditions: NTPL, NTBA, TPL, TBA. BA (6.4 g day?1) or PL was ingested for 4 weeks, with participants completing four 30-s lower-body Wingate bouts, separated by 3 min, before and after supplementation. Total work done was significantly increased following supplementation in both NTBA (p = 0.03) and TBA (p = 0.002), and it was significantly reduced in NTPL (p = 0.03) with no difference for TPL (p = 0.73). BA supplementation increased mean power output (MPO) in bout 4 for the NTBA group (p = 0.0004) and in bouts 1, 2 and 4 for the TBA group (p ≤ 0.05). No differences were observed in MPO for NTPL and TPL. BA supplementation was effective at improving repeated high-intensity cycling performance in both trained and non-trained individuals, highlighting the efficacy of BA as an ergogenic aid for high-intensity exercise regardless of the training status of the individual. 相似文献
20.
Nurhan Gumral Mustafa Naziroglu Ahmet Koyu Kurtulus Ongel Omer Celik Mustafa Saygin Mesud Kahriman Sadettin Caliskan Mustafa Kayan Osman Gencel Manuel F. Flores-Arce 《Biological trace element research》2009,132(1-3):153-163
The levels of blood lipid peroxidation, glutathione peroxidase, reduced glutathione, and vitamin C were used to follow the level of oxidative damage caused by 2.45 GHz electromagnetic radiation in rats. The possible protective effects of selenium and L-carnitine were also tested and compared to untreated controls. Thirty male Wistar Albino rats were equally divided into five groups, namely Groups A1 and A2: controls and sham controls, respectively; Group B: EMR; Group C: EMR + selenium, Group D: EMR + L-carnitine. Groups B–D were exposed to 2.45 GHz electromagnetic radiation during 60 min/day for 28 days. The lipid peroxidation levels in plasma and erythrocytes were significantly higher in group B than in groups A1 and A2 (p?<?0.05), although the reduced glutathione and glutathione peroxidase values were slightly lower in erythrocytes of group B compared to groups A1 and A2. The plasma lipid peroxidation level in group A2 was significantly lower than in group B (p?<?0.05). Erythrocyte reduced glutathione levels (p?<?0.01) in group B; erythrocyte glutathione peroxidase activity in group A2 (p?<?0.05), group B (p?<?0.001), and group C (p?<?0.05) were found to be lower than in group D. In conclusion, 2.45 GHz electromagnetic radiation caused oxidative stress in blood of rat. L-carnitine seems to have protective effects on the 2.45-GHz-induced blood toxicity by inhibiting free radical supporting antioxidant redox system although selenium has no effect on the investigated values. 相似文献