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Common logic of transcription factor and microRNA action 总被引:12,自引:0,他引:12
Hobert O 《Trends in biochemical sciences》2004,29(9):462-468
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Ali Noman Shah Fahad Muhammad Aqeel Usman Ali Amanullah Sumera Anwar Shahbaz Khan Baloch Madiha Zainab 《Biotechnology letters》2017,39(5):685-700
Cumulatively, biotic and abiotic stresses of various magnitudes can decrease the production of crops by 70%. miRNAs have emerged as a genetic tool with enormous potential that can be exploited to understand stress tolerance at the molecular level and eventually regulate stress in crops. Plant miRNA targets frequently fit into diverse families of TFs that control the expression of genes related to a certain trait. As key machinery in gene regulatory networks, it is agreed that a broad understanding of miRNAs will greatly increase our understanding of plant responses to environmental stresses. miRNA-led stress regulatory networks are being considered as novel tools for the development of abiotic stress tolerance in crops. At this time, we need to expand our knowledge about the modulatory role of miRNAs during environmental fluctuations. It has become exceedingly clear that with increased understanding of the role of miRNAs during stress, the techniques for using miRNA-mediated gene regulation to enhance plant stress tolerance will become more effective and reliable. In this review we present: (1) miRNAs as a potential avenue for the modulation of abiotic stresses, and (2) summarize the research progress regarding plant responses to stress. Current progress is explained through discussion of the identification and validation of several miRNAs that enhance crop tolerance of salinity, drought, etc., while missing links on different aspects of miRNAs related to abiotic stress tolerance are noted. 相似文献
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An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription 总被引:1,自引:0,他引:1
Knouf EC Garg K Arroyo JD Correa Y Sarkar D Parkin RK Wurz K O'Briant KC Godwin AK Urban ND Ruzzo WL Gentleman R Drescher CW Swisher EM Tewari M 《Nucleic acids research》2012,40(2):499-510
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