共查询到20条相似文献,搜索用时 31 毫秒
1.
Mitochondrial dynamics: quantifying mitochondrial fusion <Emphasis Type="Italic">in vitro</Emphasis>
Mitochondrial fusion is an essential process for preserving the integrity and stability of mitochondrial DNA; however, regulation
of this process remains largely mysterious. In this issue of BMC Biology, Schauss and colleagues describe a simple, reliable, and robust novel assay that allows fusion of mammalian mitochondria
to be quantified in vitro. 相似文献
2.
BMC Systems Biology is the first open access journal spanning the growing field of systems biology from molecules up to ecosystems. The journal
has launched as more and more institutes are founded that are similarly dedicated to this new approach. BMC Systems Biology builds on the ongoing success of the BMC series, providing a venue for all sound research in the systems-level analysis of biology. 相似文献
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The expansion of genome sequencing projects has produced accumulating evidence for lateral transfer of genes between prokaryotic
and eukaryotic genomes. However, it remains controversial whether these genes are of functional importance in their recipient
host. Nikoh and Nakabachi, in a recent paper in BMC Biology, take a first step and show that two genes of bacterial origin are highly expressed in the pea aphid Acyrthosiphon pisum. Active gene expression of transferred genes is supported by three other recent studies. Future studies should reveal whether
functional proteins are produced and whether and how these are targeted to the appropriate compartment. We argue that the
transfer of genes between host and symbiont may occasionally be of great evolutionary importance, particularly in the evolution
of the symbiotic interaction itself. 相似文献
5.
Several recent papers, including one in BMC Evolutionary Biology, examine the colonization history of house mice. As well as background for the analysis of mouse adaptation, such studies
offer a perspective on the history of movements of the humans that accidentally transported the mice. 相似文献
6.
C Robertson McClung 《BMC biology》2010,8(1):55
The circadian clock enhances fitness through temporal organization of plant gene expression, metabolism and physiology. Two
recent studies, one in BMC Evolutionary Biology, demonstrate through phylogenetic analysis of the CCA1/LHY and TOC1/PRR gene families that the common ancestor of monocots and eudicots had components sufficient to construct a circadian clock
consisting of multiple interlocked feedback loops. 相似文献
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The majority of convincingly documented cases of hybridization in angiosperms has involved genetic introgression between the
parental species or formation of a hybrid species with increased ploidy; however, homoploid (diploid) hybridization may be
just as common. Recent studies, including one in BMC Evolutionary Biology, show that pollinator shifts can play a role in both mechanisms of hybrid speciation. 相似文献
9.
Geoffrey Ian McFadden 《BMC biology》2018,16(1):140
The capture and enslavement of eukaryotic algae by unicellular predators to acquire photosynthesis was a major driving force in early eukaryotic diversification. A genome presented in BMC Biology provides a glimpse of how such a tiny predator might have preyed on red algae and detained them to create new lineages of photosynthetic organisms. 相似文献
10.
Karen G Hales 《BMC biology》2010,8(1):79
A recent paper in BMC Developmental Biology reports that a mitochondrial iron importer is required for Drosophila male fertility and normal mitochondrial shaping in spermatids. This suggests that mitochondrial morphogenesis during insect
spermatogenesis may be a useful new context in which to study iron metabolism. 相似文献
11.
Genome-wide association studies (GWAS) look for correlations between traits of interest and genetic markers spread throughout
the genome. A recent study in BMC Genetics has found that populations of the malaria parasite Plasmodium vivax should be amenable to GWAS searching for a genetic basis of parasite pathogenicity. Geographical substructure in populations
may, however, prove a problem in interpreting the results. 相似文献
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This paper is a response to Gray MM, Sutter NB, Ostrander EA, Wayne RK: The IGF1 small dog haplotype is derived from Middle Eastern grey wolves. BMC Biology 2010, 8:16. 相似文献
14.
Whilst parthenogenesis has evolved multiple times from sexual invertebrate and vertebrate lineages, the drivers and consequences
of the sex-asex transition remain mostly uncertain. A model by Stouthamer et al. recently published in BMC Evolutionary Biology shows a pathway by which obligate asexuality could be selected for following endosymbiont infection. 相似文献
15.
Peter A Brennan 《BMC biology》2010,8(1):71
A study in the current issue of BMC Biology has identified a mouse major urinary protein as a pheromone that attracts female mice to male urine marks and induces a learned
attraction to the volatile urinary odor of the producer. See research article 相似文献
16.
The Hedgehog (Hh) signaling pathway differentially utilizes the primary cilium in mammals and fruit flies. Recent work, including
a study in BMC Biology, demonstrates that Hh signals through the cilium in zebrafish, clarifying the evolution of Hh signal transduction. 相似文献
17.
Eric W Schmidt 《BMC biology》2010,8(1):83
A recent report in BMC Biology on the discovery and analysis of biosynthetic genes for ribosomal peptide natural products confirms that these pathways are
much more common and diverse than previously suspected, contributing substantially to the chemical arsenal employed by bacteria. 相似文献
18.
Molecular interaction networks provide a window on the workings of the cell. However, combining various types of networks
into one coherent large-scale dynamic model remains a formidable challenge. A recent paper in BMC Systems Biology describes a promising step in this direction. 相似文献
19.
Robert A Cross 《BMC biology》2010,8(1):107
Kinesin-14 motor proteins step towards microtubule minus ends, in the opposite direction to other kinesins. Work on the still-enigmatic
kinesin-14 mechanism published in BMC Structural Biology shows that the carboxyl terminus of the motor head undergoes a dock-undock cycle, like that of plus-end-directed kinesins. 相似文献
20.
The nuclear factor CTCF has been shown to be necessary for the maintenance of genetic imprinting at the mammalian H19/Igf2
locus. MacDonald and colleagues now report in BMC Biology that the mechanisms responsible for maintaining the imprinted state in Drosophila may be evolutionarily conserved and that CTCF may also play a critical role in this process. 相似文献