共查询到20条相似文献,搜索用时 31 毫秒
1.
2.
Thymic peptide thymosin 1 (10–9 to 3 x 1010–7 M) is shown to inhibit the specific binding of [125I]VIP to rat blood mononuclear cells and liver plasma membranes. Thymosin 1 was 160 and 6250 times less potent that VIP at inhibiting [125I]VIP binding to blood mononuclear cells and liver plasma membranes, respectively. Thymosin 1 (10–10 to 1010–7 M) was weak in stimulating adenylate cyclase activity. Its efficacy is about 25 % and 27 % that of native VIP in blood mononuclear cells and liver plasma membranes, respectively. Thymosin 1 may behave as a partial VIP agonist in rat.Abbreviations GRF
growth hormone releasing factor
- PHI
porcine intestinal peptide having N-terminal histidine and C-terminal isoleucine amide
- GIP
gastric inhibitory polypeptide
- VIP
vasoactive intestinal peptide 相似文献
3.
肽核酸(peptide nucleic acid,PNA)阵列 总被引:1,自引:0,他引:1
肽核酸(PNA)以N—(2—氨基乙基)甘氨酸替代DNA分子中的磷酸戊糖骨架。它能特异性地识别与DNA、RNA所形成的杂交体。PNA—DNA、PNA—RNA的热稳定性要比相应的DNA—DNA、DNA—RNA高,而且PNA识别单碱基的能力强于DNA和RNA,使之在微阵列,尤其是SNP检测领域有着广泛的应用前景。本文简述了PNA阵列从探针设计、阵列合成、杂交和检测的全过程。 相似文献