共查询到20条相似文献,搜索用时 46 毫秒
1.
TheApproachandApplicationofGeneTargetingWANGYa-PingZHUZuo-Yan(InstituteofHydrobiology,TheChineseAcademyofSciences,Wuhan430072... 相似文献
2.
Pollengrainscausesomerespiratorysystemdiseasessuchasallergicasthmaandhayfever .Thesediseasesap pearespeciallyinfloweringperiodsof 相似文献
3.
The Expression of Nerve Growth Factor Receptor on Schwann Cells and the Effect of These Cells on Regeneration of Axons in Tra... 相似文献
4.
小麦醇溶蛋白盒结合因子基因启动子序列 总被引:2,自引:0,他引:2
1 Source Thesequencewasdeterminedfromare versePCRproduct,whichwasligatedtopMD1 8 Tvector(TaKaRaBiotechnologyCo .) ,fromnucleargenomicD 相似文献
5.
1 Source ThesequenceoftheatpBgenewasdeter minedfromPCRproductofchloroplastgenomicDNAofPopulustomentosa .2 Nameanddescription ThecodonsequenceoftheatpBgeneofPopulustomentosais 1 497nucleotidelongthatencodes 498aminoacidsofATPasebetasubunitofchloroplast.ItsDNA… 相似文献
6.
Auxinisatypeofplanthormoneexistingextensively[1].Itregulatesmanyprocessesinplantdevelopment[2,3].Accordingtothe“acidgrowththeory”,auxinstimulatesaseriesofreactionandthenpromotescellgrowthbybindingtheABPlocatedincellmembrane[4,5].Thestudiesontobaccomutantexhi… 相似文献
7.
Zhang Chunzhi Jin Fengxie Hisao Ohtake ** Kiyoshi TodaInstitute of Applied Microbiology of the University of Tokyo Department of Food Science Biotechnology Dalian College of Light Industry Baoding-Jie No. Zhongshan-Qu Dalian P. 《中国微生态学杂志》1999,(6)
Celluloseisthemostabundantnaturalbiopolymer.Howtoutilizeorhydrolyseitisaveryimportantprob-leminthefieldofbiotechnology.Sixstrains(JT)ofthermophilicanaerobicandcellulyticbacteriawereiso-latedfromcamelfeces,compost,soilandhotspringwa-terinJapan.Thesest… 相似文献
8.
TheenvelopeproteinofhepatitisBvirus(HBV)consistsofthreeproteins:small(S),middle(M)andlarge(L)[1].TheSproteincarriesalltheinformationrequiredforcellularlipidsmobilization,subviralparticleformationandsecretion.Ithasbeensuccessfullydevelopedasacarriertoexpressf… 相似文献
9.
植物染色体显微切割技术的研究现状与展望 总被引:10,自引:0,他引:10
植物染色体显微切割技术的研究现状与展望马有志徐琼芳辛志勇(中国农业科学院作物育种栽培研究所,北京100081)TheAdvancesoftheTechniqueofPlantChromosomeMicrodisectionMaYouzhiXuQion... 相似文献
10.
Anincreasingnumberofhomeoticgenescontrollingplantflowerdevelopmenthasbeenclonedinrecentyears.Thesestudieshavebeenfacilitatingourunderstandingofmolecularmechanismofplantdevelopment[1].Ithasbeenknownthatdifferenttypesofgenesareinvolvedininflorescencemeri… 相似文献
11.
A N Talalaenko I I Abramets Iu V Stakhovski? A A Shekhovtsov S L Shevchenko A V Chernikov 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1992,42(1):144-151
In experiments on rats the presence or absence was studied of the phenomenon of potentiation of anxiolytic action, estimated by the time of the animal stay in the light part of the chamber in tests of avoidance of "the lighted ground" or "menacing situation" at combined application of the pairs of substances of benzodiasepine and non-benzodiasepine series (elenium, indoter, campiron and campironin). Spectra of their neurochemical activity were determined in experiments on neurones of isolated spinal ganglia of rats with intracellular biopotentials records. It has been established that GABA-potentiating action of indoter and elenium, dopamine-negative action of campiron and campironin are significant in their anxiolytic action in the states of alarm of aversive genesis of different modalities. Serotoninmimetic effect of non-diasepine tranquilizers is of functional significance in the test of avoidance of "the lighted ground", but not of the "menacing situation". It is suggested that differences of neurochemical mechanisms of anxiolytic action of the tested tranquilizers testify to different neurochemical profiles of the neuronal "matrices" of the studied states of alarm. 相似文献
12.
E. A. Tsvetkov I. S. Masalov N. P. Vesselkin 《Journal of Evolutionary Biochemistry and Physiology》2009,45(4):490-500
The work deals with study of role of inhibitory interneurons in the process of regulation of sensory currents converging on
soma of pyramidal cells of the dorsolateral amygdala nucleus as well as of role of these interneurons in mechanism of regulation
of plasticity of amygdala synapses. It has been shown that the part of the spontaneous inhibitory postsynaptic currents recorded
on the dorsolateral amygdala pyramidal cells is relatively high and amounts to about a half of the total amount of the recorded
events. Analysis of the evoked postsynaptic responses has shown the interneurons to regulate activity and duration of these
responses due to the postsynaptic membrane hyperpolarization as a result of activation of GABAA-receptors. Also studied was role of interneurons in providing mechanisms of the long-term potentiation of the synaptic responses
evoked by stimulation of cortical and thalamic inputs. Block of effect of interneurons with help of picrotoxin has been shown
to lead to an increase of evoked potentiation of synaptic responses. 相似文献
13.
I N Knipst 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1991,41(6):1204-1214
Interhemispheric asymmetry was studied of spatial-temporal potentials organization (STPO) of the cortex in non-fixated animals in the states of deep rest, behavioural activity and in the transition period between them. Despite the intrahemispheric differences of the STPO in each of these states, interhemispheric divergences in the character of reconstructions of momentary topograms of the cortical potentials, recorded at 24-channels leading, are limited by 35% of the epoch analysis time. Comparison of the dynamics of intrahemispheric changes of topograms of cortical potentials in the left and right hemispheres in the states of rest and activity revealed a narrowing of temporal period of the absence of resemblance in reconstructions of successive topograms of the left and right hemispheres in comparison with transition processes. In the phase of rest the interhemispheric conjugation of spatial reconstructions in topograms became lowered mainly because of the disturbances of monotony of changes of their reliefs in one of the hemispheres in turn. In the active phase, deviations from STPO of the cortex, characteristic of the state of rest, were met more frequently in the right hemisphere; in that case oscillations of the topograms general mean level connected with the activity of non-specific activating subcortical brain system acquired a significant role in regulation of interhemispheric relations. Presence of interhemispheric resemblance of reconstructions of topograms reliefs in the active phase, despite the tendency to its lowering in comparison with the rest, testifies to the contribution also of the intracortical processes to the interhemispheric spatial synchronization of the cortical potentials in this state. 相似文献
14.
K Lupa Z Gieroba G Wójcik A Niechaj 《Archives internationales de physiologie et de biochimie》1986,94(2):91-98
Stimulation of either A- or C-fibres in the aortic nerve inhibits sympathetic nerve discharge (SND) recorded from the renal nerve in rabbits anaesthetized with urethane. When the test inhibition of SND to stimulation of A-fibres is preceded by conditioning stimulation of the same afferents, the test response is depressed at shorter and facilitated at longer testing intervals. Facilitation of the inhibition of SND reaches 120% of control at a testing interval of 10 s. The recovery curve of inhibition of SND to activation of A-fibres has a time course of 17 s. Following conditioning activation only depression of the test inhibition of SND to stimulation of C-fibres is seen. It reaches 46% of control at an interval of 2 s and the recovery curve of inhibition of SND to stimulation of C-fibres has a time course of about 30 s. In other series of experiments the duration of the conditioning stimulation was varied while the testing intervals were fixed. At a testing interval of 2 s the reductions of the test responses are deeper and the durations of conditioning at which plateaus of depression are reached are longer with stimulation of C- than of A-fibres. Taken together with a longer recovery curve these findings suggest a more effective control of the test inhibition of SND by C-fibres. Opposite changes in the patterns of inhibition of SND to activation of either A- or C-fibres are explained by frequency-dependent post-tetanic effects of the conditioning stimulation. 相似文献
15.
N E Sviderskaia T A Korol'kova G V Selitski? 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1990,40(5):934-943
In the present study the influence of the level of consciousness on spatial organization of the cortical functional activity in human psychic processes was investigated. For regulation of the level of consciousness models were used of hypnotic analgesia, automatization of intellectual actions and mental activity in hypnotic state. Evaluation of the mosaic of the cortical activity was made by parameters of spatial synchronization of the potentials with topographic mapping of crosscorrelation, spectral and coherent-phasic EEG characteristics. The obtained data allow to conclude about special role of the frontal areas of the left hemisphere in the process of realization of information. It has been shown that one of the main functions in neurophysiological structure of consciousness is the selection of signals according to dominating motivation. The frontal areas of the left hemisphere control the degree of inclusion of foci of increased activity, specific and non-specific for each type of activity, and possibly, regulate the way of transformation of the information. 相似文献
16.
A T Astvatsatur'yan Y M Ostrovskii E K Alimova F S Larin Z I Shilova I M Staviskii V U Buko 《Biology bulletin of the Academy of Sciences of the USSR》1979,6(5):643-645
Incubation of tissue of homogenates of peripheral nerves, liver, and subcutaneous adipose tissue of rabbits with [1-14C]palmitic acid and intraperitoneal injection of this preparation into rats, in a dose of 20 muCi per 100 g of weight of the animals, permitted establishment of the presence of enzyme systems of biosynthesis of n-alkanes in the tissues of higher animals. Evidence of the biosynthesis of n-alkanes in the animal organism represents a new aspect of our knowledge of the metabolism of this class of compounds in animal tissues. 相似文献
17.
N K Nagradova 《Biokhimii?a (Moscow, Russia)》1977,42(3):379-395
The structure of the active center of glyceraldehyde-3-phosphate dehydrogenase and the arrangement of subunits in the tetrameric molecule is delineated. The mechanism of cooperative effects in the oligomer is considered, and the involvement of various regions of the active center and of different-subunit contact area in the realization of the cooperative phenomena is discussed. A special attention is paid to the effect of NAD+ bound to one of the subunits of the tetramer on the structure of an adjacent subunit and to the problem of the participation of the coenzyme in the creation of anion-binding sites of the enzyme. The conditions of reversible dissociation of the tetrameric apoenzyme molecule into dimers are depicted, and the role of NAD+ in the organization of the quaternary structure of the dehydrogenase is discussed. The problem of catalytic activity of the dimeric form of the enzyme is argued. 相似文献
18.
The interferons (IFN's) are natural regulators of the immune response. This quality of IFN depends to a large extent on their capacity to change the expression of the antigens of the second (II) class of the Major Histocompatibility Complex. The most effective modulator of the expression of the antigens of the class II MHC is beta-IFN. The aim of this work is to explore with the aid of enzyme-linked immunosorbent assay (ELISA) peculiarities of an action of the preparations alpha- and beta-IFN's of a man on the expression of the antigens of the second class on macrophages of mice with using monoclonal antibodies to the products of subregions I-A and I-E MHC. As a result of exploration we have the following: both preparations IFN's (leukinterferon and beta-IFN) reinforce the expression of the antigens of the second class on the macrophages of mice spleens. With combined influence preparation alpha-IFN and beta-IFN show interweakened effect on the expression of the antigens of the class MHC. Exposed regularities of the expression have the same type for products of subregions I-A and I-E H-2 of mice complex. ELISA is the sensible method of determination of a level of the expression of the antigens of the class II MHC on the cell's populations. 相似文献
19.
V A Zosimovski? 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1986,36(1):170-175
Changes of cross-correlation histograms (CCH) of impulse trains and of mean interspike intervals (ISI) of neurones N1 and N2 with a common monosynaptic excitatory or inhibitory-excitatory input from N3, at changes of efficiency of interneuronal connections, neurone excitability and summate action on them of independent random afferent synaptic inflows were studied by methods of mathematical and biomathematical modelling of neuronal interaction. It was shown that the increase of amplitude of the central peak (trough) of a normalized CCH of N1-N2 accompanied by reduction of mean ISI of N1 and N2, is either a sign of an increase of the amplitude of postsynaptic potentials of N1 and N2 elicited by impulses of the nonrecorded N3 or a sign of an increase of mean ISI of N3. 相似文献