国际药理学术会议消息

第五届东南亚与西太平洋地区药理学术会议(5th Southeast Asian and Western Pacific RegionalMeeting of Pharmacologists,简称5th SEA/WP RMP)将于1988年7月4～8日在北京举行,国内外代表约600人左右。这是一次国际药理学术盛会。会议将进行药理学术交流(议程有:大会报告、小组论     

第五届东南亚西太平洋地区药理学家会议简讯

第五届东南亚西太平洋地区药理学家会议(5th Southeast Asian and Western Pacific Regional Meeting of Pharmacologists,5th SEA/WP RMP)于1988年7月4～8日在北京举行。来自30个国家和地区的近千名代表报告了他们的最新科研成果。大会共采纳了1003篇论文,分12个专题以各种形式进行交流。各专題论文数分配如下:神经药理104、心血管药理213、抗肿瘤药理30、毒理与药物评价41、临床药理91、药物代谢及药代动力学63、抗炎免疫药理111、天然药与传统药103、激素药理28、受体64、化疗49、方法学及分析技术12,其他以及未分     

国际会议消息

由国际植物物种生物学家组织(IOPB)主办的“第5届国际植物物种生物学学术讨论会(The 5th International Symposium of Plant Biosystematics)将于1992年在美国密苏里植物园召开。欲知详细情况可与彼得·雷文教授联系:     

大熊猫初乳免疫球蛋白含量及其动态变化

This paper first reports that the contents of slgA, IgC and IgM of 3 giant pandas'colostrums from day 1 to day 14 unconsecutively which have been determined by the method of “A Rate Nephelometer for Measuring Specific Protein by Immunopmciptin Reaction”. The results indicated that slgA is the most important immunuoglobulins of giant panda's colostmms, and IgG, IgM are also the major components of giant panda's colostrums. The contents of immunoglobulins in colostrums of giant pandas vary with the day : 1) the content of colostral sIgA is in the highest level (1 442.93 mg/dl) in 1st day, and maintains a higher level (1 200- 1 300 mg/dl) from 2nd day to 5th day, it drops abruptly in 7th day (727.61 mg/dl) ; 2) the content of colostral IgG is in the hingest level (861.5 mg/dl), and maintains in a higher level(648.74- 707.07 mg/dl) from 2nd day to 5th day, but drops abruptly in 7th day (375.14 mg/dl) ; 3) the content of colostral tgM varies rarely and maintains in a stable level during the first postpartum 5 days, and drops abruptly in 7th day . Based on the changes of immtmoglobulins in giant panda's milks, the author conclude that milks from 1st day to 5th day postpartum should be giant panda's colostrums.     

肌球蛋白单克隆抗体标记大鼠心肌坏死的研究

Monoclonal antibody (MAb) attained from hybridoma 1A5 was against human cardiac myosin heavy chains (CMHC) and didn't react with smooth muscle. It was labeled with Na 125 I and injected to the rats suffered from acute myocardial necrosis, which were treated by isoproylarterenol. After injection, the rats were studied from the 4 th to the 48 th hours by relative radioactivity in blood, thyroid gland, stomach, liver, lung, muscle and heart, respectively. The results indicated that 125 I CMHC MAb could specifically reach the target necrotic organ in the 4 th hours (2 03±0 60 ) and remained up to the 48 th hours (2 55±0 49) or longer, at which the 8 th was higher (4 89±0 44). Meanwhile 125 I CMHC MAb showed much higher affinity to necrotic cardiac tissue than the normal ( P <0 001). The same results were should in the blood from 4 th (4 94±0 45) to 48 th (2 70±0 12). Thus 125 I CMHC MAb can be considered as an effective tool for image diagnosis of acute myocardial necrosis.     

Phase Ⅰ/Ⅱ randomized controlled trial of autologous bone marrow-derived mesenchymal stem cell therapy for chronic stroke

AIM To examine the safety and efficacy of mesenchymal stem cell(MSC) therapy for intracerebral haemorrhage with neurological dysfunctions for a year.METHODS MSC were ex vivo expanded from 29 mL(17-42 mL) autologous bone marrow. Patients were randomized to have two intravenous injections of autologous MSC or placebos in four weeks apart. Neurological functions and clinical outcomes were monitored before treatment and at 12~(th), 16~(th), 24~(th), 36~(th) and 60~(th) week upon completion of~(th)e treatment. RESULTS A mean of 4.57 × 10~7(range: 1.43 × 10~7-8.40 × 10~7) MSC per infusion was administered accounting to 8.54 × 10~5(2.65 × 10~5-1.45 × 10~6) per kilogram body weight in two occasions. There was neither adverse event at time of administration nor sign of de novo tumour development among patients after monitoring for a year post MSC therapy. Neuro-restoration and clinical improvement in terms of modified Barthel index, functional independence measure and extended Glasgow Outcome Scale were evident among patients having MSC therapy compared to patients receiving placebos. CONCLUSION Intravenous administration of autologous bone marrowderived MSC is safe and has the potential of improving neurological functions in chronic stroke patients with severe disability.     

第16届国际生物物理大会的通知

第十六届国际生物物理大会(16th International Biophysics Congress,简称16th IBC)暨第52届美国生物物理年会(52nd Annual Meeting of the Biophysical Society)将于2008年2月2～6日在美国加利福尼亚Long Beach举行.     

第17届摇蚊学国际会议在南开大学召开

2009年7月5-10日第17届摇蚊学国际会议(The 17th International Symposium on Chironomidae)在南开大学召开.     

胶陀螺的光敏活性组分

用石油醚、氯仿、乙酸乙酯和丙酮对胶陀螺子实体进行梯度提取,得到的粗提物做光敏活性药理试验,结果表明:胶陀螺的氯仿和乙酸乙酯粗提取物有明显的光敏活性。将氯仿和乙酸乙酯的粗提物分别用不同比例的氯仿—甲醇进行反复柱层析,同时配合光敏活性药理试验,得到6个有光敏活性的组分,分别为c2、c3、c4、c5、c6和c11。将6个组分合并后继续分离,最终得到1个有橙黄色荧光点的成分,对其进行光敏活性药理试验,结果证明其为胶陀螺的光敏活性成分。     

BRIEF INTRODUCTI0N TO ISSN 0253-2700

Key title=YUNNAN ZHIWU YANJIU Latin name=Acta Botanica Yunnanica (Quartely.Started in 1979.Date of issue:the 5th of February,May,August and November.Number of pages:ca.120).     

APS1997全国生化药理与生物工程新药研制与开发学术研讨会通知

中国药理学会中国药理学报(ＡＰＳ)编辑委员会将于1997年11月5～8日在广东省珠海市召开“全国生化药理与生物工程新药研制与开发学术研讨会”.会议将由珠海恒通生物工程制药公司协办.会议将邀请中国药理学报著名专家编委作有关专题报告.会议主题为总结和交流:①生物化学、生物物理学、生化药理学研究进展及在新药研制与开发中的应用;②生物工程的研究进展,基因工程、细胞工程、蛋白质工程、酶工程、发酵工程等生物技术在新药研究与开发中的应用;③参观考察恒通生物工程制药公司并组织座谈.会议征文要求:来稿必须是未公开发表过的学术性论文.…     

非洲加纳籽生物学特性及其化学成分(综述)

现代植物化学研究发现,非洲加纳籽的主要化学成分为5-羟基色氨酸;现代药理研究表明,该植物具有抗抑郁、抑制肥胖和抗氧化等各种药理活性。本文系统介绍非洲加纳籽的生物学特性及化学成分与药理药效的国内外研究进展,为其引种驯化与深度开发提供理论依据。     

5th Annual Meeting of European Working Group on Legionella Infections

Moscow—1990 May 16—18 Session 1(16th of May) European epidemiological picture 1989/90 presentations from each country epidemiology and prevention Session 2(17th of May)     

The 8~(th) International Bioinformatics Workshop (IBW2010)

June 4-6, 2010, Wuhan, China Call for PapersThe 8th International Bioinformatics Workshop (IBW2010) will be held from June 4th to 6th, 2010 in Wuhan University, Wuhan, China. The workshop is organized by Wuhan University,     

The 8th International Bioinformatics Workshop (IBW2010)

<正>Wuhan,ChinalJune,2010 The 8th International Bioinformatics Workshop (IBW2010) will be held from June 4th to 6th,2010 in Wuhan University,Wuhan,China.The workshop is organized by Wuhan University,coorganized by Journal of Genetics and Genomics and     

The 10th National Congress of Genetic Society of China: Celebrating its 40th anniversary in Nanjing

正The 10~(th) National Congress of Genetic Society of China(GSC)was held on November 26th?29th,2018 in Nanjing,where GSC was established and the First National Congress of GSC was held in 1978.This congress was sponsored by GSC,co-sponsored by Genetics Society of Jiangsu Province,Nanjing Agricultural University,State Key Laboratory of Crop Genetics and Germplasm     

磷酸二酯酶5参与平滑肌功能调节的机制

磷酸二酯酶5(phosphodiesterase type 5,PDE5)又称对环鸟苷酸特异的磷酸二酯酶(cGMP-specific phosphodiesterase),广泛分布于机体的平滑肌细胞中,通过对细胞内特定区域的cGMP水平的调节,参与平滑肌(收缩、舒张)状态的快速调控.现对PDE5的基因表达和酶活性的调控方式,亚细胞分布,以及在平滑肌中的调节机制和药理应用进行综述.     

“生化药理与传统医学的桥梁”国际学术讨论会将在北京举行

中国医学科学院、中国协和医科大学与中国药理学会生化药理分科学会将联合举办一个小型国际学术讨论会:“Bridging Biochemical Pharmacology and Triditional Medicine”。会议主题有:(1)生化药理研究的方法学;(2)传统药有效成份的代谢;(3)根据生化药理学研究传统医药的作用机理。届时将有日本、南朝鲜、香港、苏联、英国、波兰、加拿大等国和地区以及中国大陆著名专家做学科发展前沿的学术报告,同时还将举办小型论文报告会。     

关于第五届国际药用菌大会延期的通知

<正>受全球甲型H1N1流感疫情继续蔓延的影响,原定于2009年6月18日-21日召开的第五届国际药用菌大会(The 5th International Medicinal Mushroom Conference),经大会组委会讨论,     

水牛胎儿成纤维细胞体外培养体系的初步建立

为探讨适合水牛胎儿成纤维细胞(BFF)的体外培养体系,采用常规组织块法和胰蛋白酶消化法原代培养BFF均获得了较多的成纤维细胞,但后者所得细胞的活力不如前者高,且死细胞也较多;传代或冻存成纤维细胞时用4℃预冷的胰蛋白酶室温下消化所得的细胞比37℃热消化的细胞更圆、更有光泽;跟踪32代的细胞冷冻复苏率均达70%～80%;染色体分析结果显示,二倍体细胞所占比例始终保持在80%～90%之间,各代细胞(5th、10th、15th)之间差异不显著(P>0.05).结果 表明,组织块法原代培养、4℃预冷胰蛋白酶室温消化传代细胞的培养体系比较适合水牛胎儿成纤维细胞的培养.