医护人员心理资本、应对方式与工作倦怠关系

目的 探讨医护人员心理资本、应对方式与工作倦怠的关系。方法 采用心理资本量表、简易应对方式量表和Maslach工作倦怠量表通用版对河北省某省级三甲医院101名医护人员进行调查。结果 （1）医生自我效能得分高于护士,成就感低落得分低于护士(P<0.05)。（2）心理资本与工作倦怠（乐观与成就感低落相关除外）呈显著负相关(P<0.01 or P<0.05),消极应对与成就感低落呈显著正相关(P<0.01)。（3）希望对情绪衰竭和玩世不恭有明显负向预测(P<0.01,P<0.001),自我效能(P<0.001)和消极应对(P<0.05)对成就感低落分别有负向和或正向预测作用。结论 提升心理资本水平,调整消极应对方式能有效预防和矫治医护人员工作倦怠;医院管理层应关注护士群体的心理状态。     

南宁市医生职业情绪劳动表现策略调查及相关因素分析

目的 探讨医生职业的情绪表现策略及相关影响因素,为提高卫生人力资源管理效率提供依据。方法 采用情绪劳动量表(ELS)、简易症状自评量表、简易应对方式问卷(SCSQ)、社会支持量表(SSRS)和工作倦怠调查问卷对276名医生进行问卷调查。结果 医生的情绪表现策略依次为深层表现和自然表现以及表面表现。随着工龄增加,自然表现应用减少,深层表现应用增多。医生的心理卫生症状、应对方式均分比常模高。医生的工作倦怠显示中重度。表面表现策略与躯体化、焦虑、抑郁、敌对、应对方式、情绪衰竭呈正相关（r=0.23～0.33）;自然表现策略与躯体、焦虑、积极应对呈负相关（r=-0.24～-0.27）,与社会支持呈正相关（r=0.25）;深层表现策略与社会支持呈正相关（r=0.27）。结论 医生职业的情绪表现策略与工作倦怠、心理卫生和社会支持有相关性,医院管理者可制定相应的措施减轻员工的情绪劳动压力,提高医疗服务质量。     

哈尔滨地区手术室护士职业倦怠现状与社会支持的相关分析

目的:研究哈尔滨地区手术室护士职业倦怠现状与社会支持现状,分析其相关性,通过提高社会支持,减轻职业倦怠感.方法:通过目的抽样选取哈尔滨地区8所二甲以上的医院468名手术室护士进行调查,回收有效问卷450份,调查工具包括一般情况调查表、职业倦怠量表与社会支持量表.结果:在职业倦怠量表中,情感耗竭得分为29.42± 9.58,去个性化得分为7.45± 4.32,个人成就感得分为28.12±9.29.手术室护士的情感耗竭与主观支持存在显著相关(P＜0.01).去个性化与主观支持和支持利用度存在显著相关(P＜0.05,P＜0.01).结论:预防手术室护士职业倦怠,应努力增加护士的社会支持,塑造良好的人格,更好地为社会大众服务.     

工作倦怠与交通警察生活质量的关系

目的:探讨交通警察工作倦怠与生活质量的关系。方法:采用MBI-GS和生活质量问卷调查了某市185名交通警察,运用相关分析和回归分析处理数据。结果:交通警察的情绪衰竭与其生活质量显著负相关(P<0.01);玩世不恭也与生活质量显著负相关(P<0.01);职业效能与生活质量显著正相关(P<0.05)。结论:降低工作倦怠,可以有效提高交通警察的生活质量。     

医生职业倦怠量表的编制及信效度检验

目的:编制医生职业倦怠量表.方法:通过查阅文献、访谈及专家讨论,建立量表结构,并确定初始量表项目48条.在西安的两所三级甲等医院施测,2次分别选取176和436名医生作为样本.采用项目分析、探索性因素分析、信度分析、验证性因素分析等统计方法对数据进行统计分析.结果:医生职业倦怠量表由六个因素构成:疲劳感、工作能力下降、投入性下降、成就感降低、工作控制感下降以及工作前景.共有30个项目,量表总分与各因素之间的相关系数0.541～0.856(P＜0.001).六个因素的α系数在0.886～0.896之间,总量表的α系数为0.894.验证性因素分析拟合度较高(RESEA=0.062,GFI=0.859,CFI=0.842,IFI=0.851).医生职业倦怠量表总分及各因子分与工作倦怠问卷的总分及各因子分之间具有显著的相关性(P＜0.05).结论:编制的医生职业倦怠量表信度和效度符合心理测量学要求,可以作为医生职业倦怠测量的工具.     

慢性心力衰竭患者自我管理的现状及影响因素分析(英文)

目的:了解慢性心力衰竭患者自我管理的现状及影响因素。方法:采用自行设计的心力衰竭自我管理量表、心力衰竭知识测评量表、患者信息调查表和社会支持评定量表、抑郁自评量表调查160例慢性心力衰竭患者的现状。结果:心衰患者自我管理状况呈中等水平,自我管理水平与教育程度、心衰相关知识水平以及社会支持程度呈中度正相关关系,与抑郁情绪和年龄呈中度负相关关系。结论:慢性心衰患者自我管理水平受其生理、心理及社会等多因素的影响。     

大学生学习倦怠、自尊与生活满意度的关系研究

目的:探讨大学生学习倦怠、自尊以及生活满意度的关系.方法:采用学习倦怠量表、自尊量表(SES)以及生活满意度量表对446名大学生进行测试.结果:(1)学习倦怠存在性别差异,大学男生在学习倦怠的成就感低方面显著高于大学女生;(2)大三学生在行为不当方面显著低于大四学生;在成就感低方面显著低于大一学生;(3)情绪低落及成就感低对自尊以及生活满意度有显著的预测作用.结论:缓解大学生学习倦怠、提高其自尊水平与生活满意度有利于提高其心理健康.     

工作倦怠与交通警察生活质量的关系

目的：探讨交通警察工作倦怠与生活质量的关系。方法：采用MBI-GS和生活质量问卷调查了某市185名交通警察,运用相关分析和回归分析处理数据。结果：交通警察的情绪衰竭与其生活质量显著负相关（P〈0.01）;玩世不恭也与生活质量显著负相关（P〈0.01）;职业效能与生活质量显著正相关（P〈0.05）。结论：降低工作倦怠,可以有效提高交通警察的生活质量。     

护士职业压力与职业倦怠的相关性研究

目的:了解护士职业压力、职业倦怠现状;探讨两者之间的关系。方法:方便抽样,抽取哈尔滨市5所三级医院的468名护士进行问卷调查。采用护士一般情况调查表、护士工作压力源量表、职业倦怠量表进行调查。结果:护士职业倦怠程度为中等,去人格化属于中度倦怠,情感衰竭、低成就感程度达到了高度倦怠;职业压力得分为87.56±20.43,以工作量及时间分配维度压力最高,病人护理维度压力最低。情感耗竭与除工作环境及资源之外的职业压力维度呈显著正相关;去人格化与职业压力各维度均呈显著正相关;低成就感与职业压力中护理专业及工作、病人护理呈显著负相关(P0.05)。护士职业压力各维度对其职业倦怠的3个维度均有较好的预测作用,尤其对护士情感耗竭的解释程度达25.5%。结论:护士职业倦怠现象不容忽视,护理管理者有针对性的对护士进行管理,鼓励护士加强自身修养、学会自我疏导,适当授权等是降低护士职业倦怠的正性激励措施。     

医务人员工作倦怠与特质情绪智力相关关系的研究

目的 通过考察医务人员工作倦怠与特质情绪智力的相关关系,为探索改善医务人员工作倦怠状况的方法提供依据。方法 采用随机抽样的方式对552名医务人员进行工作倦怠和特质情绪智力问卷的调查。结果 (1)工作倦怠与特质情绪智力负性相关关系显著;(2)总体上,特质情绪智力对工作倦怠具有一定的负向预测作用。结论 可以通过对医务人员特质情绪智力的培养改善其工作倦怠感,培训方案的设计要注意整体性和全面性。

     

Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures

Defects in mitochondrial energy metabolism have been implicated in the pathology of several neurodegenerative disorders. In addition, the reactive metabolites generated from the metabolism and oxidation of the neurotransmitter dopamine (DA) are thought to contribute to the damage to neurons of the basal ganglia. We have previously demonstrated that infusions of the metabolic inhibitor malonate into the striata of mice or rats produce degeneration of DA nerve terminals. In the present studies, we demonstrate that an intrastriatal infusion of malonate induces a substantial increase in DA efflux in awake, behaving mice as measured by in vivo microdialysis. Furthermore, pretreatment of mice with tetrabenazine (TBZ) or the TBZ analogue Ro 4-1284 (Ro-4), compounds that reversibly inhibit the vesicular storage of DA, attenuates the malonate-induced DA efflux as well as the damage to DA nerve terminals. Consistent with these findings, the damage to both DA and GABA neurons in mesencephalic cultures by malonate exposure was attenuated by pretreatment with TBZ or Ro-4. Treatment with these compounds did not affect the formation of free radicals or the inhibition of oxidative phosphorylation resulting from malonate exposure alone. Our data suggest that DA plays an important role in the neurotoxicity produced by malonate. These findings provide direct evidence that inhibition of succinate dehydrogenase causes an increase in extracellular DA levels and indicate that bioenergetic defects may contribute to the pathogenesis of chronic neurodegenerative diseases through a mechanism involving DA.     

Scurvy in capybaras bred in captivity in Argentine

In order to determine if the absence of vitamin C in the diet of capybaras (Hydrochoerus hydrochaeris) causes scurvy, a group of seven young individuals were fed food pellets without ascorbic acid, while another group of eight individuals received the same food with 1 g of ascorbic acid per animal per day. Animals in the first group developed signs of scurvy-like gingivitis, breaking of the incisors and death of one animal. Clinical signs appeared between 25 and 104 days from the beginning of the trial in all individuals. Growth rates of individuals deprived of vitamin C was considerably less than those observed in the control group. Deficiency of ascorbic acid had a severe effect on reproduction of another population of captive capybaras. We found that the decrease in ascorbic acid content in the diet affected pregnancy, especially during the first stages. The results obtained suggest that it is necessary to supply a suitable quantity of vitamin C in the diet of this species in captivity.     

Changes in lactate dehydrogenase activity in chicken tissues in hyperthyreosis in ontogenesis

The lactate dehydrogenase activity in reactions of lactate oxidation and synthesis was studied in subfractions of the chicken brain, heart and liver at the embryonal, early postembryonal and adult stages of development after thyroxine administration. It has been shown that during embryogenesis thyroxine predominantly enhanced the rate of lactate oxidation in the mitochondrial tissues. A marked increase in the lactate synthesis was found in cytoplasm of the adult chicken tissues. Specificity of enzyme activity alterations was detected in the chicken brain during ontogenesis after thyroxine administration.     

SSTR5 ablation in islet results in alterations in glucose homeostasis in mice

Somatostatin (SST) peptide is a potent inhibitor of insulin secretion and its effect is mediated via somatostatin receptor 5 (SSTR5) in the endocrine pancreas. To investigate the consequences of gene ablation of SSTR5 in the mouse pancreas, we have generated a mouse model in which the SSTR5 gene was specifically knocked down in the pancreatic beta cells (betaSSTR5Kd) using the Cre-lox system. Immunohistochemistry analysis showed that SSTR5 gene expression was absent in beta cells at three months of age. At the time of gene ablation, betaSSTR5Kd mice demonstrated glucose intolerance with lack of insulin response and significantly reduced serum insulin levels. Insulin tolerance test demonstrated a significant increase of insulin clearance in vivo at the same age. In vitro studies demonstrated an absence of response to SST-28 stimulation in the betaSSTR5Kd mouse islet, which was associated with a significantly reduced SST expression level in betaSSTR5Kd mice pancreata. In addition, betaSSTR5Kd mice had significantly reduced serum glucose levels and increased serum insulin levels at 12 months of age. Glucose tolerance test at an older age also indicated a persistently higher insulin level in betaSSTR5Kd mice. Further studies of betaSSTR5Kd mice had revealed elevated serum C-peptide levels at both 3 and 12 months of age, suggesting that these mice are capable of producing and releasing insulin to the periphery. These results support the hypothesis that SSTR5 plays a pivotal role in the regulation of insulin secretion in the mouse pancreas.