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Culture, Medicine, and Psychiatry - Using the large datasets available with new gene sequencing and biobank projects, behavioral geneticists are developing tools that attempt to predict individual...  相似文献   

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Developments in biotechnology are increasingly dependent on the extensive use of big data, generated by modern high‐throughput instrumentation technologies, and stored in thousands of databases, public and private. Future developments in this area depend, critically, on the ability of biotechnology researchers to master the skills required to effectively integrate their own contributions with the large amounts of information available in these databases. This article offers a perspective of the relations that exist between the fields of big data and biotechnology, including the related technologies of artificial intelligence and machine learning and describes how data integration, data exploitation, and process optimization correspond to three essential steps in any future biotechnology project. The article also lists a number of application areas where the ability to use big data will become a key factor, including drug discovery, drug recycling, drug safety, functional and structural genomics, proteomics, pharmacogenetics, and pharmacogenomics, among others.  相似文献   

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Intelligence, Coalitional Killing, and the Antecedents of War   总被引:2,自引:0,他引:2  
Advances in primatological research have recently led to a hypothesis that lethal coalitionary raiding in chimpanzees is the product of an evolutionarily adaptive "dominance drive" that disposes adult males to seek out low-cost opportunities for conspecific killing. This conclusion has been extended into a claim that human warfare and other forms of coalitional killing are outcomes of a hardwired, "demonic male" complex. Reversing this evidential approach, I argue from data on conspecific killing in humans that humans and chimpanzees have an aversion to killing conspecifics. Their lethal violence, I propose, is more parsimoniously explained as the result of a developed intelligence capable of envisioning the future and, when necessary, of disabling this aversion to achieve desired goals.  相似文献   

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Groups of individuals with headache, unilateral headache, and migraine, and a fourth group who had not had a headache in the previous year, were identified by questionnaire from a random sample of adults in the general population. Intelligence and social class were assessed in about 400 individuals. There was no evidence that individuals with migraine were more intelligent or of higher social class. There was, however, a suggestion that the more intelligent individuals with migraine, and those in social classes I and II, were more likely to consult a doctor for their headaches. This trend might explain the origin of the hypotheses associating migraine with intelligence and with social class.Random samples of individuals with migraine with headache and without headache in the previous year were the probands for a family study. There were 524 first-degree relatives over 21 years of age who lived in South Wales. Headache histories, obtained “blindly” from over 99% of these relatives with a standard questionnaire, were classified as migraine, possible migraine, headache, or without headache in the previous year. The prevalence of migraine in the families of the migrainous probands was nearly twice as high as the prevalence in the other families, but this difference was not statistically significant. It is suggested that family history should not be included in the definition of migraine and that heredity is much less important in migraine than is usually supposed.  相似文献   

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Conceptual styles are rule-sets for the selection and organization of sense data. Two mutually incompatible conceptual styles are identified—relational and analytic. Relational and analytic methods of conceptual organization appear to have been developed and reinforced in shared-function and formally organized primary groups, respectively, as socialization settings. Each style affects its carrier's ability to deal effectively with the alternate kind of group process requirements. A distinction is drawn between culture conflict and related notions of deprivation and culture difference. When the conceptual styles used between individuals and groups are mutually incompatible, culture conflict may be said to exist, whether or not the other phenomena are also present. It is found that highly relational pupils in the analytic school environment represent this type of culture conflict regardless of their native ability or the variety and relevance of their experience backgrounds. This difficulty is not obviated by developing context-free situations. Item solution requirements for common nonverbal tests of intelligence, for instance, focus directly on expertise in using the analytic rule-set as a measure of intelligence. Their culture bias has, thus, not been reduced but has been moved to a higher level of abstraction. Conceptual rule-sets also affect the assimulation of experience content. They determine to a great extent the number and nature of contextual attributes that will appear relevant to individuals. In addition, because a wide variety of social and psychological behaviors are meaningful only when they follow from these rule-sets, conceptual styles contribute to the formation of logically derived normative systems.  相似文献   

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The origin of preferences and values is an unresolved theoretical problem in behavioural sciences. The Savanna-IQ Interaction Hypothesis, derived from the Savanna Principle and a theory of the evolution of general intelligence, suggests that more intelligent individuals are more likely to acquire and espouse evolutionarily novel preferences and values than less intelligent individuals, but general intelligence has no effect on the acquisition and espousal of evolutionarily familiar preferences and values. Ethnographies of traditional societies suggest that exclusively homosexual behaviour was probably rare in the ancestral environment, so the Hypothesis would predict that more intelligent individuals are more likely to identify themselves as homosexual and engage in homosexual behaviour. Analyses of three large, nationally representative samples (two of which are prospectively longitudinal) from two different nations confirm the prediction.  相似文献   

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Intelligence     
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Intelligence is considered as one level in a multiple level model of evolution, each level being defined by its own units of selection and by the capacity to furnish adaptations to environmental events that occur within particular frequency bands. The specific implications for intelligence are that it is never an across-species generalist capacity but always focussed around species-typical adaptive behaviours; and that it interacts with evolution at other levels, notably at the sociocultural level in the case of Humans.  相似文献   

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