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Optimisation of the post-validation process: the report and recommendations of ECVAM Workshop 67 总被引:1,自引:0,他引:1
Bottini AA Alepee N Phillips B Gribaldo L De Silva O Hartung T Hendriksen C Kuil J Pazos P Rhein C Schiffelers MJ Stokes W Theobald A Vidal JM Van de Sandt H Breier S Sintes JR Blaauboer B 《Alternatives to laboratory animals : ATLA》2008,36(3):353-366
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The validation of a test method is the process by which the relevance and reliability of the method are assessed for a particular purpose. It is an essential stage in the evolution of the method from its development to its acceptance and application for regulatory purposes. The principles according to which alternative tests should be validated have been agreed at an international level, although the actual process by which the validation process is conducted varies between different validation authorities. This paper summarises the principles of alternative test development and validation, and describes how the principles have been applied to the validation of in vitro tests by ECVAM. 相似文献
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Gennari A van den Berghe C Casati S Castell J Clemedson C Coecke S Colombo A Curren R Dal Negro G Goldberg A Gosmore C Hartung T Langezaal I Lessigiarska I Maas W Mangelsdorf I Parchment R Prieto P Sintes JR Ryan M Schmuck G Stitzel K Stokes W Vericat JA Gribaldo L;ECVAM Workshop 《Alternatives to laboratory animals : ATLA》2004,32(4):437-459
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Physiologically-based Kinetic Modelling (PBK Modelling): meeting the 3Rs agenda. The report and recommendations of ECVAM Workshop 63 总被引:2,自引:0,他引:2
Bouvier d'Yvoire M Prieto P Blaauboer BJ Bois FY Boobis A Brochot C Coecke S Freidig A Gundert-Remy U Hartung T Jacobs MN Lavé T Leahy DE Lennernäs H Loizou GD Meek B Pease C Rowland M Spendiff M Yang J Zeilmaker M 《Alternatives to laboratory animals : ATLA》2007,35(6):661-671
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Coecke S Ahr H Blaauboer BJ Bremer S Casati S Castell J Combes R Corvi R Crespi CL Cunningham ML Elaut G Eletti B Freidig A Gennari A Ghersi-Egea JF Guillouzo A Hartung T Hoet P Ingelman-Sundberg M Munn S Janssens W Ladstetter B Leahy D Long A Meneguz A Monshouwer M Morath S Nagelkerke F Pelkonen O Ponti J Prieto P Richert L Sabbioni E Schaack B Steiling W Testai E Vericat JA Worth A 《Alternatives to laboratory animals : ATLA》2006,34(1):49-84
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