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Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex 下载免费PDF全文
Narita T Yamaguchi Y Yano K Sugimoto S Chanarat S Wada T Kim DK Hasegawa J Omori M Inukai N Endoh M Yamada T Handa H 《Molecular and cellular biology》2003,23(6):1863-1873
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Espinosa JM 《Molecular cell》2010,40(4):507-508
Pausing of RNA polymerase II (RNAPII) at the 5' end of genes is a widespread phenomenon in metazoans, but the role of this event in gene regulation is poorly understood. Gilchrist et al. (2010) now demonstrate that RNAPII pausing counteracts DNA-influenced nucleosome organization to allow precise gene activation. 相似文献
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