Variation in Tolerance to Parasites Affects Vectorial Capacity of Natural Asian Tiger Mosquito Populations

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Malassezia Is Associated with Crohn’s Disease and Exacerbates Colitis in Mouse Models

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Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease

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Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis

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An Excitatory Neural Assembly Encodes Short-Term Memory in the Prefrontal Cortex

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Optimized Mitochondrial Targeting of Proteins Encoded by Modified mRNAs Rescues Cells Harboring Mutations in mtATP6

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Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease

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Human ESC-Derived Chimeric Mouse Models of Huntington’s Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation

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Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

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Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice

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PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer

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Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology

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Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients

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Mutant TDP-43 Causes Early-Stage Dose-Dependent Motor Neuron Degeneration in a TARDBP Knockin Mouse Model of ALS

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Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

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Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody

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Age- and α-Synuclein-Dependent Degeneration of Dopamine and Noradrenaline Neurons in the Annual Killifish Nothobranchius furzeri

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Activation of the Rostral Intralaminar Thalamus Drives Reinforcement through Striatal Dopamine Release

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α6-Containing Nicotinic Acetylcholine Receptor Reconstitution Involves Mechanistically Distinct Accessory Components

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Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways

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