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The Progress in Vaccination against Cancer (PIVAC) series of conferences celebrated 10 years of existence by returning to
Cambridge, where the first meeting was held in the year 2001. This year, the conference at St Catharine’s college was full
of hope for the future of immunotherapy against cancer with the introduction of prophylactic vaccines, combination therapies
and the use of genetic vaccination (DNA vaccines) using old or new antigens vaccine formulations combined with the stimulation
of innate immunity, the use of Toll-like receptor (TLR) agonists and inhibition of checkpoint blockade to overcome the immunosuppression
created by the tumour microenvironment, offer exciting possibilities and new strategies. Indeed, enthusiasm is running high
amongst immunologists who are working to eradicate cancers following the recent completion of several large scale, randomized
phase III trials that have reported positive clinical results. The time when one will be able to immunize patients with minimal
or no measurable disease is therefore getting closer as we understand more about the host—tumour relationship that influences
regulatory immune pathways. 相似文献
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This report summarizes the lectures and posters presented at the International Society for Invertebrate Neurobiology’s 13th symposium held 26–30 August 2015, at the Balaton Limnological Institute, MTA Centre for Ecological Research, Tihany, Hungary. The symposium provided an opportunity for scientists working on a range of topics in invertebrate neurobiology to meet and present their research and discuss ways to advance the discipline. 相似文献
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