How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor

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Structural insights into assembly and function of GluN1-2C,GluN1-2A-2C,and GluN1-2D NMDARs

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Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells

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IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells

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Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis

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Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

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Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones

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Divergent Roles for Macrophage C-type Lectin Receptors,Dectin-1 and Mannose Receptors,in the Intestinal Inflammatory Response

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Alternating sources of perisomatic inhibition during behavior

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ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1

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Hydathode immunity protects the Arabidopsis leaf vasculature against colonization by bacterial pathogens

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Pulmonary neuroendocrine cells sense succinate to stimulate myoepithelial cell contraction

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Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells

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Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR/Erk2 Signaling Pathway during Embryogenesis

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Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK

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Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity

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Area Postrema Cell Types that Mediate Nausea-Associated Behaviors

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A single residue confers selective loss of sugar sensing in wrynecks

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From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease

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The Arabidopsis TIR-NBS-LRR protein CSA1 guards BAK1-BIR3 homeostasis and mediates convergence of pattern- and effector-induced immune responses

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