Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells

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Lyso-PAF,a biologically inactive phospholipid,contributes to RAF1 activation

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Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via activating inosine/A2aR pathway

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A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin

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Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture,phosphorylation, and ubiquitylation

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DIENELACTONE HYDROLASE LIKE PROTEIN1 negatively regulates the KAI2-ligand pathway in Marchantia polymorpha

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Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state

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Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1

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Structural and Functional Analyses of the FAM46C/Plk4 Complex

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An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress

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Follicular regulatory T cells produce neuritin to regulate B cells

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Nov/CCN3 Enhances Cord Blood Engraftment by Rapidly Recruiting Latent Human Stem Cell Activity

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Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome

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Binding of Ca2+-independent C2 domains to lipid membranes: A multi-scale molecular dynamics study

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NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation

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The Hox Transcription Factor Ubx Ensures Somatic Myogenesis by Suppressing the Mesodermal Master Regulator Twist

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Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells

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Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression

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TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease

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Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

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