The Phosphatase PP1 Promotes Mitotic Slippage through Mad3 Dephosphorylation

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Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome

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A FOXO-dependent replication checkpoint restricts proliferation of damaged cells

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The neuropeptide receptor npr-38 regulates avoidance and stress-induced sleep in Caenorhabditis elegans

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Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes

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Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma

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Homeostatic Control of Meiotic Prophase Checkpoint Function by Pch2 and Hop1

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Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis

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m6A RNA methylation regulates promoter- proximal pausing of RNA polymerase II

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Bacterial developmental checkpoint that directly monitors cell surface morphogenesis

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COMET Functions as a PCH2 Cofactor in Regulating the HORMA Domain Protein ASY1

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CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

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FOXD3 Regulates VISTA Expression in Melanoma

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DENND2B activates Rab35 at the intercellular bridge,regulating cytokinetic abscission and tetraploidy

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Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer

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Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28

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Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation

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NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion

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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

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Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation

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