Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A

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RIPK1 Promotes Energy Sensing by the mTORC1 Pathway

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IQGAP1 Negatively Regulates HIV-1 Gag Trafficking and Virion Production

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TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

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Self-incompatibility requires GPI anchor remodeling by the poppy PGAP1 ortholog HLD1

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PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway

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Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1

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A non-canonical target-binding site in Munc18-1 domain 3b for assembling the Mint1-Munc18-1-syntaxin-1 complex

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HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway

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RIF1 suppresses the formation of single-stranded ultrafine anaphase bridges via protein phosphatase 1

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Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors

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H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ

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HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways

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Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism

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CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition

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HIF-1α drives resistance to ferroptosis in solid tumors by promoting lactate production and activating SLC1A1

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CARM1 regulates replication fork speed and stress response by stimulating PARP1

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

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Molecular insight into the PCNA-binding mode of FBH1

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Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex

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