Estimation of the electron density and radiative energy losses in a calcium plasma source based on an electron cyclotron resonance discharge

The parameters of a calcium plasma source based on an electron cyclotron resonance (ECR) discharge were calculated. The analysis was performed as applied to an ion cyclotron resonance system designed for separation of calcium isotopes. The plasma electrons in the source were heated by gyrotron microwave radiation in the zone of the inhomogeneous magnetic field. It was assumed that, in such a combined trap, the energy of the extraordinary microwave propagating from the high-field side was initially transferred to a small group of resonance electrons. As a result, two electron components with different transverse temperatures—the hot resonance component and the cold nonresonance component—were created in the plasma. The longitudinal temperatures of both components were assumed to be equal. The entire discharge space was divided into a narrow ECR zone, where resonance electrons acquired transverse energy, and the region of the discharge itself, where the gas was ionized. The transverse energy of resonance electrons was calculated by solving the equations for electron motion in an inhomogeneous magnetic field. Using the law of energy conservation and the balance condition for the number of hot electrons entering the discharge zone and cooled due to ionization and elastic collisions, the density of hot electrons was estimated and the dependence of the longitudinal temperature T _e∥ of the main (cold) electron component on the energy fraction β lost for radiation was obtained.     

Generation of the electric field pulsating at 2.45 GHz in the CERA-RX(C) electron cyclotron resonance source and its influence on X-ray generation efficiency

A mechanism for the onset of pulsations of the electric field at a pumping frequency of 2.45 GHz is determined, and its influence on the efficiency of characteristic X-ray generation in the CERA-RX(C) source is shown.     

Linear theory of electron cyclotron instability of electromagnetic waves in a magnetoactive plasma waveguide

The linear stage of electron cyclotron instability of quasi-TE modes in a waveguide filled with a magnetoactive plasma is studied using a kinetic approach. The dispersion relation of the instability is derived analytically. It is shown that the presence of the plasma can reduce both the linear instability growth rate and the instability region; in this case, the maximum of the growth rate is displaced toward lower frequencies. The results obtained are compared with the available experimental observations. They can be useful for optimizing the operating regimes of high-power continuous-wave gyrotrons.     

Two-slope soft X-ray spectra observed in experiments on electron cyclotron resonance plasma heating in the L-2M stellarator

In experiments on the generation and electron cyclotron resonance heating (ECRH) of plasma in the L-2M stellarator, non-Maxwellian two-slope soft X-ray (SXR) spectra were observed. The temperatures of the thermal and epithermal components of the spectra were measured as functions of the heating power and plasma density. A hypothesis based on the experimental results is suggested to explain the formation mechanism of two-slope SXR spectra in the ECRH experiments at the L-2M stellarator. The measured SXR spectra are compared with the results of numerical simulations.     

Lasing without inversion and electromagnetically induced transparency under electron cyclotron resonance conditions

Parametric effects of lasing without inversion and electromagnetically induced transparency in classical systems are considered. The characteristic features of the effect of lasing without inversion in ensembles of classical electrons are analyzed using an “inversionless” cyclotron maser as an example. A theory of the effect of electromagnetically induced transparency is developed for electron cyclotron waves in a high-temperature plasma. Possible applications of these two effects in plasma physics and microwave electronics are discussed.     

Pulse-periodic generation of supershort avalanche electron beams and X-ray emission

Pulse-periodic generation of supershort avalanche electron beams (SAEBs) and X-ray emission in nitrogen, as well as the transition from a single-pulse mode to a pulse-periodic mode with a high repetition frequency, was studied experimentally. It is shown that, in the pulse-periodic mode, the full width at halfmaximum of the SAEB is larger and the decrease rate of the gap voltage is lower than those in the single-pulse mode. It is found that, when the front duration of the voltage pulse at a nitrogen pressure of 90 Torr decreases from 2.5 to 0.3 ns, the X-ray exposure dose in the pulse-periodic mode increases by more than one order of magnitude and the number of SAEB electrons also increases. It is shown that, in the pulse-periodic mode of a diffuse discharge, gas heating in the discharge gap results in a severalfold increase in the SAEB amplitude (the number of electrons in the beam). At a generator voltage of 25 kV, nitrogen pressure of 90 Torr, and pulse repetition frequency of 3.5 kHz, a runaway electron beam was detected behind the anode foil.     

Ray trajectories near the electron cyclotron resonance surface in an axisymmetric magnetic trap

Characteristic features of the propagation of electromagnetic electron cyclotron waves in the vicinity of the electron cyclotron resonance surface are investigated both analytically and numerically with allowance for variation in the magnetic field strength and a corresponding variation in the magnetic field direction. It is demonstrated that variation in the magnetic field direction can qualitatively change the wave propagation pattern and can markedly affect the efficiency of electron cyclotron resonance plasma heating in an axisymmetric magnetic trap.     

Search for cyclotron resonance in cells in vitro

There are a number of reports of the plasma membrane transport of Ca2+ in biological systems being enhanced by low frequency electromagnetic fields (EMF), including reports that the enhancement involves a resonance-type response at the cyclotron frequency for Ca2+ ions for geomagnetic values of the magnetic field. Using the fluorescent probe fura2, we find no evidence for changes in cytosolic calcium concentration in BALB/c3T3, L929, V-79, and ROS, a rat osteosarcoma cell line, at the application of both resonant and nonresonant EMF.     

Modeling of Coulomb collisions in a kinetic description of the electron cyclotron resonance plasma heating

The electron distribution function is modeled numerically with allowance for Coulomb collisions and quasilinear effects under cyclotron resonance conditions by solving a two-dimensional kinetic equation containing the quasilinear diffusion operator and the Coulomb collision operator in the Landau form. Two simplified model collision integrals that make it possible to describe electron heating by microwave radiation are considered. The first model collision operator is obtained by introducing the parametric time dependence of the temperature of the background Maxwellian electrons into the linear collision integral. It is shown that the heating of the bulk electrons can be described in a noncontradictory way if the temperature dynamics of the background electrons is calculated from the equation of energy balance, which is governed by the amount of the microwave power absorbed by the resonant electrons with the distribution function modified due to quasilinear effects. This conclusion is confirmed in a more rigorous fashion by comparing the solutions obtained using the first model Coulomb collision integral with those obtained using the second model integral, namely, the nonlinear operator derived by averaging the distribution function of the scattering electrons over pitch angles. The time-dependent linear collision integral is used to obtain analytic solutions describing quasi-steady electron heating with allowance for the quasilinear degradation of microwave power absorption.     

Generation of hard X-ray emission by the electron beam in plasma focus facilities

The results of measurements of the temporal characteristics of hard X-ray emission generated at plasma focus (PF) facilities are presented. Mechanisms of electron beam generation in the PF pinch are analyzed. On the basis of the known mechanisms and experimental data on the measured temporal characteristics of hard X-ray pulses, a mechanism of fast electron generation that takes into account both the effect of the anomalous pinch resistance and the current redistribution in the near-pinch region is proposed. The processes occurring in the pinch plasma are simulated on the basis of the proposed mechanism by using the MicroCap code. It is shown that only a small fraction of the discharge current (1–10%) can be transformed into the electron beam current.     

Endogenous cyclotron ion resonance therapy for keratoconus: preliminary results

Four keratoconus patients, ranging in age from 24 to 62, and at various stages of the disease, were treated with the combined therapy of low frequency whole body ion cyclotron resonance and magnetic "applicators" applied locally to the temporal area. Following careful examination of the corneal profile using video image acquisition, treatments were given twice a week, for a total of 15 treatments. Following this regimen there were evident morphological changes in several layers of the corneas for all the patients, as well as increased transparency. Despite the limited number of patients in this preliminary study, the positive results suggest a larger follow up study of the effects of ICR treatment for keratoconus.     

Effect of microwave reflection from the region of electron cyclotron resonance heating in the L-2M stellarator

In experiments on electron cyclotron resonance (ECR) heating of plasma at the second harmonic of the electron gyrofrequency in the L-2M stellarator, the effect of partial reflection of high-power gyrotron radiation from the ECR heating region located in the center of the plasma column was revealed. The reflection coefficient is found to be on the order of 10^?3. The coefficient of reflection of an extraordinary wave from the second-harmonic ECR region is calculated in the one-dimensional full-wave model. The calculated and measured values of the reflection coefficient are found to coincide in order of magnitude.     

A miniaturized germanium-doped silicon dioxide-based surface plasmon resonance waveguide sensor for immunoassay detection

A surface plasmon resonance (SPR) waveguide immunosensor fabricated by germanium-doped silicon dioxide was investigated in this study. The designed waveguide sensor consisted of a 10 microm SiO(2) substrate layer (n=1.469), a 10 microm Ge-SiO(2) channel guide (n=1.492) and a 50 nm gold film layer for immobilization of biomolecules and SPR signal detection. The resultant spectral signal was measured by a portable spectrophotometer, where the sensor was aligned by a custom-designed micro-positioner. The results of the glycerol calibration standards showed that the resonance wavelength shifted from 628 to 758 nm due to changes of refractive index from 1.36 to 1.418. Flow-through immunoassay on waveguide sensors also showed the interactions of protein A, monoclonal antibody (mAb ALV-J) and avian leucosis virus (ALVs) resulted in wavelength shifting of 4.17, 3.03 and 2.18 nm, respectively. The SPR dynamic interaction could also be demonstrated successfully in 4 min as the sensor was integrated with a lateral flow nitrocellulose strip. These results suggest that SPR detection could be carried out on designed waveguide sensor, and the integration of nitrocellulose strip for sample filtering and fluid carrier would facilitate applications in point-of-care portable system.     

Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation

Mitochondrial aconitase (m-aconitase) contains a [4Fe-4S](2+) cluster in its active site that catalyzes the stereospecific dehydration-rehydration of citrate to isocitrate in the Krebs cycle. It has been proposed that the [4Fe-4S](2+) aconitase is oxidized by superoxide, generating the inactive [3Fe-4S](1+) aconitase. In this reaction, the likely products are iron(II) and hydrogen peroxide. Consequently, the inactivation of m-aconitase by superoxide may increase the formation of hydroxyl radical ((*)OH) through the Fenton reaction in mitochondria. In this work, evidence for the generation of (*)OH from the reaction of m-aconitase with superoxide is provided using ESR spin trapping experiments with 5-diethoxyphosphoryl-5-methyl-1-pyrroline N-oxide and alpha-phenyl-N-tert-butylnitrone. Formation of free ( small middle dot)OH was verified with the (*)OH scavenger Me(2)SO, which forms methyl radical upon reacting with (*)OH. The addition of Me(2)SO to incubation mixtures containing m-aconitase and xanthine/xanthine oxidase yielded methyl radical, which was detected by ESR spin trapping. Methyl radical formation was further confirmed using [(13)C]Me(2)SO. Parallel low temperature ESR experiments demonstrated that the generation of the [3Fe-4S](1+) cluster increased with increasing additions of superoxide to m-aconitase. This reaction was reversible, as >90% of the initial aconitase activity was recovered upon treatment with glutathione and iron(II). This mechanism presents a scenario in which (*)OH may be continuously generated in the mitochondria.     

Backscattering of gyrotron radiation and short-wavelength turbulence during electron cyclotron resonance plasma heating in the L-2M stellarator

Backscattering of gyrotron radiation (θ = π) by short-wavelength density fluctuations (k _⊥ = 30 cm^?1) in the plasma of the L-2M stellarator was studied under conditions of electron cyclotron resonance (ECR) plasma heating at the second harmonic of the electron gyrofrequency (75 GHz). The scattering of the O-wave emerging due to the splitting of the linearly polarized gyrotron radiation into the X- and O-waves was analyzed. The signal obtained after homodyne detection of scattered radiation is a result of interference of the reference signal, the quasi-steady component, and the fast oscillating component. The coefficients of reflection of the quasi-steady component, R ₌ ² (Y), and fast oscillating component, R _～ ² (Y), of scattered radiation are estimated. The growth of the R _～ ² (Y) coefficient from 3.7 × 10^?4 to 5.2 × 10^?4 with increasing ECR heating power from 190 to 430 kW is found to correlate with the decrease in the energy lifetime from 1.9 to 1.46 ms. The relative density of short-wavelength fluctuations is estimated to be 〈n _～ ² 〉/〈n _e ² 〉 = 3 × 10^?7. It is shown that the frequencies of short-wavelength fluctuations are in the range 10–150 kHz. The recorded short-wavelength fluctuations can be interpreted as structural turbulence, the energy of which comprises ～10% of the total fluctuations energy. Simulations of transport processes show that neoclassical heat fluxes are much smaller than anomalous ones. It is suggested that short-wavelength turbulence plays a decisive role in the anomalous heat transport.     

Peculiarities of charged particle dynamics under cyclotron resonance conditions

Peculiarities of the dynamics of charged particles interacting with electromagnetic radiation under nearly autoresonance conditions are analyzed. In particular, analysis of nonlinear cyclotron resonances shows that their widths increase when the autoresonance conditions are approached. In this case, however, the distance between nonlinear resonances increases even faster, due to which nonlinear resonances do not overlap and, accordingly, regimes with dynamic chaos do not occur. According to calculations, the dynamics of charged particles under the autoresonance conditions is very sensitive to fluctuations, the effect of which can be anomalously large and lead to superdiffusion. It is shown that, under the autoresonance conditions, particle dynamics on small time intervals can differ significantly from that on large time intervals. This effect is most pronounced in the presence of fluctuations in the system.     

On the cyclotron resonance model of ion transport.

The cyclotron-resonance model, which has been suggested as an explanation of a purported enhancement of transport of ions through the membranes of cells exposed to weak, low-frequency-modulated RF fields, is shown to be inconsistent with basic physical principles. Under the conditions of the model, in which the ions are presumed to circulate under the constraint of the earth's magnetic field, the radii of gyration of the ions would approximate 50 m and, thus, are much larger than the cells. Moreover, from general considerations, the collision-damping time of such ions is expected to be less than 10(-10) s, much smaller than the times of the order of 10(-2) s, shown to be necessary if the conditions for low-frequency resonance are to be satisfied.     

A high-power laser-driven source of sub-nanosecond soft X-ray pulses for single-shot radiobiology experiments

A large-scale, double-stream gas puff target has been illuminated by sub-kJ, near-infrared (NIR) focused laser pulses at the PALS facility (Prague Asterix Laser System) to produce high-energy pulses of soft X rays from hot, dense plasma. The double-puff arrangement ensures high gas density and conversion efficiency from NIR to X rays approaching that typical for solid targets. In addition, its major advantage over solid targets is that it is free of debris and has substantially suppressed charged-particle emission. The X-ray emission characteristics of the source were determined for a range of gases that included krypton, xenon, N(2), CO and N(2)-CO. A demonstrated application of the xenon-based source is a single-shot damage induction to plasmid DNA. The yields of single-strand breaks (SSBs) and double-strand breaks (DSBs) were determined as a function of energy fluence adjusted by varying distance of sample from the source and thickness of aluminum filters.