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Identification of Conserved Regulatory Elements in Mammalian Promoter Regions: A Case Study Using the PCK1 Promoter 总被引:2,自引:0,他引:2
George E. Liu Matthew T. Weirauch Curtis P. Van Tassell Robert W. Li Tad S. Sonstegard Lakshmi K. Matukumalli Erin E. Connor Richard W. Hanson Jianqi Yang 《基因组蛋白质组与生物信息学报(英文版)》2008,6(3):129-143
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Evolutionary conservation of histone modifications in mammals 总被引:1,自引:0,他引:1
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转录因子结合位点生物信息学研究进展 总被引:7,自引:0,他引:7
By using genome in situ hybridization (GISH) on root somatic chromosomes of allotetraploid derived from the cross Gossypium arboreum × G. bickii with genomic DNA (gDNA) of G. bickii as a probe, two sets of chromosomes, consisting of 26 chromosomes each, were easily distinguished from each other by their distinctive hybridization signals. GISH analysis directly proved that the hybrid G.arboreum×G. bickii is an allotetraploid amphiploid. The karyotype formula of the species was 2n = 4x = 52 = 46m (4sat) + 6sm (4sat). We identified four pairs of satellites with two pairs in each sub-genome. FISH analysis using 45S rDNA as a probe showed that the cross G. arboreum×G. bickii contained 14 NORs. At least five pairs of chromosomes in the G sub-genome showed double hybridization (red and blue) in their long arms, which indicates that chromatin introgression from the A sub-genome had occurred. 相似文献