微生物学实验多样化教学之初探

实验教学是微生物教学的重要组成部分,是培养学生动手能力、分析和解决问题等能力的重要教学环节.通过适当修改实验方案、整体设计实验、解决实际问题和开设综合性实验等途径实现多样化的教学模式,实践表明可以显著提高学生的学习兴趣,充分调动学生的积极性、主动性和创造性.     

微生物双语教学中的实施策略与实践—交互教学提升课堂活力

探讨了微生物双语教学中采用交互式教学以发挥学生主体地位以及教师鼓励作用的教学策略.为了“有助于达到人才培养目标”又保证培养质量,精选了英文原版教材和国内选编教材;基于双语教学资源平台,了解学情,灵活把握双语教学的中英文比例;通过微生物理论与实践相结合和英文演讲辩论等提升课堂活力;适度改革双语教学考核等方式提高微生物双语教学效果.     

临床微生物教学规范化、标准化研究

微生物形态特点各异,种类繁多复杂,而临床微生物教学不但担任着教学的责任,还身兼临床工作。为了培养具有扎实基础、较强实践能力的医学人才,在建立规范化和表转化的临床微生物教学,能够提高教学质量,能够提升学生综合分析问题和实践动手的能力,还能够使学生明确学习目的,从而促进临床微生物教学改革。     

密切联系实际，加强学生应用微生物技术能力的培养——高等农业院校植物生产类和资源环境类专业微生物学课程教学浅谈

《农业微生物学》既是高等农业院校植物生产类和资源环境类专业的专业基础课程,也是和应用微生物技术密切相关的课程。多年的教学实践表明,只有在教学中密切联系实际,强化学生应用微生物技术能力的培养,才能让学生既熟练掌握普通微生物学基础知识和基本技能,又能拓宽知识面,激发学生的学习兴趣。同时,根据人才培养方案、就业形势以及社会需求开设《实用微生物技术》和《食用菌生产》等选修课程,既满足学生对微生物实用技术学习的需要,也为生产企业培养了技术人员。     

微生物双语教学中的实施策略与实践

探讨了微生物双语教学中采用交互式教学以发挥学生主体地位以及教师鼓励作用的教学策略.为了“有助于达到人才培养目标”又保证培养质量,精选了英文原版教材和国内选编教材;基于双语教学资源平台,了解学情,灵活把握双语教学的中英文比例;通过微生物理论与实践相结合和英文演讲辩论等提升课堂活力;适度改革双语教学考核等方式提高微生物双语...     

改革微生物学实验教学 培养学生创新能力

对微生物学实验课程体系的教学内容、教学条件和手段、考核方法进行了改革和探索,创建适合于培养我校不同专业学生的微生物实验教学体系,从而提高学生动手能力,培养学生创新能力。     

"灵芝的实验室培养"实验设计

对人教版"微生物的实验室培养"的专题实验进行拓展,设计灵芝培养基的配制、菌种的接种、成菌培养等实验教学方案,让学生掌握基本微生物实验操作技术.通过灵芝培养实践,让学生体验科学技术与社会生活的联系.     

“微生物的利用”的教学构思

选修1“生物技术实践”模块均为实验内容．“微生物的利用”是其中的一个教学单元,本单元包含3个微生物实验。按照新课标对本模块的要求,实验涉及的基础知识主要通过学生自学来完成,教师的任务主要是指导学生进行实验设计、完成实验、收集整理数据、写出报告和讨论交流。实验课是发展学生科学探究能力的良好载体。在“微生物的利用”教学单元中,就如何培养学生实验技能,充分发展学生的科学探究能力谈谈自己的教学构思。     

慕课背景下“微生物工程”实验课开放式教学模式探索

慕课等线上学习平台是教育信息化的结果,结合慕课对传统教学进行突破是近年来教学改革的热点之一。"微生物工程"课程是高等院校生物技术、生物工程专业的必修课,该课程具有很强的应用性和实践性。为了加深学生对理论知识的理解、培养学生的科研思维,我们在微生物工程实验课的教学中引入了一种基于慕课教学资源的开放式教学模式。结果表明,这种慕课背景下的开放式教学在提升学生学习兴趣、锻炼学生创造性思维、增强学生科研素养、培养学生团队协作能力等方面都具有很好的效果。     

传统教学法与PBL结合在医学微生物学教学中的应用

PBL教学方法是一种全新的自主性的教学模式.把PBL教学方法引入病原微生物教学中,与传统教学方法相结合,提高了学生的学习自主性和学习的效果,并且进一步培养了学生的学习能力.这一尝试取得了良好的效果.     

A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility

正Dear Editor,In December 2019, a novel human coronavirus caused an epidemic of severe pneumonia(Coronavirus Disease 2019,COVID-19) in Wuhan, Hubei, China(Wu et al. 2020; Zhu et al. 2020). So far, this virus has spread to all areas of China and even to other countries. The epidemic has caused 67,102 confirmed infections with 1526 fatal cases     

Curcuminoids as inhibitors of thioredoxin reductase: A receptor based pharmacophore study with distance mapping of the active site

Curcumin is the yellow pigment of turmeric that interacts irreversibly forming an adduct with thioredoxin reductase (TrxR), an enzyme responsible for redox control of cell and defence against oxidative stress. Docking at both the active sites of TrxR was performed to compare the potency of three naturally occurring curcuminoids, namely curcumin, demethoxy curcumin and bis-demethoxy curcumin. Results show that active sites of TrxR occur at the junction of E and F chains. Volume and area of both cavities is predicted. It has been concluded by distance mapping of the most active conformations that Se atom of catalytic residue SeCYS498, is at a distance of 3.56 from C13 of demethoxy curcumin at the E chain active site, whereas C13 carbon atom forms adduct with Se atom of SeCys 498. We report that at least one methoxy group in curcuminoids is necessary for interation with catalytic residues of thioredoxin. Pharmacophore of both active sites of the TrxR receptor for curcumin and demethoxy curcumin molecules has been drawn and proposed for design and synthesis of most probable potent antiproliferative synthetic drugs.     

The structure, reproduction and taxonomy of Vidalia and Osmundaria (Rhodophyta, Rhodomelaceae)

Comprises species occurring mostly in subtidal habitats in tropical, subtropical and warm-temperate areas of the world. An analysis of the type species, V. spiralis (Sonder) Lamouroux ex J. Agardh, a species from Australia, establishes basic characters for distinguishing species in the genus. These characters are (1) branching patterns of thalli, (2) flat blades that may be spiralled on their axis, (3) width of the blade, (4) primary or secondary derivation of sterile and fertile branchlets and (5) position of sterile and fertile branchlets on the thalli. Application of the latter two characters provides an important basic method for separation of species into three major groups. Osmundaria , a genus known only in southern Australia, was studied in relation to Vidalia , and its separation from the Vidalia assemblage is not accepted. Species of Vidalia therefore are transferred to the older genus name, Osmundaria. Two new species, Osmundaria papenfussii and Osmundaria oliveae are described from Natal. Confusion in the usage of the epithet, Vidalia fimbriala Brown ex Turner has been clarified, and Vidalia gregaria Falkenberg, described as an epiphyte on Osmundaria pro/ifera Lamouroux, is revealed to be young branches of the host, Osmundaria prolifera.     

New or rare chromosome counts in Artemisia L. (Asteraceae, Anthemideae) and related genera from Kazakhstan

Fifteen chromosome counts of six Artemisia taxa and one species of each of the genera Brachanthemum, Hippolytia, Kaschgaria, Lepidolopsis and Turaniphytum are reported from Kazakhstan. Three of them are new reports, two are not consistent with previous counts and the remainder are confirmations of very scarce (one to four) earlier records. All the populations studied have the same basic chromosome number, x = 9, with ploidy levels ranging from 2x to 6x. Some correlations between ploidy level, morphological characters and distribution are noted.     

肝癌中HBV和HCV基因和抗原的分布及意义

采用原位分子杂交方法检测HCV RNA及HBV X基因;采用免疫组织化学方法研究HCV核心抗原,非结构区C33c抗原及HBxAg在肝细胞肝癌中的定位及分布.结果表明(1)HCV RNA、HBV X基因在肝细胞肝癌组织检出率分别为40%(55/136)和82%(112/136).HCV RNA定位于癌细胞的胞浆内,阳性细胞呈散在、灶状及弥漫分布三种形式;HBV X基因在肝癌细胞中的分布呈胞浆型、核型及核浆型,阳性细胞也呈上述三种分布形式;(2)HCV C33c抗原、核心抗原在肝细胞肝癌中的阳性率为81%(133/164)及86%(141/164).C33c抗原定位于癌细胞及肝细胞的胞浆内;核心抗原既定位于癌细胞核中,又可定位于胞浆中.C33c抗原阳性细胞以灶状分布为主;而核心抗原阳性细     

Comparative morphology of the carpel in the Liliaceae: Hewardieae, Petrosavieae, and Tricyrteae

The young pistils in the melanthioid tribes, Hewardieae, Petrosavieae and Tricyrteae, are uniformly tricarpellate and syncarpous. They lack raphide idioblasts. All are multiovulate, with bitegmic ovules. The Petrosavieae are marked by the presence of septal glands and incomplete syncarpy. Tepals and stamens adhere to the ovary in the Hewardieae and the Petrosavieae but not in the Tricyrteae. Two vascular bundles occur in the stamens of the Hewartlieae and Tricyrtis latifolia. Ventral bundles in the upper part of the ovary of the Hewardieae are continuous with compound septal bundles and placental bundles in the lower part. Putative ventral bundles occur in the alternate position in the Tricyrteae and putative placental bundles in the opposite. position in the Petrosavieae. The dichtomously branched stigma in each carpel of the Tricyrteae is supplied by a bifurcated dorsal bundle.