紫珠的松香烷型二萜成分研究

从紫殊全草的乙醇提取物的氯仿部分中分得5个松香烷型二萜,经光谱数据分别鉴定为脱氢枞酸(1)、7β-羟基-脱氢枞酸(2)、7α-羟基-脱氢枞酸(3)、7-羰基-脱氢枞酸(4)和18-羧基-6,8,11,13-松香烷酸。以上化台物均为首次从该植物中分得。     

裸花紫珠的化学成分

从裸花紫珠(Callicarpa nudiflora Hook.ex Arn.)地上部分的乙醇提取物中分离得到了7个化合物,经波谱分析确定其结构分别为:木犀草苷(1),木犀草素-3'-O-β-D-吡喃葡萄糖苷(2),木犀草素-4'-O-β-D-吡喃葡萄糖苷(3),2α,3α,19α-三羟基-乌索-12-烯-28-酸(4),乌索酸(5),2α-羟基-乌索酸(6)和齐墩果酸(7)。其中化合物2-7为首次从该植物中分离得到。     

Isopimarane-type diterpenoids from Callicarpa macrophylla vahl

Three new isopimarane-type diterpenoids, named callicapene M1 (1), callicapene M2 (2), and callicapene M3 (3), together with four known isopimarane-type diterpenoids (4, 5, 6, 7), were isolated from the Callicarpa macrophylla Vahl. Their structures were elucidated by spectroscopic techniques (IR, UV, MS, 1D, 2D NMR). The isolated compounds 6 and 7 exhibited potent inhibitory activity with inhibition rates of 40.23–46.78% on NO production in LPS-activated RAW 264.7 macrophage cells by using MTT assays.     

Studies on Fish-killing Components of Callicarpa candicans

A fish-killing component, which was named callicarpone, C₂₀H₂₈O₄, m.p. 111°C, ${[\alpha ]}_{\text{D}}^{{23}^{°}}$ ?180° (chloroform) was isolated from the leaf of Callicarpa candicans and was found to have conjugated carbonyl groups, double bond and one hydroxyl group. The toxicity to fish was evaluated to be as strong as rotenone and ten times stronger than sodium pentachlorophenoxide.

It was deduced from the spectral data of callicarpone (I), the tetraol (IV), the chlorohydrin (VII) and the anhydro-diacetyl derivative (II) that I was a tricarbocyclic diterpene having an ene-l,4-dione and an α-hydroxy-isopropyl attached to an oxide ring. The structure of the rearranged product obtained by treatment with sodium carbonate was established to be IX by converting it to 11-methoxy-ferruginol methyl ether. As this rearrangement was assumed to be initiated by proton abstraction by base, the structure I was required for callicarpone to explain the formation of IX.     

The genus Callicarpa (Lamiaceae) on Borneo

The Bornean species of Callicarpa (Lamiaceae) are revised. Twenty three species are recognized: of these, four are described as new ( C. argentii , C. coriacea , C. subaequalis and C. teneriflora ) and two are raised to species level from variety ( C. endertii and C. hispida ). All 23 species described are assessed for World Conservation Union (IUCN) conservation status. Distribution maps and an identification key are provided. The historic confusion between the genera Geunsia and Callicarpa is discussed. Geunsia is included as a synonym of Callicarpa based on the examination of morphological characters and molecular data. Geunsia is suggested to be nested within Callicarpa based on phylogenetic analyses of nuclear ribosomal internal transcribed spacer (nrITS), partial matK and trnD‐T sequences of 30 taxa using maximum parsimony. © 2009 The Linnean Society of London, Botanical Journal of the Linnean Society, 2009, 159 , 416–455.     

广东紫珠中的萜类化合物及其抗炎活性

对岭南药材广东紫珠(Callicarpa kwangtungensis)地上部分进行化学成分研究,得到11个萜类化合物,分别鉴定为sambucunlin A(1)、2α-羟基羽扇豆醇(2)、swinhoeic acid(3)、3β-羟基-乌苏烷-11-烯-13β,28-内酯(4)、蔷薇酸(5)、2α,3β,6β,18β,23-pentahydroxy-olean-12-en-28-oic acid(6)、rel-5-(3S,8S-dihydroxy-1R,5S-dimethyl-7-oxa-6-oxobicyclo-oct-8-yl)-3-methyl-2Z,4E-pentadienoic acid(7)、salvionoside B(8)、齐墩果酸(9)、白桦脂酸(10)和α-香树脂醇(11)。其中,化合物1～4和6～8为首次从该属植物中分离得到。在化学成分分离基础上,进一步选择脂多糖(LPS)诱导的RAW 264.7小鼠巨噬细胞炎症模型进行萜类化合物抗炎活性测试。结果表明:化合物3和9具有显著的抗炎活性,对比结构发现,三萜类化合物(3～6、9和11)抗炎活性优于倍半萜类化合物(7和...     

杜虹花的组织培养与快速繁殖

1 植物名称杜虹花(Callicarpa formosana Rolfe),又称毛将军、灯黄. 2 材料类别顶芽和带侧芽的茎段. 3 培养条件基本培养基为MS.(1)启动培养基:MS 6-BA 1.0 mg·L-1(单位下同) NAA 0.1;(2)增殖培养基:MS 6-BA 0.8 IBA 0.02;(3)壮苗培养基:1/2MS 6-BA 0.2 IBA 0.1:(4)生根培养基:1/2MS IBA 0.2.     

大叶紫珠的组织培养与快速繁殖

1 植物名称 大叶紫珠(Callicarpa macrophylla Vah1),别名大风叶、白狗肠. 2 材料类别 带节茎段. 3 培养条件 (1)芽诱导与增殖培养基:MS+6-BA0.8 mg-L-1(单位下同)+IBA 0.02;(2)生根培养基:1/2MS+IBA 0.05.     

紫珠叶化学成分的镇痛活性研究

目的：研究紫珠叶的镇痛作用。方法：用昆明种小鼠,采用醋酸小鼠扭体法研究紫珠叶提取物及部分成分镇痛作用。结果：紫珠叶粗提物以及部分三萜、黄酮类化合物能显著减少小鼠扭体次数。结论：紫珠叶具有明显的镇痛作用。     

Valid publication of the name Callicarpa peichieniana (Lamiaceae)

‘Callicarpa peichieniana W. Y. Chun & S. L. Chen ex W. Z. Fang’ is a replacement name for Premna peii W. Y. Chun ex H. T. Chang. However, this replacement name was not validly published in 1982 by W. Z. Fang because the reference citation of the replaced synonym P. peii that was published in 1960 was contrary to Article 33.4 of ICBN. The first publication of Premna peii in 1960 was invalid due to lack of type indication, in conflict with Article 37.1, and it was subsequently validated in 1963. In this study, we correct the place of valid publication of P. peii, thereby validating C. peichieniana W. Y. Chun & S. L. Chen ex H. Ma & W. B. Yu.     

Phytotoxicity and volatile constituents from leaves of Callicarpa japonica Thunb

The essential oil from the leaves of Callicarpa japonica was analyzed by GC-MS, and 84 compounds were identified. The main constituents of the essential oil were spathulenol (18.1%), germacrene B (13.0%), bicyclogermacrene (11.0%), globulol (3.3%), viridiflorol (2.6%), alpha-guaiene (2.3%), and gamma-elemene (2.0%). The essential oil constituents of C. japonica were significantly different from those found in our previous work on Callicarpa americana. The oil of C. japonica was selectively phytotoxic to bentgrass compared to lettuce seeds, with 80-100% growth reduction observed at 0.3 mg/ml.     

紫珠耐热抗旱性初步研究

针对武汉地区夏季高温干旱的气候特点,分别在室内人工模拟高温和干旱的条件下,对紫珠的耐热性和抗旱性进行了初步研究。结果表明:紫珠有一定的耐高温干旱能力,能忍受45℃高温连续9天和持续9天的干旱,是一种较好的新型园林节水耐旱观果灌木。     

Validation of the name Callicarpa bodinieri var.iteophylla (Lamiaceae)

Callicarpa bodinieri H.Léveillé var.iteophylla C.Y.Wu,var.nov.Type:China.Yunnan:Mengla,1953-06-03,Yong-Shu Wang 27 (holotype,KUN 0484466!;isotype,KUN 0484467!).Validating diagnosis:Those ofCallicarpa bodinieri H.Léveillé var.iteophylla C.Y.Wu,Fl.Yunnan.1:406.1977.Callicarpa bodinieri H.Léveillé var.iteophylla C.Y.Wu is endemic to southern Yunnan province of China,and it occurs in mixed forests at altitudes between 600 and 1600 m.This new variety is easily distinguished from var.bodinieri and var.rosthornii (Diels)Rehder in that the leaf blade is lanceolate,oblanceolate,or obovateoblong,and 2-4 cm wide (vs.narrowly elliptic,elliptic,or ovateelliptic,and 4-7 cm wide in var.bodinieri),and subglabrous on both surfaces (vs.abaxially grayish stellate pubescent in var.rosthornii).     

Confirmation of the structure of calliterpenone,a diterpene from Callicarpa macrophylla

The structure and absolute configuration of calliterpenone has been established as 3-oxo-13β-kaurane-16α,17-diol. This conclusion confirms that proposed by Ahmad and Zaman, and the formula suggested previously by Chatterjee et al. is revised.     

Isolation and Structure of Maingayic Acid,a Piscicidal Constituent of Callicarpa maingayi

A piscicidal constituent (1), C₂₀H₂₈O₃, (chloroform), which was named maingayic acid, was isolated from the leaf of Callicarpa maingayi. On the basis of the chemical spectral studies, the pK_MCS evaluation and the octant rule on the ORD curves, we have and deduced that maingayic acid is a furanoid diterpene acid possessing a rearranged labdane skeleton shown as 1’a.     

基于UPLC-Q-TOF-MS/MS的裸花紫珠水提物化学成分分析

为了对裸花紫珠水提物的化学成分进行分析鉴定,本研究以加热回流提取法制备裸花紫珠水提物,并采用超高效液相色谱串联四级杆飞行时间质谱法(UPLC-Q-TOF-MS/MS)通过高分辨质谱数据并结合相关文献,分析鉴定水提物的化学成分。最终从裸花紫珠药材水提物中共鉴定出37个化学成分,包括5个黄酮类化合物,16个苯乙醇苷类化合物及16个环烯醚萜类化合物。其中,京尼平苷酸、连翘脂苷E、肉苁蓉苷F为首次从裸花紫珠中报道。并推测木犀草苷、连翘酯苷B、毛蕊花糖苷和异毛蕊花糖苷为裸花紫珠的标志性成分,可为裸花紫珠后续药效物质基础研究及中成药二次开发和质量控制提供参考。