预约挂号平台出票客户端的设计与应用

目的 为预约挂号患者提供出票服务,分流挂号窗口排队人群。方法 设计预约挂号出票客户端,自助服务与人工服务相结合,合理规划业务流程。结果 预约挂号患者不需在挂号窗口排队,可为预约挂号患者提供24小时多地点自助出票服务,同时实现医院对预约挂号第三方支付的财务监管。结论 预约挂号出票客户端极大地方便了患者及医院,具有较好的可行性。     

基于排队论的门诊挂号收费窗口的配置

在国内,总能看到各大医院门诊都排着长长的队,究其原因是因为门诊工作量大,而医疗资源相对有限,当现有的医疗资源无法满足源源不断到来的病患时,就会不可避免的出现排队现象,这其中反映最为突出的就是挂号缴费等待时间长。本文将选取襄阳市某中医医院的实例,应用排队论的数学模型,分析该院门诊收费挂号窗口配置的合理性,为医院科学管理提供理论依据和指导,从而达到缩短患者就诊时间,提高服务满意度的目标。     

基于市民卡、健康卡的自助挂号缴费系统建设

目的 建设全院甚至医院间通用的自助挂号缴费系统，方便患者挂号缴费，获得连续、便捷的医疗卫生服务。方法 利用“市民卡”“健康卡”“银联卡”三卡合一，与医院的HIS相接，提供自助模式的挂号缴费。结果 自助设备终端能完全替代人工挂号收费窗口，同时实现门诊病人的电子健康档案、电子病历等卫生信息资源共享。结论 建立了病人就诊的智能化便捷通道，较好地解决了医院与患者之间的服务矛盾，缓解了患者“看病难”问题。     

门诊退号原因调查分析及管理对策

通过对2007—2010年挂号、退号数据的分析研究,得出导致退号的原因中,医疗资源不足、病患家长不愿意长时间等候是首要原因,其他原因既有病患方面的,也有医院管理方面的。通过对各种原因的综合分析,提出改进医院门诊挂号管理的建议：预约挂号——按时间段实名制预约挂号,错峰门诊,以此促进医疗效率的提高。     

北京某三甲医院预约挂号对患者候诊时间的影响分析

目的 分析预约挂号是否缩短门诊患者的等候时间。方法抽取医院某一周全部患者挂号记录49 147条,通过秩和检验方法,分析预约挂号与非预约挂号患者的候诊时间的差异,比较不同预约方式对患者候诊时间是否存在影响。结果 预约挂号平均候诊时间为50分钟,非预约挂号患者平均候诊时间为111分钟,不同预约方式的患者候诊时间存在统计学上的差异。结论 预约挂号能够有效缩短门诊患者的候诊时间,其中复诊预约患者候诊时间最短,应鼓励患者预约就诊,复诊患者应鼓励进行复诊预约。     

国内医院预约挂号的现状和建议

随着国家医疗改革的不断深入,卫生部针对国内大部分综合性医院门诊挂号拥挤的现象和因此导致的众多问题,推出了预约挂号的新政。预约挂号实行以来减轻了门诊拥挤,提高了诊疗效率,方便了患者就诊,但在实际推广仍有不足,因此需要推广实名制挂号、构建统一预约挂号平台、加强信用建设、完善医院管理创新、试行社区预约转诊等,实现预约挂号的"人性化、精细化、信息化、社会化"。     

北京市42所医院门诊预约挂号现状调查

目的 通过调查医院门诊预约挂号服务的内容、形式、管理模式等情况,为提高医院门诊预约挂号服务质量提供建议。方法 通过对2011—2013年北京市共计42所医院门诊预约挂号服务进行全面统计分析,了解其门诊预约挂号服务现状。 结果 目前北京市预约挂号工作呈现覆盖范围广泛、形式多样的特点;患者预约挂号使用率提高,就医习惯逐渐改变。结论医院应多部门协作,提供完善的配套制度、足够的人力资源等作为保障,推动预约挂号工作进一步发展。     

专家门诊预约挂号影响因素分析

??????? 目的 初步探讨影响专家预约挂号率的原因及相应对策。方法 以SPSS 13.0软件分析2012年4月—2013年1月专家门诊情况与预约挂号率的关系。结果 不同门诊时间（季度、周别、午别）、不同专科、不同专家、不同门诊级别以及挂号率与号源使用率对我院专家门诊预约挂号率均有影响。结论 影响专家门诊预约挂号率的因素是多方面的，需采取综合措施，加强医院核心竞争力才是根本。     

北京某三甲医院预约挂号满意度及影响因素调查

目的 改进医院预约挂号服务工作,完善预约挂号流程,进一步满足患者需求。方法 以2011年6月对通过网络、电话预约挂号的方式成功挂号的患者为调查对象,采用问卷调查方法,由经过培训的调查员进行调查,采用Epidata3.0软件进行数据录入,采用SPSS13.0进行统计分析。结果 对网络、电话预约挂号不满意的有57.4%,不满意的原因主要集中在取号环节上,80%多的患者是通过媒体和医院的宣传知道预约挂号的,但外地患者不足10%。结论 医院试行的网络、电话预约挂号方式具有一定的现实可行性,但是在取号环节及宣传预约挂号的方面,具有一定的欠缺,需要进一步完善和优化。     

“互联网+”背景下医院挂号缴费模式的机遇与挑战

随着“互联网+”的推广及普遍应用,基于互联网的信息技术在医疗服务行业迅速发展。网络预约挂号和移动支付等挂号缴费新模式的推行为解决医院“三长一短”的问题带来了新的契机。通过对“互联网+”背景下医院在挂号、缴费等方面的现状研究,提出了新模式下可能存在的问题及改进建议。

     

Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures

Defects in mitochondrial energy metabolism have been implicated in the pathology of several neurodegenerative disorders. In addition, the reactive metabolites generated from the metabolism and oxidation of the neurotransmitter dopamine (DA) are thought to contribute to the damage to neurons of the basal ganglia. We have previously demonstrated that infusions of the metabolic inhibitor malonate into the striata of mice or rats produce degeneration of DA nerve terminals. In the present studies, we demonstrate that an intrastriatal infusion of malonate induces a substantial increase in DA efflux in awake, behaving mice as measured by in vivo microdialysis. Furthermore, pretreatment of mice with tetrabenazine (TBZ) or the TBZ analogue Ro 4-1284 (Ro-4), compounds that reversibly inhibit the vesicular storage of DA, attenuates the malonate-induced DA efflux as well as the damage to DA nerve terminals. Consistent with these findings, the damage to both DA and GABA neurons in mesencephalic cultures by malonate exposure was attenuated by pretreatment with TBZ or Ro-4. Treatment with these compounds did not affect the formation of free radicals or the inhibition of oxidative phosphorylation resulting from malonate exposure alone. Our data suggest that DA plays an important role in the neurotoxicity produced by malonate. These findings provide direct evidence that inhibition of succinate dehydrogenase causes an increase in extracellular DA levels and indicate that bioenergetic defects may contribute to the pathogenesis of chronic neurodegenerative diseases through a mechanism involving DA.     

Scurvy in capybaras bred in captivity in Argentine

In order to determine if the absence of vitamin C in the diet of capybaras (Hydrochoerus hydrochaeris) causes scurvy, a group of seven young individuals were fed food pellets without ascorbic acid, while another group of eight individuals received the same food with 1 g of ascorbic acid per animal per day. Animals in the first group developed signs of scurvy-like gingivitis, breaking of the incisors and death of one animal. Clinical signs appeared between 25 and 104 days from the beginning of the trial in all individuals. Growth rates of individuals deprived of vitamin C was considerably less than those observed in the control group. Deficiency of ascorbic acid had a severe effect on reproduction of another population of captive capybaras. We found that the decrease in ascorbic acid content in the diet affected pregnancy, especially during the first stages. The results obtained suggest that it is necessary to supply a suitable quantity of vitamin C in the diet of this species in captivity.     

Changes in lactate dehydrogenase activity in chicken tissues in hyperthyreosis in ontogenesis

The lactate dehydrogenase activity in reactions of lactate oxidation and synthesis was studied in subfractions of the chicken brain, heart and liver at the embryonal, early postembryonal and adult stages of development after thyroxine administration. It has been shown that during embryogenesis thyroxine predominantly enhanced the rate of lactate oxidation in the mitochondrial tissues. A marked increase in the lactate synthesis was found in cytoplasm of the adult chicken tissues. Specificity of enzyme activity alterations was detected in the chicken brain during ontogenesis after thyroxine administration.     

SSTR5 ablation in islet results in alterations in glucose homeostasis in mice

Somatostatin (SST) peptide is a potent inhibitor of insulin secretion and its effect is mediated via somatostatin receptor 5 (SSTR5) in the endocrine pancreas. To investigate the consequences of gene ablation of SSTR5 in the mouse pancreas, we have generated a mouse model in which the SSTR5 gene was specifically knocked down in the pancreatic beta cells (betaSSTR5Kd) using the Cre-lox system. Immunohistochemistry analysis showed that SSTR5 gene expression was absent in beta cells at three months of age. At the time of gene ablation, betaSSTR5Kd mice demonstrated glucose intolerance with lack of insulin response and significantly reduced serum insulin levels. Insulin tolerance test demonstrated a significant increase of insulin clearance in vivo at the same age. In vitro studies demonstrated an absence of response to SST-28 stimulation in the betaSSTR5Kd mouse islet, which was associated with a significantly reduced SST expression level in betaSSTR5Kd mice pancreata. In addition, betaSSTR5Kd mice had significantly reduced serum glucose levels and increased serum insulin levels at 12 months of age. Glucose tolerance test at an older age also indicated a persistently higher insulin level in betaSSTR5Kd mice. Further studies of betaSSTR5Kd mice had revealed elevated serum C-peptide levels at both 3 and 12 months of age, suggesting that these mice are capable of producing and releasing insulin to the periphery. These results support the hypothesis that SSTR5 plays a pivotal role in the regulation of insulin secretion in the mouse pancreas.