Effect of arm motion on standing lateral jumps

The role of arm swing in jumping has been examined in numerous studies of standing jumps for height and forward distance, but no prior studies have explored its effect on lateral jumping. The purpose of the present study was to investigate the effect of arm motion on standing lateral jump performance and to examine the biomechanical mechanisms that may explain differences in jump distance. Six participants executed a series of jumps for maximum lateral distance from two in-ground force platforms for two jump cases (free and restricted arms) while an eight-camera, passive-reflector, motion capture system collected 3D position data throughout the movements. Inverse kinematics and dynamics analyses were performed for all jumps using three-dimensional (3D) link models to calculate segment angular velocities, joint moments, joint powers, and joint work. Free arm motion improved standing lateral jump performance by 29% on average. This improvement was due to increased takeoff velocity and improved lateral and vertical positions of the center of gravity (CG) at takeoff and touchdown. Improved velocity and position of the CG at takeoff resulted from a 33% increase in the work done by the body. This increase in work in free arm jumps compared to restricted arm jumps was found in both upper and lower body joints with the largest improvements (>30 J) occurring at the lower back, right hip, and right shoulder.     

Lumbar spine angles and intervertebral disc characteristics with end-range positions in three planes of motion in healthy people using upright MRI

Understanding changes in lumbar spine (LS) angles and intervertebral disc (IVD) behavior in end-range positions in healthy subjects can provide a basis for developing more specific LS models and comparing people with spine pathology. The purposes of this study are to quantify 3D LS angles and changes in IVD characteristics with end-range positions in 3 planes of motion using upright MRI in healthy people, and to determine which intervertebral segments contribute most in each plane of movement. Thirteen people (average age = 24.4 years, range 18–51 years; 9 females; BMI = 22.4 ± 1.8 kg/m²) with no history of low back pain were scanned in an upright MRI in standing, sitting flexion, sitting axial rotation (left, right), prone on elbows, prone extension, and standing lateral bending (left, right). Global and local intervertebral LS angles were measured. Anterior-posterior length of the IVD and location of the nucleus pulposus was measured. For the sagittal plane, lower LS segments contribute most to change in position, and the location of the nucleus pulposus migrated from a more posterior position in sitting flexion to a more anterior position in end-range extension. For lateral bending, the upper LS contributes most to end-range positions. Small degrees of intervertebral rotation (1–2°) across all levels were observed for axial plane positions. There were no systematic changes in IVD characteristics for axial or coronal plane positions.     

Barbell kinematics should not be used to estimate power output applied to the Barbell-and-body system center of mass during lower-body resistance exercise

The aim of this study was to compare measures of power output applied to the center of mass of the barbell and body system (CM) obtained by multiplying ground reaction force (GRF) by (a) the velocity of the barbell; (b) the velocity of the CM derived from three-dimensional (3D) whole-body motion analysis, and (c) the velocity of the CM derived from GRF during lower-body resistance exercise. Ten resistance-trained men performed 3 maximal-effort single back squats with 60% 1 repetition maximum while GRF and whole-body motion were captured using synchronized Kistler force platforms and a Vicon Motus motion analysis system. Repeated measures analysis of variance of time-normalized kinematic and kinetic data obtained using the different methods showed that the barbell was displaced 13.4% (p < 0.05) more than the CM, the velocity of the barbell was 16.1% (p < 0.05) greater than the velocity of the CM, and power applied to the CM obtained by multiplying GRF by the velocity of the barbell was 18.7% (p < 0.05) greater than power applied to the CM obtained by multiplying the force applied to the CM by its resultant velocity. Further, the velocity of the barbell was significantly greater than the velocity of the trunk, upper leg, lower leg, and foot (p < 0.05), indicating that a failure to consider the kinematics of body segments during lower-body resistance exercise can lead to a significant overestimation of power applied to the CM. Strength and conditioning coaches and investigators are urged to obtain measures of power from the force applied to and the velocity of either the barbell (using inverse dynamics) or CM (GRF or 3D motion analysis). Failure to apply these suggestions could result in continued overestimation of CM power, compromising methodological integrity.     

Assessment of hindlimb locomotor strength in spinal cord transected rats through animal-robot contact force

Robotic locomotor training devices have gained popularity in recent years, yet little has been reported regarding contact forces experienced by the subject performing automated locomotor training, particularly in animal models of neurological injury. The purpose of this study was to develop a means for acquiring contact forces between a robotic device and a rodent model of spinal cord injury through instrumentation of a robotic gait training device (the rat stepper) with miniature force/torque sensors. Sensors were placed at each interface between the robot arm and animal's hindlimb and underneath the stepping surface of both hindpaws (four sensors total). Twenty four female, Sprague-Dawley rats received mid-thoracic spinal cord transections as neonates and were included in the study. Of these 24 animals, training began for 18 animals at 21 days of age and continued for four weeks at five min/day, five days/week. The remaining six animals were untrained. Animal-robot contact forces were acquired for trained animals weekly and untrained animals every two weeks while stepping in the robotic device with both 60 and 90% of their body weight supported (BWS). Animals that received training significantly increased the number of weight supported steps over the four week training period. Analysis of raw contact forces revealed significant increases in forward swing and ground reaction forces during this time, and multiple aspects of animal-robot contact forces were significantly correlated with weight bearing stepping. However, when contact forces were normalized to animal body weight, these increasing trends were no longer present. Comparison of trained and untrained animals revealed significant differences in normalized ground reaction forces (both horizontal and vertical) and normalized forward swing force. Finally, both forward swing and ground reaction forces were significantly reduced at 90% BWS when compared to the 60% condition. These results suggest that measurement of animal-robot contact forces using the instrumented rat stepper can provide a sensitive and reliable measure of hindlimb locomotor strength and control of flexor and extensor muscle activity in neurologically impaired animals. Additionally, these measures may be useful as a means to quantify training intensity or dose-related functional outcomes of automated training.     

The effects of the load mass and load position on body sway in supporting a load on the back

We examined the effects of a load's mass and position on body sway during standing with a load on the back. Three healthy male subjects participated in this experiment. The subjects supported loads of 23kg, 33kg, and 43kg on their backs using a carrier frame. They were asked to stand for 75s on a force platform with their eyes open while being as quiet as possible. Time series data of center-of-pressure (COP) were collected at a sampling rate of 50Hz during the last 60s of the 75s standing period. The COP was measured under three conditions in terms of the load position on the frame: lower (close to the hip), middle, and upper (close to the shoulder). All subjects showed that the lower the position of the load, the more anteriorly the mean COP coordinate was located in the anteroposterior (AP) direction, and the smaller the total distance of the COP trajectories became. Regarding carrying the heavier loads, each subject showed a specific tendency in the mean AP coordinate. The three subjects had different physical characteristics in terms of body height and experience at carrying heavy loads. These results suggest that the examintion of the COP in a static posture can help our understanding of individual information on the posture supporting loads and the general positioning of the body.     

Creatinine versus specific gravity-adjusted urinary cadmium concentrations

The aim was to assess how urinary creatinine is affected by age, gender, body size and meat intake, and to determine to what extent such factors might affect the creatinine adjustment of urinary cadmium. The study was based on three Swedish studies: (1) 67 non-smoking women aged 20–50 years (24-h urine samples); (2) 289 men and 434 women aged 16–81 years (spot urine samples); and (3) 98 men and 105 women aged 19–72 years (spot urine samples). The effects of age, body surface area (as an indicator of muscle mass), and meat intake on urinary creatinine and cadmium were analysed using multiple regression analyses. Gender- and age-related variations in urinary creatinine and cadmium adjusted for creatinine or specific gravity were compared by ANOVA or ANCOVA. In the multiple regression analyses, body surface area, gender, age and meat intake were the major determinants of urinary creatinine. Urinary cadmium adjusted for creatinine and specific gravity were also dependent on body size, gender and age. Urinary cadmium adjusted for creatinine was 15–92% higher in women or older individuals than in men or younger individuals. Women or older individuals had –3 to 79% higher urinary cadmium adjusted for specific gravity than men or younger individuals had, and such a difference between gender or age group was less obvious in specific gravity adjustment than in creatinine adjustment. Thus, urinary cadmium adjusted for creatinine is more affected by age, gender, body size and meat intake than is specific gravity adjustment. When comparing individuals or populations with large differences in muscle mass or meat intake, such effects can be especially important. In such studies, specific gravity adjustment seems to be more appropriate.     

Gender bias in the effects of arms and countermovement on jumping performance

The ability to jump high is considered important in a number of sports. It is commonly accepted that the use of the arms and a counter movement increase jump height. In some sport situations (e.g., volley ball block, basketball rebound), athletes may not be able to utilize a counter movement or arm swing. The purpose of this study is to examine gender differences in the contribution of the arm swing and counter movement to vertical jump height. Fifty college students, 25 men (age = 21.4 +/- 1.7 years, height = 182.2 +/- 8 cm, weight = 83.7 +/- 12.4 kg) and 25 women (age = 20.7 +/- 1.6 years, height = 166.7 +/- 6.3 cm, weight = 61.5 +/- 7.0 kg), performed 4 jumping movements: squat jumps with hands on hips (SNA), counter movement jump with hands on hips (CMNA), squat jump with arm swing (SA), and counter movement with arm swing (CMA). Significant differences were found between men's and women's performance, as well as between each type of jump within each gender. A mixed-model analysis of variance detected gender differences with respect to changes in the jumping movement. For both sexes the jumps in order from worst to best were SNA, CMNA, SA, and CMA. Peak power values for men were 4,057, 4,020, 4,644, and 4,747 W, respectively, for the 4 jumps. The female power values were 2,543, 2,445, 2,842, and 2,788 W, respectively, for the 4 jumps. Arms increased jump height more than a counter movement for both genders, with jump heights for men at 29.6, 31, 36, and 38 cm, respectively, and those of women 21, 22, 26, and 27 cm, respectively. Use of the arms was found to increase the jump height of the men significantly more than that of women. Changes in jumping movements affect men and women differently. The greater increase in jump height for the men when using the arm swing could be because of greater upper body strength of men compared with women. This could have applications to training and upper body strength and also to modeling of jumping movements.     

Starting from standing; why step backwards?

At push-off, the mass centre of gravity of the body must be positioned in front of the foot to prevent a somersault. When starting a sprint from out the standing position the use of a step backwards is necessary for maximal acceleration. The aim of the present study was to quantify the positive contribution to push off from a backward step of the leg, which seems to be counterproductive. Ten subjects were instructed to sprint start in three different ways: (a) starting from the standing position just in front of the force platform on the subject's own initiative, (b) starting from the standing position on the force platform with no step backward allowed, and (c) starting out of the starting position with one leg in front of the force platform and the push-off leg on the force platform. A step backwards was observed in 95% of the starts from the standing position. The push-off force was highest in starting type (a), which had the shortest time to build up the push-off force. The results indicate a positive contribution to the force and power from a step backwards. We advocate developing a training program with special attention to the phenomenon step backwards.     

Validity of hand-to-foot measurement of bioimpedance: standing compared with lying position

Objective: To assess the reliability of the standing measurement of hand‐to‐foot bioimpedance compared with measurements made in the lying position. Research Methods and Procedures: In 205 volunteers 6 to 89 years of age, 111 males and 94 females from six ethnic groups, effects of posture, time, and age on hand‐to‐foot resistance were studied over a range of body size. The effect of time in a position on resistance was also recorded in a small subset (n = 10), and repeat measurements over 3 days at the same time of the day were recorded in another subset (n = 12). Results: Lying impedance was consistently higher than standing, with the relationship (resistance lying/resistance standing) for the children (5 to 14 years) being 1.031, progressing to a ratio of 1.016 in those >60 years. The time spent static in either position did change resistance measurements—a decrease of up to 9 Ω (mean 5 Ω, 1.0%) over 10 minutes of standing and an increase of up to 7 Ω (mean 3 Ω, 0.7%) with lying. Discussion: In the field, measurements of hand‐to‐foot bioimpedance can be made in the standing position, and, with appropriate adjustment, previously validated recumbent equations can be used. Given that errors in the measurement of height and weight also affect the reliability of the derivation of body fat from bioelectrical conductance, the errors that may arise from a more practical standing measurement rather than lying are minimal.     

Muscle force and power in obese and overweight children

The study investigated differences in skeletal muscle function between obese and non-obese children using a force platform. Forty obese children and adolescents (age range 8 to 18 years; 21 girls) and 40 age- and sex-matched controls performed two tests: (1) single two-legged jump, a countermovement jump for maximal height; (2) multiple one-legged hopping on the forefoot, a test of maximal force. In the single two-legged jump, obese subjects had higher absolute peak force (1.62 kN vs 1.09 kN) and peak power (2.46 kW vs 2.06 kW), but lower body weight-related peak force (2.10 vs 2.33) and lower peak power per body mass (30.9 W/kg vs 41.6 W/kg). Jump height (29.3 cm vs 37.5 cm) and maximal vertical velocity (1.92 ms(-1) vs 2.31 ms(-1)) were reduced in obese children. In multiple one-legged hopping, obese subjects had 72% and 84% higher absolute peak force on the left and right foot, respectively. However, forces relative to body weight were 24% and 23% lower in the obese group than in the control group. In conclusion, obese children and adolescents have increased muscle force and power. This partly compensates for the effect of high body weight on muscle performance.     

Force–velocity,force–power relationships of bilateral and unilateral leg multi-joint movements in young and elderly women

The present study investigated force–velocity and force–power relationships of bilateral and unilateral knee-hip extension movement in young and elderly women. Twelve healthy young (age, 19–31 yr) and 12 healthy elderly (age, 60–82 yr) women performed bilateral and unilateral knee-hip extension movements on the dynamometer against loads controlled by the servo system. Under the isotonic force condition, force–velocity relationships were measured. The maximum isometric force (F_max), unloaded velocity (V_max) and power output (P_max) of the movements were calculated from extrapolating force–velocity and force–power relationships. F_max and P_max of bilateral and unilateral knee-hip extension movements were 20–30% lower in elderly than in young women. On the other hand, there were no significant differences in V_max between young and elderly women and between bilateral and unilateral movements. Bilateral deficit was larger as the generation of force was larger in both young and elderly women. Also, bilateral deficit of F_max and P_max were not different between young and elderly women. The results were that lower maximum power output of bilateral and unilateral leg multi-joint movements in elderly women did not depend on the intrinsic shortening velocity of muscle action, but largely on reduction in force generating capacity. This suggests the importance of preventing a loss of force generating capacity of muscles during leg multi-joint movements in elderly women.     

Gender bias in jumping kinetics in National Collegiate Athletic Association Division I basketball players

The purposes of this study are to examine gender differences in the contribution of the arm swing to jump height in men and women basketball players and to examine the role of upper-body strength in the contribution of arm swing to jump height. National Collegiate Athletic Association Division I basketball players (men n = 13, women n = 12) performed 4 jumping movements: squat jumps with hands on hips (SNA) and with arm swings (SA) and countermovement jumps with hands on hips and with arm swings (CMA). Differences were found between the jump heights of men and women. Use of the arms increased the jump height of men more than women. Compared with the SNA, the SA allowed an increase of 7 cm (23%) for men and 4 cm (17%) for women. The CMA allowed for an increase of 10 cm (30%) for men and 6 cm (24%) for women. General upper-body strength measures did not correlate strongly with the effect of arms on jumping, but peak power did. As in previous studies, peak power had a high correlation with jumping performance. These results show that the arm swing contributes significantly to jump performance in both men and women basketball players and that strength training for jumping should focus on power production and lifting exercises that are jump specific.     

Effects of a low-intensity conditioning programme on V˙O2max and maximal instantaneous peak power in elderly women

The effects of 12 weeks of a low-intensity general conditioning programme on maximal instantaneous peak power (Wpeak) and maximal oxygen uptake (VO2max) were examined in 20 elderly women. After medical, familiarisation, and ethical procedures, the subjects were randomly divided into either a training and or a control group. The training group [n = 11; mean (SD) age 63.0 (3.1) years] agreed to take part in a 12-week training programme at an exercise intensity kept under 60% of the heart rate reserve for about 60 min, 3 times a week. The control group [n = 9; mean (SD) age 63.5 (3.3) years] did not perform any particular physical training. Before and after the training period, all participants underwent anthropometric measures and a maximal cycling test to exhaustion to measure their VO2max. In addition, Wpeak was determined 1 week later by the subjects performing a vertical jump from a squatting position on a force platform. Following training, neither the anthropometric characteristics nor the VO2max changed in either of the groups. In contrast, Wpeak increased significantly (P < 0.001) in the training group, but did not change in the control group. This result could be interpreted as the result of an improved level of neuromuscular activation. Furthermore, it shows that although muscle power declines with age at a faster rate than does aerobic power, its sensitivity to training seems to be higher than that of the aerobic system.     

Age‐ and Gender‐specific BMI in Terms of the Lowest Mortality in Japanese General Population

Objective: The primary purposes of our study were to establish age‐ and gender‐specific BMIs in terms of lowest mortality (risk nadir BMIs) for the Japanese population, and to then compare those to (i) BMIs for whites as determined by similar studies and to (ii) the official BMI guidelines. Methods and Procedures: A total of 32,060 men and 61,916 women aged 40–79 years underwent health check‐ups in Ibaraki prefecture, Japan, in 1993 and were followed through 2003. To determine the age‐ and gender‐specific risk nadir BMIs, coefficients and the lowest point from a quadratic model with transformed BMI were calculated by a Cox proportional hazard model. This included the quadratic term of 1/BMI and adjusted values (age, alcohol intake, and smoking status). Results: For both age and both gender categories, the relationship between all‐cause mortality risk and BMI categories are illustrated as U‐shaped curves. The risk nadir BMIs for men in the age groups of 40–59 and 60–79 years were 23.4 and 25.3 kg/m², respectively. Similarly, in women, the risk nadir BMIs were 21.6 and 23.4 kg/m², respectively. Discussion: Among the general Japanese population, the risk nadir BMI for the age group of 60–79 years was higher compared to the age group of 40–59 years, which was similar to the study for whites, and the age‐dependent risk nadir BMI differed from the official guidelines criteria. Our findings underscore the importance of weight control following appropriate indicators of body weight according to age.     

Prediction of femoral impact forces in falls on the hip.

A major determinant of the risk of hip fracture in a fall from standing height is the force applied to the femur at impact. This force is determined by the impact velocity of the hip and the effective mass, stiffness, and damping of the body at the moment of contact. We have developed a simple experiment (the pelvis release experiment) to measure the effective stiffness and damping of the body when a step change in force is applied to the lateral aspect of the hip. Results from pelvis release experiments with 14 human subjects suggest that both increased soft tissue thickness over the hip and impacting the ground in a relaxed state can decrease the effective stiffness of the body, and subsequently reduce peak impact forces. Comparison between our fall impact force predictions and in-vitro measures of femoral fracture strength suggest that any fall from standing height producing direct, lateral impact on the greater trochanter can fracture the elderly hip.     

Effects of 20 days horizontal bed rest on maintaining upright standing posture in young persons

The effects of 20 days horizontal bed rest (BR) on postural reflex were studied by measuring fluctuation of center of gravity in the body during two legs or one leg upright standing in 10 young volunteers. The fluctuation was decided as total moving distance of the center recorded during 60sec standing on a force plate. The stability was measured by the moved area. After BR, the moving distance increased during two legs standing with open eyes (p<0.05), but statistically unchanged with closed eyes. The moving area decreased during right one-leg standing with closed eyes (p<0.05), but unchanged during left one-leg standing. Despite with open eyes the increased distance suggested that postural reflexes to maintain upright position were probably decreased by increased unsuitable feedback informations from the visual receptor deconditioning during BR. The decreased area during right one-leg standing with closed eyes also suggested that the declined standing posture reflex was probably related to more rapidly lowered functions for maintaining standing position in the dominating leg than in the other.     

Investigation of optimal follower load path generated by trunk muscle coordination

It has been reported that the center of rotation of each vertebral body is located posterior to the vertebral body center. Moreover, it has been suggested that an optimized follower load (FL) acts posterior to the vertebral body center. However, the optimal position of the FL with respect to typical biomechanical characteristics regarding spinal stabilization, such as joint compressive force, shear force, joint moment, and muscle stress, has not been studied. A variation in the center of rotation of each vertebra was formulated in a three-dimensional finite element model of the lumbar spine with 117 pairs of trunk muscles. Then, the optimal translation of the FL path connecting the centers of rotations was estimated by solving the optimization problem that was to simultaneously minimize the compressive forces, the shear forces, and the joint moments or to minimize the cubic muscle stresses. An upright neutral standing position and a standing position with 200N in both hands were considered. The FL path moved posterior, regardless of the optimization criteria and loading conditions. The FL path moved 5.0 and 7.8mm posterior in upright standing and 4.1mm and 7.0mm posterior in standing with 200N in hands for each optimization scheme. In addition, it was presented that the optimal FL path may have advantages in comparison to the body center FL path. The present techniques may be important in understanding the spine stabilization function of the trunk muscles.     

Human postural responses to different frequency vibrations of lower leg muscles

We analyzed human postural responses to muscle vibration applied at four different frequencies to lower leg muscles, the lateral gastrocnemius (GA) or tibialis anterior (TA) muscles. The muscle vibrations induced changes in postural orientation characterized by the center of pressure (CoP) on the force platform surface on which the subjects were standing. Unilateral vibratory stimulation of TA induced body leaning forward and in the direction of the stimulated leg. Unilateral vibration of GA muscles induced body tilting backwards and in the opposite direction of the stimulated leg. The time course of postural responses was similar and started within 1 s after the onset of vibration by a gradual body tilt. When a new slope of the body position was reached, oscillations of body alignment occurred. When the vibrations were discontinued, this was followed by rapid recovery of the initial body position. The relationship between the magnitude of the postural response and frequency of vibration differed between TA and GA. While the magnitude of postural responses to TA vibration increased approximately linearly in the 60-100 Hz range of vibration frequency, the magnitude of response to GA vibration increased linearly only at lower frequencies of 40-60 Hz. The direction of body tilt induced by muscle vibration did not depend on the vibration frequency.     

Determination of optimal loading during the power clean, in collegiate athletes

ABSTRACT: Comfort, P, Fletcher, C, and McMahon, JJ. Determination of optimal loading during the power clean, in collegiate athletes. J Strength Cond Res 26(11): 2970-2974, 2012-Although previous research has been performed in similar areas of study, the optimal load for the development of peak power during training remains controversial, and this has yet to be established in collegiate level athletes. The purpose of this study was to determine the optimal load to achieve peak power output during the power clean in collegiate athletes. Nineteen male collegiate athletes (age 21.5 ± 1.4 years; height 173.86 ± 7.98 cm; body mass 78.85 ± 8.67 kg) performed 3 repetitions of power cleans, while standing on a force platform, using loads of 30, 40, 50, 60, 70, and 80% of their predetermined 1-repetition maximum (1RM) power clean, in a randomized, counterbalanced order. Peak power output occurred at 70% 1RM (2,951.7 ± 931.71 W), which was significantly greater than the 30% (2,149.5 ± 406.98 W, p = 0.007), 40% (2,201.0 ± 438.82 W, p = 0.04), and 50% (2,231.1 ± 501.09 W, p = 0.05) conditions, although not significantly different when compared with the 60 and 80% 1RM loads. In addition, force increased with an increase in load, with peak force occurring at 80% 1RM (1,939.1 ± 320.97 N), which was significantly greater (p < 0.001) than the 30, 40, 50, and 60% 1RM loads but not significantly greater (p > 0.05) than the 70% 1RM load (1,921.2 ± 345.16 N). In contrast, there was no significant difference (p > 0.05) in rate of force development across loads. When training to maximize force and power, it may be advantageous to use loads equivalent to 60-80% of the 1RM, in collegiate level athletes.     

O‐110 YEAR AUDIT OF GLANDULAR CYTOLOGY REPORTS WITH SPECIAL REGARD TO THE EFFECT OF CONVERSION TO LBC

Objectives: A randomised trial in screening to improve cytology (ARTISTIC Trial) was set up to evaluate the effectiveness of human papilloma virus (HPV) testing in primary cervical screening. Design: Women attending the NHS Cervical Screening Programme in Greater Manchester were screened for HPV in addition to routine cytological testing with ThinPrep Liquid‐Based Cytology (LBC). 25 020 women aged 20–64 were screened at entry and 3 years later. Participants were randomised in a 3 : 1 ratio between those whose HPV test result was revealed and acted upon and those in whom it was concealed. Results: A total of 24 510 women (18 386 revealed and 6124 concealed) had adequate cytology and HPV results. Cytology results at entry were: 87% normal, 11% borderline or mild, 1.1% moderate and 0.6% severe dyskaryosis or worse. Prevalence of HPV decreased sharply with age, from 40% at age 20–24 to 12% at 35–39 and 7% or less above age 50, and increased with cytological grade, from 10% (normal cytology) to 31% (borderline), 70% (mild), 86% (moderate), and 96% (severe or worse). Only 60% of women with severe dyskaryosis showed HPV 16 and / or 18 infection. Conclusion: The ARTISTIC Trial has provided the largest collection of LBC samples with HPV typing in Greater Manchester population. It has shown that the HPV testing is practicable in routine screening in women aged over 30. HPV 16 and 18 are more predictive for underlying disease, but other HPV types account for 30% of high‐grade disease.