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Watt F Martorana A Brookes DE Ho T Kingsley E O'Keefe DS Russell PJ Heston WD Molloy PL 《Genomics》2001,73(3):243-254
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PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression 总被引：16，自引：0，他引：16
Oettgen P Finger E Sun Z Akbarali Y Thamrongsak U Boltax J Grall F Dube A Weiss A Brown L Quinn G Kas K Endress G Kunsch C Libermann TA 《The Journal of biological chemistry》2000,275(2):1216-1225
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The Effects of the Organic Flame‐Retardant 1,2‐Dibromo‐4‐(1,2‐dibromoethyl) Cyclohexane (TBECH) on Androgen Signaling in Human Prostate Cancer Cell Lines 
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下载免费PDF全文 Lilian I. L. Wong Alexandra R. Reers Heidi A. Currier Tony D. Williams Michael E. Cox John E. Elliott Timothy V. Beischlag 《Journal of biochemical and molecular toxicology》2016,30(5):239-242
The effects of the organic flame retardant 1,2‐Dibromo‐4‐(1,2‐dibromoethyl) cyclohexane (TBECH) on androgen receptor target gene expression were examined in the human LNCaP prostate cancer cell line. While γ‐/δ‐TBECH alone led to a significant increase in prostate‐specific antigen (PSA) mRNA accumulation, both the α‐/‐TBECH and γ‐/δ‐TBECH mixtures repressed androgen‐inducible PSA mRNA and protein accumulation in human LNCaP cells. Thus, we hypothesize that isomeric mixtures of TBECH may act as partial agonists of the androgen receptor. 相似文献