相反相成药物治疗马骡结症的理论探讨

“对立统一规律是宇宙的根本规律。”动物体是完整统一的有机体,其各系统、各器官的机能活动是矛盾的,对立的,同时又是统一的。心脏的跳动,肺脏的呼吸,肌肉的伸缩,胃肠的蠕动等,都是由相互联系、相互制约的对立统一的活动完成的。在这些活动当中,神经系统起着主要的调节作用。中枢神经系统是支配全身活动的中枢,而内脏器官的活动是由相对自主的植     

学案导学在高中生物教学中的应用

制作学案的过程,就是老师理解通透所传授的知识的前提下,阅读大量的相关的资料,根据学生的认知水平与知识的积累能力,为指导学生进行主动的知识建构而编制的学习方案,以便积极引导和帮助学生的自主学习的能力进行探究思索的方案。高中生物的教学研究问题,通过学案的方式向学生传授知识,是教师在教学理论与学习标准的指导下对高中生物的教学所提高的一个新层次。     

植物保护与农业可持续发展关系探究

随着社会的发展经济的进步我国在各个领域的发展上都得到了相应的提升,从农业的发展情况来看,由于我国在科学技术上进步故此在农业的发展上也取得了重大的成效,但是在农业发展的过程中也出现了一些严重的问题,就是对于化学药品的使用所造成的农产品的污染以及环境的污染。本文主要针对当前的一些植物保护的现状进行阐述,并对植物保护和农业的可持续发展间的关系进行了详细的分析探究,希望能够在此领域的学术发展起到一定的参考作用。     

自然和热凝固的人肝组织对KTP/YAG激光的光学特性的比较研究

本文采用双积分球测量系统和Inverse Add ing-Doub ling方法,研究了自然和热凝固的人肝组织对532nm的KTP激光和1 064 nm的Nd:YAG激光的光学特性。结果表明:热凝固的人肝组织对532 nm的KTP激光的吸收系数较自然的肝组织的吸收系数增大了23.5%(P<0.05),热凝固的肝组织对1 064 nm的Nd:YAG激光的吸收系数较自然的肝组织的吸收系数减小了34.3%(P<0.05)。热凝固的人肝组织对532 nm的KTP激光的散射系数较自然的肝组织的散射系数增大了4.50倍(P<0.05),热凝固的肝组织对1 064 nm的Nd:YAG激光的散射系数较自然的肝组织的散射系数增大了6.41倍(P<0.05)。热凝固的人肝组织对532 nm的KTP激光的各向异性因子较自然的肝组织的各向异性因子减小了5.47%,热凝固的肝组织对1 064 nm的Nd:YAG激光的各向异性因子较自然的肝组织的各向异性因子减小了1.95%。     

浅析如何做好基层林业站的工作

在当前的形势下,我国的林业建设工作也是需要及时的调整发展方案,以此来适应新时代的发展的,要由传统的林业建设模式逐渐的向现代化的方向发展。从某种程度上来说,基层林业站的微观变化也会对林业建设的发展方向的宏观调整产生直接的影响,因此,要结合科学发展的建设理念,来指导林业站的工作,以此来促进林业的健康建设。文章主要阐述基层林业站的作用,主要是为更好的发挥基层林业站的效用服务的。     

植物生理学研究与四化建设

一、植物生理学面临的挑战作为植物学的一个重要分支的植物生理学经过百余年的发展对植物生命活动的基本规律及其与环境的关系的了解取得了长足的进展,也对人类的生产活动起了巨大的促进作用。例如化学肥料及生长调节剂与除草剂的大规模应用,细胞全能性的发现及利用等。但与现代自然科学体系日新月异的进步相比植物生理学则象百舸竞渡中的一叶扁舟,面临着严峻的挑战。近年分子生物学和遗传学的飞速进步,各种物理化学检测手段的应用及检测精度的提高,使植物生理学的机理的探索必须建立在分子生物学的基础上并相应地使用精确的检测手段,例如植物激素乙烯的发现及其生物合成与作用机理的研究,就是建     

云南一些植物特征成分与古夷平面的相关性

生理生态学的原则是随着纬度的升高,物种分布的海拔高度将随之降低。但是,云南一些植物特征成分的分布却与之相反,它们的分布与云南残留的古夷平面的分布相似,即随着纬度的升高,其分布的海拔高度也随之升高。二者的区别是云南古夷平面分布的趋势线的仰角大于那些特征成分分布的趋势线的仰角。可能的原因是：相对于剧烈的地质运动,物种的适应能力总是相对滞后的,并且物种的分布也受到其生长特性的制约;根据分布区形成的原则,这些成分的发生应早于夷平面的隆起。     

探讨中日环境管理存在的差异以及解决对策

环境状况的好与坏通常决定着一个国家的综合国力的强与弱。近几年来,随着社会的发展,环境方面的问题越来越多,各个国家对于环境问题的解决方法以及管理方式各有千秋,同时各个国家对于环境问题的管理也都十分的重视。而其中,日本环境的管理是开始于20世纪中期的,从20世纪中期到现在,短短的这一段时间中,日本的环境管理出现出人意料的成功,不仅创造了防治产业污染的奇迹,同时也形成了一套相对完成的管理体制以及丰富多彩的管理模式。与日本不同的是,我国的环境管理方面尚且存在一定的问题。本文将结合中日环境管理方面存在的差异探讨中国的环境管理存在的问题的解决对策。     

正常微生物群是一个新的人体生理学系统

1　前言微生态学的发展 ,现在已把微生物的作用 ,从主要是致病作用的观点转移到主要是生理作用的观点。这种观点的转变是经过 10 0多年的学术研究和科学发展才取得的。在 2 0世纪经过无菌动物的饲养、厌氧培养技术的进步和现代分子生物学、基因工程学的研究终于完成了微生态学向新的更高阶段的转变。这就是微生物的研究以致病性为主的时代转向以生理性为主的时代。要确定一门新学科的诞生日期是很难的。一门新学科的定义也是逐渐形成的 ,要经过科研成果不断积累才能逐渐完善。正常微生物群的生理作用的提出是很早的 ,至少要推衍到 19世纪的…     

论物种的客观真实性

关于物种的概念和本质的争论由来已久。大多数学者认为种是自然界客观存在的真实单位,是形态上和生殖上间断的群体体系,与种内连续的群体体系——宗,有着本质的区别。少数学者则认为种是主观意识的产物,是为了分类的目的而任意确定的人为的分类阶元,与宗只有程度的不同而无本质的区别;只有个体才是客观真实的单位。以形态标准为主的分类学种概念和以生殖隔离为标准的生物学种概念只能说代表了自然界有机体类群不连续性的两个不尽相符,但部分一致的侧面,而不能说就是客观物种的反映。自然界的生命有机体有两重性。它们既不是一群乱七八糟的乌合之众,也不是秩然不紊的鳞次栉比,而是以群体的组织形式适应于各自分布区内的生态位,在表型和基因型的变异式样上具有一定规律的遗传多样性。物种的客观本质也有两重性。物种作为有机体组合的单位既存在又不存在。说物种客观存在是因为按形态或生殖的不连续性标准划分的“种”在自然界具有一定的普遍性;说物种并非客观存在是因为至今还没有一个能把所有的生命有机体都划分成统一的生物学单位的不连续性标准。     

The characteristics of the anxiolytic action of benzodiazepine and non-benzodiazepine tranquilizers in different tests of anxiety]

In experiments on rats the presence or absence was studied of the phenomenon of potentiation of anxiolytic action, estimated by the time of the animal stay in the light part of the chamber in tests of avoidance of "the lighted ground" or "menacing situation" at combined application of the pairs of substances of benzodiasepine and non-benzodiasepine series (elenium, indoter, campiron and campironin). Spectra of their neurochemical activity were determined in experiments on neurones of isolated spinal ganglia of rats with intracellular biopotentials records. It has been established that GABA-potentiating action of indoter and elenium, dopamine-negative action of campiron and campironin are significant in their anxiolytic action in the states of alarm of aversive genesis of different modalities. Serotoninmimetic effect of non-diasepine tranquilizers is of functional significance in the test of avoidance of "the lighted ground", but not of the "menacing situation". It is suggested that differences of neurochemical mechanisms of anxiolytic action of the tested tranquilizers testify to different neurochemical profiles of the neuronal "matrices" of the studied states of alarm.     

Study of role of inhibitory interneurons in mechanisms of regulation of sensory synapses formed by thalamic and cortical inputs on pyramidal cells of the dorsolateral amygdala nucleus

The work deals with study of role of inhibitory interneurons in the process of regulation of sensory currents converging on soma of pyramidal cells of the dorsolateral amygdala nucleus as well as of role of these interneurons in mechanism of regulation of plasticity of amygdala synapses. It has been shown that the part of the spontaneous inhibitory postsynaptic currents recorded on the dorsolateral amygdala pyramidal cells is relatively high and amounts to about a half of the total amount of the recorded events. Analysis of the evoked postsynaptic responses has shown the interneurons to regulate activity and duration of these responses due to the postsynaptic membrane hyperpolarization as a result of activation of GABA_A-receptors. Also studied was role of interneurons in providing mechanisms of the long-term potentiation of the synaptic responses evoked by stimulation of cortical and thalamic inputs. Block of effect of interneurons with help of picrotoxin has been shown to lead to an increase of evoked potentiation of synaptic responses.     

The functional testing of the interhemispheric asymmetry in the spatial organization of rabbit cortical potentials]

Interhemispheric asymmetry was studied of spatial-temporal potentials organization (STPO) of the cortex in non-fixated animals in the states of deep rest, behavioural activity and in the transition period between them. Despite the intrahemispheric differences of the STPO in each of these states, interhemispheric divergences in the character of reconstructions of momentary topograms of the cortical potentials, recorded at 24-channels leading, are limited by 35% of the epoch analysis time. Comparison of the dynamics of intrahemispheric changes of topograms of cortical potentials in the left and right hemispheres in the states of rest and activity revealed a narrowing of temporal period of the absence of resemblance in reconstructions of successive topograms of the left and right hemispheres in comparison with transition processes. In the phase of rest the interhemispheric conjugation of spatial reconstructions in topograms became lowered mainly because of the disturbances of monotony of changes of their reliefs in one of the hemispheres in turn. In the active phase, deviations from STPO of the cortex, characteristic of the state of rest, were met more frequently in the right hemisphere; in that case oscillations of the topograms general mean level connected with the activity of non-specific activating subcortical brain system acquired a significant role in regulation of interhemispheric relations. Presence of interhemispheric resemblance of reconstructions of topograms reliefs in the active phase, despite the tendency to its lowering in comparison with the rest, testifies to the contribution also of the intracortical processes to the interhemispheric spatial synchronization of the cortical potentials in this state.     

Conditioning of inhibition of sympathetic nerve discharge to stimulation of A- and C-fibres in the aortic nerve

Stimulation of either A- or C-fibres in the aortic nerve inhibits sympathetic nerve discharge (SND) recorded from the renal nerve in rabbits anaesthetized with urethane. When the test inhibition of SND to stimulation of A-fibres is preceded by conditioning stimulation of the same afferents, the test response is depressed at shorter and facilitated at longer testing intervals. Facilitation of the inhibition of SND reaches 120% of control at a testing interval of 10 s. The recovery curve of inhibition of SND to activation of A-fibres has a time course of 17 s. Following conditioning activation only depression of the test inhibition of SND to stimulation of C-fibres is seen. It reaches 46% of control at an interval of 2 s and the recovery curve of inhibition of SND to stimulation of C-fibres has a time course of about 30 s. In other series of experiments the duration of the conditioning stimulation was varied while the testing intervals were fixed. At a testing interval of 2 s the reductions of the test responses are deeper and the durations of conditioning at which plateaus of depression are reached are longer with stimulation of C- than of A-fibres. Taken together with a longer recovery curve these findings suggest a more effective control of the test inhibition of SND by C-fibres. Opposite changes in the patterns of inhibition of SND to activation of either A- or C-fibres are explained by frequency-dependent post-tetanic effects of the conditioning stimulation.     

The effect of the level of consciousness on the spatial organization of cortical activity in mental processes

In the present study the influence of the level of consciousness on spatial organization of the cortical functional activity in human psychic processes was investigated. For regulation of the level of consciousness models were used of hypnotic analgesia, automatization of intellectual actions and mental activity in hypnotic state. Evaluation of the mosaic of the cortical activity was made by parameters of spatial synchronization of the potentials with topographic mapping of crosscorrelation, spectral and coherent-phasic EEG characteristics. The obtained data allow to conclude about special role of the frontal areas of the left hemisphere in the process of realization of information. It has been shown that one of the main functions in neurophysiological structure of consciousness is the selection of signals according to dominating motivation. The frontal areas of the left hemisphere control the degree of inclusion of foci of increased activity, specific and non-specific for each type of activity, and possibly, regulate the way of transformation of the information.     

Demonstration of the synthesis of hydrocarbons in animal tissues

Incubation of tissue of homogenates of peripheral nerves, liver, and subcutaneous adipose tissue of rabbits with [1-14C]palmitic acid and intraperitoneal injection of this preparation into rats, in a dose of 20 muCi per 100 g of weight of the animals, permitted establishment of the presence of enzyme systems of biosynthesis of n-alkanes in the tissues of higher animals. Evidence of the biosynthesis of n-alkanes in the animal organism represents a new aspect of our knowledge of the metabolism of this class of compounds in animal tissues.     

Cooperative properties of D-glyceraldehyde-3-phosphate dehydrogenase]

The structure of the active center of glyceraldehyde-3-phosphate dehydrogenase and the arrangement of subunits in the tetrameric molecule is delineated. The mechanism of cooperative effects in the oligomer is considered, and the involvement of various regions of the active center and of different-subunit contact area in the realization of the cooperative phenomena is discussed. A special attention is paid to the effect of NAD+ bound to one of the subunits of the tetramer on the structure of an adjacent subunit and to the problem of the participation of the coenzyme in the creation of anion-binding sites of the enzyme. The conditions of reversible dissociation of the tetrameric apoenzyme molecule into dimers are depicted, and the role of NAD+ in the organization of the quaternary structure of the dehydrogenase is discussed. The problem of catalytic activity of the dimeric form of the enzyme is argued.     

Immunoenzyme analysis of the change in the expression of class II antigens of the major histocompatibility complex under the influence of interferon preparations

The interferons (IFN's) are natural regulators of the immune response. This quality of IFN depends to a large extent on their capacity to change the expression of the antigens of the second (II) class of the Major Histocompatibility Complex. The most effective modulator of the expression of the antigens of the class II MHC is beta-IFN. The aim of this work is to explore with the aid of enzyme-linked immunosorbent assay (ELISA) peculiarities of an action of the preparations alpha- and beta-IFN's of a man on the expression of the antigens of the second class on macrophages of mice with using monoclonal antibodies to the products of subregions I-A and I-E MHC. As a result of exploration we have the following: both preparations IFN's (leukinterferon and beta-IFN) reinforce the expression of the antigens of the second class on the macrophages of mice spleens. With combined influence preparation alpha-IFN and beta-IFN show interweakened effect on the expression of the antigens of the class MHC. Exposed regularities of the expression have the same type for products of subregions I-A and I-E H-2 of mice complex. ELISA is the sensible method of determination of a level of the expression of the antigens of the class II MHC on the cell's populations.     

Reflection of the plastic properties of 2 neurons with a common monosynaptic input in the statistical characteristics of their impulse activity

Changes of cross-correlation histograms (CCH) of impulse trains and of mean interspike intervals (ISI) of neurones N1 and N2 with a common monosynaptic excitatory or inhibitory-excitatory input from N3, at changes of efficiency of interneuronal connections, neurone excitability and summate action on them of independent random afferent synaptic inflows were studied by methods of mathematical and biomathematical modelling of neuronal interaction. It was shown that the increase of amplitude of the central peak (trough) of a normalized CCH of N1-N2 accompanied by reduction of mean ISI of N1 and N2, is either a sign of an increase of the amplitude of postsynaptic potentials of N1 and N2 elicited by impulses of the nonrecorded N3 or a sign of an increase of mean ISI of N3.