Register now for the ISN/ASN Biennial Meeting ( http://www.isn-asncancun2013.org ) in Cancun, Mexico! Fees include conference materials, free WiFi at the conference site, lunch and refreshments, as well as a closing fiesta.The list of speakers includes among others Huda Y. Zoghbi, Robin Franklin, Nancy Yuk‐Yu IP, Martin Cammarota, and Hideyuki Okano. Posters will be available for two full days, ensuring that attendees will be able to see the presentations that interest them and that their work will be seen by all of our colleagues. Register now! Further information about the meeting and links for registration may be found on the official website: http://www.isn-asncancun2013.org
During the ISN/ASN meeting in Cancun, ISN President Phil Beart, who has provided an outstanding contribution to the ISN over the last 8 years will also hand over the role to the new incoming President, Alois Saria.
NEW in 2013: 2‐year membership of the ISN is now discounted to $95USD – renew today and save $25USD, or renew your annual membership for $60USD: www.neurochemistry.org/membership/renewmembership.html
Membership and global outreach of the ISN continue: Since the last Biennial meeting in Athens in 2011, the ISN has 552 new members (as of December 2012), of which 317 are students. Welcome to the Society!
Registration of the ISN was moved from the UK (ISN (Ltd)) to the USA (ISN Inc) to ease accounting, which went smoothly thanks to joint efforts and close collaboration of all parties involved.
The 5th ISN Special Conference on ‘Synapses and dendritic spines in health and disease’, held in Buenos Aires, Argentina, has been a great success. A mini review series summarizing major relevant topics covered was solicited, scheduled for publication in early 2013.
New! ISN CAEN “Return Home Grant” aimed at funding research and set‐up supplies (up to $10,000USD) for an applicant who is moving to a country with limited research financial support after a postdoctoral fellowship in a developed country. Please see www.neurochemistry.org/grants-awards/committee-for-aid-and-education-in-neurochemistry-caen.html for additional application details.
New reduced open access fees for JNC publications available only for ISN members ISN members in good standing ($1,000USD).
The 2014 Nobel Prize in Chemistry has been awarded to Stefan W. Hell, Eric Betzig and William E. Moerner for the development of a superresolution imaging technique, STED (stimulated emission depletion). The technique opens up new possibilities in imaging nanostructures, and has been featured in a review article in the Journal of Neurochemistry, entitled “STED microscopy of living cells ‐ new frontiers in membrane and neurobiology” by Christian Eggeling, Kathrin I. Willig and Francisco J. Barrantes: http://onlinelibrary.wiley.com/doi/10.1111/jnc.12243/abstract
A Virtual Issue on Neuroinflammation in Nervous System Disorders: Diversity in Insults and Outcomes, edited by Deputy Chief Editor Tammy Kielian ( http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1471-4159/homepage/virtual_issues.htm#neuroinflammation ), will shortly be followed by a Special Issue on neuroinflammation.
The Journal of Neurochemistry now has a new page for special Article Series and/or reviews solicited at ISN meetings such as the 5th Special ISN Conference 2012 .
The Committee for Aid and Education in Neurochemistry ( CAEN ) provides funds for travelling to another laboratory to develop new technical or conceptual expertise, purchasing research supplies, attending workshops/training courses/satellite meetings or organizing a workshop/small school. The ISN‐CAEN application deadlines for this year are on April 30, August 31 and December 31.
We are very sad that the ISN lost its President Kazuhiro Ikenaka, Professor and Chairman at National Institute for Physiological Sciences (NIPS), Director of Okazaki Institute of Integrative Biology. JNeurochem published an Obituary to value his outstanding achievements: Akio Wanaka et al. (2019) OBITUARY Kazuhiro Ikenaka (1952‐2018). https://doi.org/10.1111/jnc.14679
Abstract We report a cost efficient approach for amino-acid-type selective isotope labeling of proteins expressed in Leishmania tarentolae. The method provides an economically advantageous alternative to recently established protocol for isotopic labeling using expensive synthetic media. The method is based on cultivation of the L. tarentolae expression strain in a cheap complex medium supplemented with labeled amino acid(s). In this protocol, a labeled amino acid is deliberately diluted in the medium of undefined composition, which leads to a low-level isotope enrichment upon protein over-expression. The economic advantage of the protocol is achieved by avoiding large volumes of expensive synthetic medium. Decreased sensitivity of a NMR experiment due to low-level isotope enrichment is compensated by a five- to seven-fold increase of the yield of the recombinant protein in complex medium as compared to that in the synthetic medium. In addition, the decreased sensitivity can be compensated by using a higher magnetic field, cryo-detection system or higher number of transients during the NMR data acquisition. We show that enrichment as low as 5% does not compromise a NMR experiment and makes preparation of the recombinant proteins over- expressed in L. tarentolae economically viable. The method is demonstrated by selective labeling of the ～27 kDa enhanced green fluorescent protein (EGFP) with 15N-labeled valine. 相似文献
