Menarche in Newcastle upon Tyne girls

Using data for 699 white girls from Newcastle upon Tyne, England, who were born in 1962, the authors examine the relationship between age at menarche and selected social and anthropometric variables. Factors considered include family size, birth order, father's occupation, birth weight, and height and weight at five years of age and at menarche (SUMMARY IN FRE, GER)     

Differences in nutritional status between rural and urban Yucatec Maya children: The importance of early life conditions

Early-life conditions shape childhood growth and are affected by urbanization and the nutritional transition. To investigate how early-life conditions (across the “first” and “second” 1000 days) are associated with rural and urban children's nutritional status, we analyzed anthropometric data from Maya children in Yucatan, Mexico. We collected weight, height and triceps skinfold measures, then computed body mass and fat mass indices (BMI/FMI), in a cross-sectional sample of 6-year-olds (urban n = 72, rural n = 66). Demographic, socioeconomic and early-life variables (birthweight/mode, rural/urban residence, household crowding) were collected by maternal interview. We statistically analyzed rural-urban differences in demographic, socioeconomic, early-life, and anthropometric variables, then created linear mixed models to evaluate associations between early-life variables and child anthropometric outcomes. Two-way interactions were tested between early-life variables and child sex, and between early-life variables and rural-urban residence. Results showed that rural children were shorter-statured, with lower overweight/obesity and cesarean delivery rates, compared to urban children. Household crowding was a negative predictor of anthropometric outcomes; the strongest effect was in boys and in urban children. Birthweight positively predicted anthropometric outcomes, especially weight/BMI. Birth mode was positively (not statistically) associated with any anthropometric outcome. Cesarean delivery was more common in boys than in girls, and predicted increased height in urban boys. In conclusion, urbanization and household crowding were the most powerful predictors of Maya 6-year-old anthropometry. The negative effects of crowding may disproportionately affect Maya boys versus girls and urban versus rural children. Early-life conditions shape Maya children's nutritional status both in the “first” and “second” 1000 days.     

Socioeconomic determinants of menarche in rural Polish girls using the decision trees method

The aim of this study was to assess the usefulness of the decision trees method as a research method of multidimensional associations between menarche and socioeconomic variables. The article is based on data collected from the rural area of Choszczno in the West Pomerania district of Poland between 1987 and 2001. Girls were asked about the appearance of first menstruation (a yes/no method). The average menarchal age was estimated by the probit analysis method, using second grade polynomials. The socioeconomic status of the girls' families was determined using five qualitative variables: fathers' and mothers' educational level, source of income, household appliances and the number of children in a family. For classification based on five socioeconomic variables, one of the most effective algorithms CART (Classification and Regression Trees) was used. In 2001 the menarchal age in 66% of examined girls was properly classified, while a higher efficiency of 70% was obtained for girls examined in 1987. The decision trees method enabled the definition of the hierarchy of socioeconomic variables influencing girls' biological development level. The strongest discriminatory power was attributed to the number of children in a family, and the mother's and then father's educational level. Using this method it is possible to detect differences in strength of socioeconomic variables associated with girls' pubescence before 1987 and after 2001 during the transformation of the economic and political systems in Poland. However, the decision trees method is infrequently applied in social sciences and constitutes a novelty; this article proves its usefulness in examining relations between biological processes and a population's living conditions.     

Age trends in anthropometric characteristics among 6-9 years old Bengalee Hindu school girls of Kolkata, India

A cross-sectional study of 431 6-9 years old urban Bengalee Hindu schoolgirls of Kolkata, India, was undertaken to study age trends in anthropometric characteristics including regional and subcutaneous adiposity. The anthropometric variables measured included height, weight, sitting height (SH), waist (WC), hip (HPC), thigh (TC), mid-upper arm (MUAC) and medial calf (MC) circumferences as well as triceps (TSF), biceps (BSF), subscapular SUBSF), suprailliac (SUPSF) and medial calf (MCASF) skinfolds. The results revealed, that there was a significant increasing age trend for all the anthropometric variables including the two derived variables: body mass index (BMI) and subischial leg length (SLL). For all variables, the lowest and the highest means were observed at the age of 6 and 9 years, respectively. The maximum increase in weight, BMI, all linear measurements, WC and HPC were observed during the period 6-7 years of age. In general, all skinfolds recorded similar yearly increments. More importantly, this study clearly indicated that among Bengalee girls aged 6-9 years, the highest amount of linear growth (height, SH and SLL) was observed at 6 years of age. The overall adiposity (BMI) also recorded the maximum increment during this period. The unique data presented here can be used as reference values for urban Bengalee Hindu girls aged 6-9 years.     

Size and shape modifications in Sardinian adolescent girls

In females, menarche is the defining moment of puberty, the period of life when the greatest body changes occur. In the present study, the metric and morphological variations associated with sexual maturation are defined in 155 Sardinian girls (10-17 years) and the role of some potentially influential variables is discussed: age, age at menarche and time since menarche. We studied thirty-eight anthropometric variables, the fat-free mass and the fat mass estimated by Bioelectrical Impedance Analysis. Statistical analyses were performed to evaluate the difference between pre- and post-menarcheal girls of the same age (Student's t-test) and to evaluate the different role played by the variables (principal components analysis, cluster analysis, multiple regression). The results demonstrate that the body dimensions of the adolescent girls mainly increase in concomitance with sexual maturation. The age at menarche influences the fat mass but not the distribution of visceral and subcutaneous fat. The time since menarche has also no effect on the distribution of subcutaneous fat.     

Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls

Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a predictor of health. Pubertal timing has similarly been associated with cancer risk and mortality rate among females. We examined the association between AgeAccel and pubertal timing and adolescent breast composition in the longitudinal Growth and Obesity Cohort Study. AgeAccel was estimated in whole blood using the Horvath method at breast Tanner 2 (B2) and 4 (B4). Total breast volume, absolute fibro-glandular volume (FGV), and %FGV were evaluated at B4 using dual X-ray absorptiometry. The impact of AgeAccel (mean: 0; SD: 3.78) across puberty on the time to breast development (thelarche), menarche, and pubertal tempo (thelarche to menarche) was estimated using accelerated failure time models; generalized estimating equations were used to evaluate associations with breast density. A five-year increase in average adolescent AgeAccel was associated with a significant decrease in time to menarche [hazard ratio (HR): 1.37; 95% confidence interval (CI): 1.04, 1.80] adjusting for birth weight, maternal pre-pregnancy body mass index, maternal height, maternal education, B2 height, fat percentage, and cell composition. AgeAccel displayed a stronger inverse association with pubertal tempo (HR: 1.48; 95% CI: 1.10, 1.99). A five-year increase in AgeAccel was associated with 5% greater %FGV, adjusting for B4 percent body fat, and maternal traits (95% CI: 1.01, 1.10). Our study provides unique insight into the influence of AgeAccel on pubertal development in girls, which may have implications for adult health.     

Correlates and predictors of the age of menarche

In a cross-sectional study of 452 girls between 10 and 16 years of age 36 indices of physical and 50 of mental development were tested for their correlation with age at menarche and chronological age, as well as for their predictive power for estimating menarche by multiple regression analysis. Indices of physical maturity and body weight when adjusted for chronological age showed the highest partial correlation coefficients with age at menarche. Among mental characters which show lower intercorrelations with menarche occurred the highest correlation coefficients for a handmotor factor "Spurennachzeichnen" and a factor "Gruppenabh?ngigkeit" (which indicates a type of social motivation). In general physical and mental factors correlate higher with chronological age than with age at menarche. By multiple regression analysis we determined 14 physical and 25 mental predictors explaining 21% and 17% respectively of the variance of age at menarche. The error of the estimate predicting menarche on body weight without knowledge of onset of menarche is +/- 1 year. Using chronological age in a sample of girls before menarche the error of the estimate only is +/- 6 months. To compare the predictive power of chronological age combined with body weight or with skeletal age the time interval is calculated within which 95% of girls attain menarche. The range of prediction extends from 4.3 to 1 year on chronological age (11-16 years); using mean body weight it can be improved by 1.8 to 6 months, while using mean skeletal age an improvement of 0.2 to 3.9 months is possible compared with body weight. The correlations between age at menarche and physical and mental variables are attributed to a common hormonal influence on rate of development.     

Predictors of age at menarche in the newcastle thousand families study

Several studies have found relationships between early life factors (birth weight, length of gestation, height, weight, duration of breast-feeding, maternal age, social class, periods of infection, presence of adverse life events, and quality of housing conditions in childhood) and age at menarche but none has considered all of these factors in the same study. The follow-up study of the Newcastle Thousand Families birth cohort, established in 1947, provided age at menarche data collected retrospectively at age 50 from 276 women who returned self-completion questionnaires in 1997. Three main independent associations were observed: girls who experienced a shorter gestation, girls whose mothers were younger when they were born, and girls who were heavier at age 9 had earlier menarche. Birth weight, standardized for gestational age, was found to have different relationships with age at menarche depending upon how heavy or light a girl was at age 9. The results of this study support the hypotheses that conditions in fetal and early life are associated with the timing of menarche and that greater childhood growth is associated with earlier menarche. It is suggested that future work should focus on illuminating the mechanisms underlying these statistical relationships.     

Gender-specific growth patterns for stature,sitting height and limbs length in Croatian children and youth (3 to 18 years of age)

In a cross-sectional study of growth, 5,155 children (2,591 females, 2,564 males) from the town of Zagreb (Croatia) were measured. Four traits of linear dimensionality (stature, sitting height, arm and leg lengths) were studied in the age span of 3 to 18 years. A significant average annual increase of all four anthropometric parameters were observed up to 14 and 15 years of age in girls and 16 years of age in boys, showing that girls had a shorter growing period. In the prepubertal period until 9 years of age, gender differences were negligible. At the age of 10, boys were overgrown by girls in all parameters due to the earlier onset of puberty in girls. The growth gains for girls, when compared with those for boys, show a different pattern across variables. The female growth advantage remained in a two years period for the limbs length, but in a three year period for stature and the longest, for 4 years, for sitting height. The male predominance in size had an onset at the age of 13 for the limbs and in the age of 14 for stature and sitting height. The patterns of sexual dimorphism in stature and sitting height during growing years are similar to those observed in other populations of Europe. Growth of Croatian children and youth is very similar to that of the tallest European populations.     

Body build structure of neonates

The paper presents anthropometric data on 292 healthy neonates delivered of normal births at the Women's Hospital of Tartu University (150 boys and 142 girls). The parameters of the neonates' physical development measured included height, weight, sitting height, length of sternum and abdomen, shoulder width, upper and lower width and depth of thorax, width and depth of abdomen, D. cristarum, D. trochanterica, pelvic depth, 12 circumferences, foot length and two skinfolds (on abdomen and back). The mean weight of a neonate was 3620.5 g±448.7 g (minimum 2400 g and maximum 4854 g). Boys were somewhat heavier than girls (3684.7 g and 3551.3 g respectively). The average height of the infants was 49.9 cm±1.9 cm (minimum 44 cm and maximum 54.5 cm). Correlation analysis of the characteristics showed that body structure is a system of wellcorrelated anthropometric measurements where the leading role belongs to height and weight. The changes in the relation between height and weight (height-weight classification in 3×3SD classes) cause systemic changes in other measurements. Therefore, in further micropaediatric and clinical research, the height-weight classification could be used as the primary model of the body as a whole.     

Parents’ education and child body weight in France: The trajectory of the gradient in the early years

This paper explores the relationship between parental education and offspring body weight in France. Using two large datasets spanning the 1991–2010 period, we examine the existence of inequalities in maternal and paternal education and reported child body weight measures, as well as their evolution across childhood. Our empirical specification is flexible and allows this evolution to be non-monotonic. Significant inequalities are observed for both parents’ education – maternal (respectively paternal) high education is associated with a 7.20 (resp. 7.10) percentage points decrease in the probability that the child is reported to be overweight or obese, on average for children of all ages. The gradient with respect to parents’ education follows an inverted U-shape across childhood, meaning that the association between parental education and child body weight widens from birth to age 8, and narrows afterward. Specifically, maternal high education is correlated with a 5.30 percentage points decrease in the probability that the child is reported to be overweight or obese at age 2, but a 9.62 percentage points decrease at age 8, and a 1.25 percentage point decrease at age 17. The figures for paternal high education are respectively 5.87, 9.11, and 4.52. This pattern seems robust, since it is found in the two datasets, when alternative variables for parental education and reported child body weight are employed, and when controls for potential confounding factors are included. The findings for the trajectory of the income gradient corroborate those of the education gradient. The results may be explained by an equalization in actual body weight across socioeconomic groups during youth, or by changes in reporting styles of height and weight.     

Critical period for menarche derived by the wavelet interpolation method from changes in BMI with age in South Korean girls

Recently, few studies regarding the changes in BMI with age have been reported. In the present study, the wavelet interpolation method (WIM) was applied to the changes in BMI with age from the first grade of elementary school until the second year of high school in Korean girls, and the relationship between age at the maximum peak velocity (MPV) of BMI and age at menarche was confirmed by determining the age at MPV of BMI. Age at menarche and activity status were obtained from questionnaires given to 263 second grade high school girls in the Pusan area of South Korea. Moreover, longitudinal growth data on height and weight from the first grade of elementary school until the second year of high school (from 1997 to 2008) were obtained from health examination records. BMI was calculated from height and weight values from the first grade of elementary school until the second year of high school, and wavelet interpolation was applied to the distances of BMI in each grade. The change curve of BMI with age was determined by wavelet interpolation, and the age at MPV of BMI was determined from the changes in the velocity curve with age as the differentiation curve. Age at MPV of BMI was found to be 12.76 +/- 1.6 years, and age at menarche to be 12.34 +/- 1.1 years. The interval in age at the two times was -0.42 +/- 1.6 years, and a significant difference was seen between age at menarche and age at MPV of BMI. The reason that the age at menarche was a little earlier than the age at MPV of BMI is hypothesized to be abnormal melatonin levels influenced by lack of sleep in Korean school girls. However, it is proposed that the age at MPV of BMI is valid as the critical period for the age at menarche.     

Changes in body size, shape and nutritional status of Middle-Class Bengali boys of Kolkata, India, 1982–2002

Growth changes over time among school-aged boys in Kolkata, India, have been investigated using two surveys: 1982--1983 (n=816) and 1999--2002 (n=1187). The two surveys were implemented according to highly similar protocols which strongly adds to the reliability and accuracy of the results of the study. Age-specific average height, weight and BMI all increased during these two decades (by respectively, 3.2cm, 6.1kg and 2.1kg/m2), while relative sitting height and sitting height-subischial leg length ratio decreased for almost all ages between 7.0 and 16.0 years. Moreover, the prevalence of stunting and thinness declined (stunting from 11.2% to 4.9%, p<0.01, thinness from 50.5% to 22%, p<0.01), while the prevalence of overweight increased (from 4.7% to 17.2%, p<0.01). Through analysis of variance, the relationships between various socio-economic factors and anthropometric traits are analyzed. Factors strongly related with positive changes in anthropometric traits are maternal education and family expenditure.     

Pubertal growth of the short normal girl

OBJECTIVES: To determine the timing, magnitude and duration of the pubertal spurt for short normal and average height girls, to compare these with Tanner's standard and to investigate predictors of pubertal growth. METHODS: The growth of 46 short normal and 55 control girls, identified at school entry, was monitored throughout puberty. Height and weight were measured at 6-month intervals from which body mass index (BMI) was derived. Annual velocities were calculated and used to estimate the age and magnitude of peak height velocity (PHV). Age of menarche was recorded to the nearest month. Parents provided information on the child's medical and social history. RESULTS: The mean age at PHV, the magnitude of PHV and age at menarche were similar for both groups and close to Tanner's 50th centile values. Pre-pubertal BMI predicted age at menarche for short and control girls, accounting for 17% of the variance. There was a tendency for early maturing girls of average stature to have greater PHV. However, this relationship was not observed in short girls, nor did any other variable, genetic or environmental, predict the timing or magnitude of their pubertal spurt. CONCLUSIONS: Delayed puberty in short normal girls is unlikely and their growth during puberty is comparable to girls of average height. The pubertal variables measured remain close to Tanner's original standards for both groups, suggesting the lack of a secular trend towards earlier puberty in girls. The onset of menstruation is influenced by pre-pubertal BMI. However, the clinician should be aware that short normal girls have normal pubertal growth and that no genetic or environmental variable can predict the timing or magnitude of their growth spurt.     

Comparison of the Somatic and Psychosexual Maturation in Menarcheal and Nonmenarcheal Girls

This study reports on the relation between somatic and psychosexual development in 911 urban girls age 8 to 17 years. Subjects were examined by anthropometric and questionnaire methods. We compared the variability of somatic proportions and indexes in two groups of girls at the same age, but with different levels of maturation (menarcheal vs nonmenarcheal). We also assessed their attitudes and knowledge in spheres of sexuality, partners, and matrimonial relationships. We observed that menarcheal girls differed significantly for several anthropometrical values (body weight, sitting height, gluteal circumference, arm circumference) for some age groups, and we recorded significant differences in values of some indexes (Quetelet-Bouchard, Pignet-Vervaek, BMI). The psychosexual development of the girls was assessed by the questionnaire method. The girls were asked to explain various terms. The main aim of our questionnaire was to detect the existence of a relationship between somatic and psychosexual development, whether knowledge of menarcheal girls is more advanced than knowledge of nonmenarcheal girls. Our results show that although there is a significant somatic distinction between menarcheal and nonmenarcheal girls, we are not able to unambiguously state that menarcheal girls are more psychosexually developed.     

Are changes in body dimensions of adult females from Italy (Sardinia and Latium) related to secular trend?

This paper presents secular changes in height, weight, sitting height, relative sitting height, BMI and estimated lower limb length in two samples of Italian adult females from Sardinia (Cagliari) and Latium (Rieti). The samples consist of 579 healthy women from the province of Cagliari and 138 from the town of Rieti, aged 20.0-39.9 years, measured in the period 2003-2006. The women were divided into four 5-year age groups. The anthropometric variables were considered according to different socioeconomic status (SES) in the Cagliari sample, while the Rieti sample was considered as a whole, as the SES was homogeneous. ANOVA results suggest that the secular trend was very slow or had come to a halt in the Rieti sample but continues in the Cagliari sample, as shown by the statistically significant differences for estimated lower limb length (p≤0.02), and relative sitting height (p≤0.05). However, these differences disappear after ANCOVA with sibship size and socioeconomic status controlled for, suggesting that they depend mainly on the composition of the Cagliari sample in terms of SES. Therefore, it can be hypothesised that the secular trend might be very slow or has stopped in the Cagliari subsamples homogeneous for SES.     

Body build classification for ordinary schoolgirls (aged 7-18 years) and volleyball girls (aged 13-16 years)

The article describes two Estonian anthropometric cross-sectional studies of 1549 ordinary schoolgirls (aged 7-18) and 46 girls, who regularly practised volleyball (aged 13-16). Data are presented on 22 basic anthropometric measurements and 6 body composition characteristics (body mass index, mean skinfold, body density, relative mass of fat by Siri, absolute mass and relative mass of subcutaneous adipose tissue). All anthropometric variables were classified into five height-weight SD classes. Schoolgirls were divided into six age groups (7-8, 9-10, 11-12, 13-14, 15-16, 17-18). Volleyballers were observed as one group as their age in SD classes did not differ significantly. The classification consisted of five categories: three height-weight concordant categories: I--small (small height, small weight), II--medium (medium height, medium weight), III large--(big height, big weight) and two height/weight discordant categories: IV--so-called pyknomorphs, V--so-called leptomorphs. To assess the differences between classes the Scheffé-test was used (alpha = 0.05). It proved likewise possible to comparatively systematize length, breadth and depth measurements, circumferences and body composition characteristics in all six age groups (7-18 years) of ordinary schoolgirls and in 13-16-year-old volleyballers as in their case the average age did not differ significantly between the classes.     

性发育对女性最大吸氧量的影响

根据是否发生月经，将１１－１３岁女童分为未来潮组及已来潮组，比较两组身高，体重，瘦体重及最大吸氧量的差。结果表明同龄月经来潮组女童身高，体重，瘦体重，ＶＯ２ｍａｘ绝对值，ＶＯ２ｍａｘ／身高及ＶＯ２ｍａｘ／ＨＲｍａｘ均低于已来潮女童，而ＶＯ２ｍａｘ／体重及ＶＯ２ｍａｘ／瘦体重略高于已来潮组女童，产生这种差异的可能原因。     

Gender differences in fat patterning in children living in Ankara

Body composition is an excellent indicator for assessing obesity and nutritional status of both individuals and populations. Youth obesity has important health and social implications, because a large proportion of adult obesity has its origin in childhood. Numerous studies report that adverse levels of cardiovascular diseases risk factors are associated with adiposity in children. Concerning the Turkish population there is up to now only limited information with regard to adiposity in children. The aim of this study was therefore to determine the anthropometric and body composition characteristics and to investigate sex differences in fat patterning including fat distribution in a group of children living in Ankara. The present study evaluated the body composition of 332 boys and 269 girls aged between 8 and 11 years, attending public schools. It was carried out by a cross-sectional study and was focused on that anthropometric variables, which reflect body fat and fat-free mass. Anthropometric measurements including height, weight, triceps and subscapular skinfolds thickness were carried out on these children. The body mass index (BMI) was also calculated. The measurements were used to estimate the two-compartment model of body composition: fat-free mass (FFM) and body fat (BF) from skinfold equations. The mean fat percentage in boys is highest at 11 years (16.8%) and lowest at 10 years (15.6%). In girls these figures come to 18.2% and 17.1%, respectively. Girls of these age groups have a significantly larger percentage of body fat and skinfold thickness. At this young age there is therefore clear evidence of sexual dimorphism in fat patterning, as girls are showing a greater subcutaneous adiposity, which is mainly contributed by the triceps fat. The body fat (kg) increases in both sexes all over the investigated age groups. The Pearson correlation matrix showed a high significant relation between the anthropometric measurements (p < 0.01). The present study confirms the findings that sexual dimorphism of fat patterning in children is to be seen in the age of 8 - 11 years. It furthermore presents basic data of body composition, which could serve as reference data in other studies on the Turkish population.