共查询到20条相似文献,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
7.
J Davies 《International microbiology》1998,1(4):255-258
Microbiology is finally occupying its true position as the pre-eminent field in life sciences. This is due to advances in molecular techniques that confirm the evolutionary significance of the biology of microbes. It is anticipated that the use of comparative genomics will provide information that will advance the understanding of mechanisms of pathogenesis and the importance of secondary metabolism in social microbiology. More emphasis on studies of microbial diversity will increase its value in both fundamental microbiology and its industrial applications. 相似文献
8.
Workman P 《Molecular bioSystems》2005,1(1):17-26
The first golden era of cancer drug development was initiated in the 1940s and gave rise to the cytotoxic agents that dominate current cancer medicine. The second golden era is now underway in which cancer genomics will direct drug development. 相似文献
9.
Di Berardino MA McKinnell RG Wolf DP 《Differentiation; research in biological diversity》2003,71(7):398-401
May 2002 marked the golden anniversary of the first cloned tadpoles. We celebrate this anniversary, as nuclear transplantation of frog cells into enucleated eggs became the prototype for cloning insects, fish, and mammals. We briefly review the salient results from amphibian cloning. Extension of these studies to mammalian species led to cloning adult cells, important advances in understanding nuclear reprogramming, and the construction of transgenic clones for biomedical applications. In addition, murine cloning clarified two problems unresolved in frog cloning: the unequivocal demonstration that nuclei of fully differentiated cells can direct the formation of fertile adults, and that abnormal expression of genes was responsible for the endoderm and neural syndromes in Rana clones. 相似文献
10.
11.
12.
信息时代生态学本科专业微生物学实验课教学浅析 总被引:1,自引:0,他引:1
结合现代生态学本科专业的特点和学科发展需求,对微生物学实验课教学内容设置、实验课教学方法与效果以及课程考核办法进行了思考和探讨。科学地设置实验内容,优化利用学校多媒体网络技术,积极有效地安排实验课时间,充分调动学生的实验课兴趣,使学生更好地学习和掌握微生物学实验技能,为新世纪生态科学的发展培养优秀人才。 相似文献
13.
14.
15.
With the expanding unification of Europe, the face of European science is changing. For some countries these changes are more pronounced than for others. Here, we survey the present state of science, most notably molecular biology research, in Eastern and South-Eastern European countries. We focus on the strategies these countries are taking in their quest for scientific excellence, discuss some of the acute challenges they face and explore several success stories in the making. 相似文献
16.
Allium inutile Makino in Bot.Mag.Tokyo 12:104.1898.- Nothoscordum inutile(Makino)kitamura in Bot.Mag.Tokyo 59:35.1946. 相似文献
17.
18.
The microbiology of mutability 总被引:2,自引:0,他引:2
Bacteria possessing elevated spontaneous mutation rates are prevalent in certain environments, which is a paradox because most mutations are deleterious. For example, cells with defects in the methyl-directed mismatch repair (MMR) system, termed mutators or hypermutators, are overrepresented in populations of bacterial pathogens, with the mutator trait hypothesized to be advantageous in the changing host enviroments faced during colonization and establishment of chronic infections. Error-prone DNA polymerases, such as polIV and polV, function in translesion DNA synthesis, a DNA damage response that ensures genome integrity with a cost of increased mutation. While the biochemical aspects of these mutability pathways are well understood, the biological impacts have received less attention. Here, an examination of bacterial mutability systems and specifically the ecological and evolutionary context resulting in the selection of these systems is carried out. 相似文献