浙西江山晚奥陶世三分贝族—新属——Costitrimerella

Costitrimerella gen. nov. 属于无铰纲腕足动物中的三分贝族.模式种Costitrimerella costellata gen. et sp. nov. 的模式标本采自浙江江山城西约5km的坛二村北和(土弄)里上奥陶统黄泥岗组的硅质结核中.因发育良好放射状壳线、背肌台前部强烈高隆又缺失台穹构造而与本族其它15属(壳表均光滑仅饰同心生长线纹)有重要的差别,它可能代表奥陶纪晚期三分贝族的一个奇特支系.志留纪三分贝族大都被认为是浅水产物.江山黄泥岗组紫红色泥岩中含深水的叶月贝(Foliomena)腕足动物群,但未寻获三分贝族化石,而夹于泥岩中的硅质结核未见叶月贝动物群的成员,却产三分贝族的代表,其生存环境尚待深入探查.     

浙西江山晚奥陶世三分贝族—新属——Costitrimerella*

Costitrimerella gen. nov. 属于无铰纲腕足动物中的三分贝族.模式种Costitrimerella costellata gen. et sp. nov. 的模式标本采自浙江江山城西约5km的坛二村北和(土弄)里上奥陶统黄泥岗组的硅质结核中.因发育良好放射状壳线、背肌台前部强烈高隆又缺失台穹构造而与本族其它15属(壳表均光滑仅饰同心生长线纹)有重要的差别,它可能代表奥陶纪晚期三分贝族的一个奇特支系.志留纪三分贝族大都被认为是浅水产物.江山黄泥岗组紫红色泥岩中含深水的叶月贝(Foliomena)腕足动物群,但未寻获三分贝族化石,而夹于泥岩中的硅质结核未见叶月贝动物群的成员,却产三分贝族的代表,其生存环境尚待深入探查.     

川东南中奥陶统大沙坝组的腕足动物群

四川东南部长宁双河及其附近地区的中奥陶统上部大沙坝组以特殊的岩相和生物相有别于黔北的可比地层十字铺组和鄂西的牯牛潭组,地层中漂浮相化石(笔石)与底栖壳相化石(如腕足动物和三叶虫)多次交互出现,笔石动物属于上层下垂对笔石动物群(Didymograptus artus Fauna),时代为中奥陶世Darriwilian(相当于Arenig最晚期至Llanvirn)。在所采集的3300余枚化石标本中有近90％是腕足动物化石,经研究共鉴定出19属21种,分属于4目7超科15科,正形贝目和扭月贝目分别有8属,占全部属群的84％。根据属的生物地理分布,该动物群中广布型分子7属、区域性分子6属,仅限于华南的土著性分子占总量的31．6％,显示出此期华南腕足动物群具有较强的地方性色彩,进一步证实中奥陶世海洋生物强分区性的推断。该腕足动物群宜称作Saucrorthis-Glyptorthis动物群。在统计分析的基础上,识别出Saucrorthis-Glyptorthis群落,包括三个以腕足动物占优势的化石群集(association),即Glyptorthis?simplex群集、Saucrorthis obscura群集和Calyptolepta chengkouensis群集,并结合沉积岩石学以及其它共生化石门类进行群落生态分析,认为该群落所生活的环境以正常浅海砂泥质底域为主(相当于BA2-3)。与上扬子台地贵州遵义十字铺组和重庆城口厚坪组两个相近腕足动物群相比,长宁地区中奥陶世的Saucrorthis-Glyptorthis动物群更接近于厚坪组所产者。与世界上其它一些同期且具相似生态位的动物群相比,除与哈萨克斯坦南部的同期动物群比较接近外,与澳大利亚、北美、英国等地的同期动物群几乎毫无联系,指示华南中奥陶世腕足动物群可能代表一个独特的生物地理小区。     

吉中地区晚古生代腕足动物古生物地理与环境的协同演化*

吉中地区发育了普里道利期—洛霍考夫期Retziella、杜内期通气沟组以及空谷期—沃德期哲斯等腕足动物群。前两者属于"暖水"动物群、后者属于"凉水"动物群。同时参考珊瑚和等动物群分析,说明吉中地区从普里道利期至阿瑟尔期发育"暖水"动物群,从空谷期到沃德期发育"凉水"动物群。"凉、暖"转换是以寿山沟组的Monodiexodina动物群为代表,发生在萨克马尔期。"凉、暖"水动物群的发育及其转换是构造古地理与气候变化双重因素导致的结果。晚志留世—早泥盆世,西伯利亚板块、哈萨克斯坦板块、佳-蒙地块均位于中—低纬度带。吉中地区晚志留世—早泥盆世(乃至中泥盆世)腕足动物群属于"暖水"动物群,古生物地理区划属于中-澳生物地理区。石炭纪,东欧板块东北缘、哈萨克斯坦板块大部分地区、佳-蒙地块南缘属于特提斯洋北缘构造域,发育了特提斯洋北缘腕足动物群,形成了特提斯北缘生物地理区,吉中地区腕足动物群属于这一生物地理区。空谷期—沃德期凉水型哲斯腕足动物群的形成是由于佳-蒙地块西端与塔里木板块以及华北板块西端拼合,形成了西拉木伦洋构造域,以及此时期全球降温事件导致的结果。古生物地理、构造古地理以及古气候之间的协同演化关系表明吉中地区晚古生代地层应属于佳-蒙地块南缘的大陆边缘沉积。     

陕西大荔一早更新世哺乳动物群

陕西大荔县洛河下游后河村附近游河组之上黄褐色砂砾层中,发现一个很有意义的动物群.动物群中含有典型的第四纪哺乳动物化石,如似三门马 (Equus cf. sanmeniensis)、平额象 (Archidiskodon planifrons)、奥米加鼢鼠 (Myospalaxomegodon) 和复齿拟鼠兔 (Ochotonoides complicidens) 等.经过对动物群特点、岩相古地理及古气候的分析,并与华北、华南及欧洲同期对比,该动物群在时代上介于狭义泥河湾期与游河期之间,名为后河村期.     

塔里木中央隆起区上奥陶统的牙形刺

塔里木板块中央隆起区的上奥陶统,即巴楚露头剖面吐木休克组和良里塔格组以及塔克拉玛干沙漠腹地塔中油田井下良里塔格组皆为灰岩相.作者对前人报道的牙形刺带作了修改,首次系统描述牙形刺动物群全貌,共计14属21种.在曾归入Pygodus serra带和P.anserinus带的吐木休克组底部和下部发现Yangtzeplacognathus jianyeensis,故应改为Yangtzeplacognathus jianyeensis带;吐木休克组中部因发现Baltoniodus alobatus和B.variabilis共生,应属B.alobatus带.在Yangtzeplacognathus jianyeensis带和Baltoniodus alobatus带之间尚未发现可靠的B.variabilis,因此是否存在B.variabilis带尚存疑问.巴楚露头区上奥陶统的牙形刺序列由下而上应为Yangtzeplacognathus jianyeensis带,Baltoniodus variabilis带?,B.alobatus带和Belodina confluens带.塔中的良里塔格组则可识别出B.confluens带和Yaoxianognathus yaoxianensis带.将中央隆起区牙形刺动物群组合与其相邻的柯坪地块进行对比,说明晚奥陶世因两个地理区水深的差异导致牙形刺带完整性的差异.     

塔里木柯坪羊吉坎剖面柯坪塔格组下段(上奥陶统)遗迹化石及其古环境意义

塔里木板块柯坪山系的柯坪塔格组下段可对比为上奥陶统,属浅海偏快速碎屑岩沉积相带。羊吉坎剖面距柯坪塔格组底界之上约20—30m的中—厚层细砂岩和粉砂岩局部薄层中赋存遗迹化石,本文鉴定为5属9种,包括Cruziana rouaulti Seilacher,1970,Cruzianaichnosp.,Rusophycus biloba Vanuxem,1842,Rusophycus didymus Salter,1856,Rusophycus cf.eutendorfensis Linck,1942,Chondrites ichnosp.,Gordia marina Emmons,1844,Planolites montanus Richter,1937,Thalassinoides horizontalis Myrow,1995。其中Planolites与Chondrites为穿相分子,Cruziana与Rusophycus为Cruziana遗迹相的典型分子,Thalassinoides与Gordia在早古生代也可见于Cruziana遗迹相,因此该段遗迹化石组合可归于Cruziana遗迹相。羊吉坎剖面柯坪塔格组下段极浅海带的浑浊水体环境导致大多数时间段中壳相生物丰度偏低,可推测这些遗迹化石的造主多是分异度低的机会种群,它们在相对很短的时间段栖居活动于海底表面,随机形成遗迹化石密集的薄层。     

新疆西准噶尔地区泥盆-石炭系界线附近的腕足动物(长身贝类、无窗贝类及穿孔贝类)

新疆西准噶尔沙尔布尔提山地区泥盆系—下石炭统发育良好,各门类海相生物化石众多,尤以腕足类化石最为丰富。根据对采自该地区3个剖面(布龙果尔剖面、和布克河剖面、俄姆哈剖面)上腕足类的详细研究,系统描述长身贝类4属4种,无窗贝类2属3种,穿孔贝类2属2种,穿孔贝类(Dielasma cf.D.? utah(Hall and Whitfield),Cranaena cf. hannibalensis Moore)为该地区首次报道。除无窗贝类Cleiothyridina cf. kusbassica Besnossova在俄姆哈剖面可延续进入下石炭统之外,其余属种皆产自上泥盆统。上述腕足动物属于Syringothy-ris-Spirifer动物群的重要分子,时代为晚泥盆世—早石炭世,大致对应于牙形石中praesulcata带至sandbergi带(法门最晚期—早石炭世)。上述腕足动物群在组成上与北美、乌拉尔地区及库兹涅茨盆地的化石组合较为相似。     

新疆塔克拉玛干沙漠轮南区奥陶纪牙形刺及Pygodus属的演化北大核心CSCD

详细描述我国新疆塔克拉玛干沙漠东北部轮南探区50井的中-上奥陶统界线附近的牙形刺动物群,包括Pygodus anserinus,P.serra,P.xinjiangensis,Ansella jemtlandica,Cornuodus longibasis,Periodon aculeatus,Protopanderodus calceatus,P.cooperi,P.varicostatus,Scabbardella altipes,Spinodus spinatus和Cahabagnathus sweeti等,由上而下可划分Pygodus anserinus,P.serra和P.xinjiangensis等3个牙形刺带,并以Pygodus anserinus带的底界稍偏上处视为中-上奥陶统界线。尤为重要的是,本文对Pygodus xinjiangensis的有效性、Pygodus属的演化趋势及其3个种的区别进行详细讨论,同时说明Pygodus anserinus由P.serra演化而来。     

老挝北部宾夕法尼亚纪的一个新(筳)类动物群

作者报道了一个小型■类动物群,包括Eostaffella? sp., Pseudoendothyra sp., Staffella pseudosphae-roidea Dutkevich, Neostaffella ( N.)sp ., Profusulinella bona Grozdilova et Lebedeva以及P.cf .prisca (Depart) ,此动物群是在老挝北部琅勃拉邦省西南部的Thong Phiang Vilay村附近的石灰岩山中发现的。根据Profusulinella bona和P.cf. prisca的出现,该动物群的时代可归到晚石炭世宾夕法尼亚纪巴什基尔期或莫斯科期最早期。这是在老挝北部对该时代■类动物群的首次报道。当前■类动物群证明琅勃拉邦地区和泰国北部的黎地区在地质上有重要的关系,表明老挝北部地区从地质构造上属于印度支那板块的边缘。     

Crystal structure, detonation performance, and thermal stability of a new polynitro cage compound: 2, 4, 6, 8, 10, 12, 13, 14, 15-nonanitro-2, 4, 6, 8, 10, 12, 13, 14, 15-nonaazaheptacyclo [5.5.1.13, 11. 15, 9] pentadecane

A new polynitro cage compound 2, 4, 6, 8, 10, 12, 13, 14, 15-nonanitro-2, 4, 6, 8, 10, 12, 13, 14, 15-nonaazaheptcyclo [5.5.1.1(3,11).1(5,9)] pentadecane (NNNAHP) was designed in the present work. Its molecular structure was optimized at the B3LYP/6-31 G(d,p) level of density functional theory (DFT) and crystal structure was predicted using the Compass and Dreiding force fields and refined by DFT GGA-RPBE method. The obtained crystal structure of NNNAHP belongs to the P-1 space group and the lattice parameters are a = 9.99 ?, b = 10.78 ?, c = 9.99 ?, α = 90.01°, β = 120.01°, γ = 90.00°, and Z = 2, respectively. Based on the optimized crystal structure, the band gap, density of state, thermodynamic properties, infrared spectrum, strain energy, detonation characteristics, and thermal stability were predicted. Calculation results show that NNNAHP has detonation properties close to those of CL-20 and is a high energy density compound with moderate stability.     

Distribution of N,P, K,Ca, Mg,S, Zn,Fe, Mn and Cu in groundnut

Summary Concentration of N, P, K, Ca, Mg and S in summer groundnut crop was higher than in kharif while Zn, Fe, Mn and Cu contents were higher in summer crop. Kernel's N, P and Zn; Leaflet's Ca and Mn; Stem's K and Fe; Root's S and Cu and Petiole's Mg contents were highest. Shell's N, P, K, Mg, S, Zn and Cu; Kernel's Ca, Fe and Mn contents were the least. N, P, K, S, Zn and Cu concentrations decreased linearly as the crop grew. Ca, Mg, Fe and Mn concentrations did not display any distinct pattern. Ca concentration was positively correlated with pod yield in both the seasons.     

Relations of the Al,B, Ba,Br, Ca,Cl, Cu,Fe, K,Li, Mg,Mn, Na,P, S,Si, Sr,and Zn mass fractions to morphometric parameters in pediatric and nonhyperplastic young adult prostate glands

The variation with age of the 18 trace element mass fractions and some histological characteristics of intact prostate glands of 50 subjects aged 0–30 years was investigated by instrumental neutron activation analysis, inductively coupled plasma atomic emission spectrometry, and a quantitative morphometric analysis. Mean values ± standard error of the mean (M ± SΕΜ) for the mass fractions (in milligrams per kilogram wet tissue) of these trace elements in pre-puberty were: Al 28.5 ± 9.0, B 0.40 ± 0.11, Ba 1.48 ± 0.44, Br 10.5 ± 1.5, Ca 241 ± 30, Cl 3,203 ± 278, Cu 3.51 ± 0.89, Fe 33.7 ± 4.1, K 2,364 ± 145, Li 0.020 ± 0.004, Mg 153 ± 23, Mn 0.46 ± 0.06, Na 2,286 ± 130, P 1,391 ± 100, S 1,698 ± 132, Si 62 ± 11, Sr 0.38 ± 0.08, and Zn 27.6 ± 2.3. During puberty and postpuberty, when there is a significant increase in circulating androgens, the mean values were: Al 7.2 ± 1.4, B 0.21 ± 0.05, Ba 0.25 ± 0.06, Br 5.8 ± 1.0, Ca 433 ± 81, Cl 2,314 ± 201, Cu 1.77 ± 0.13, Fe 20.9 ± 1.6, K 2,585 ± 118, Li 0.0088 ± 0.0014, Mg 232 ± 27, Mn 0.34 ± 0.04, Na 1,875 ± 107, P 1,403 ± 98, S 1,673 ± 73, Si 22.2 ± 3.1, Sr 0.22 ± 0.03, and Zn 93.3 ± 8.9. Mean values (M ± SΕΜ) of percent volumes (%) of the stroma, epithelium and lumen in the prostate before puberty were 73.4 ± 2.6, 20.4 ± 1.7, and 4.45 ± 0.94, respectively, versus 46.5 ± 2.5, 38.5 ± 1.9, and 14.9 ± 1.2 during puberty and postpuberty. This work’s results confirm that the Zn mass fraction in prostate tissue is an androgen-dependent parameter. For the first time it has been demonstrated that the glandular lumen is a main pool of Ca, Mg, and Zn accumulation and that the stroma is a main pool of Al, B, Ba, Br, Cl, Cu, Fe, Mn, Na, and Si accumulation in the normal human prostate, for the age range 0–30 years. It was concluded that the Ca, Mg, and Zn binds tightly within the prostatic fluid, because the volume of glandular lumen reflects the volume of prostatic fluid.     

Simultaneous measurement of the trace elements Al, As, B, Be, Cd, Co, Cu, Fe, Li, Mn, Mo, Ni, Rb, Se, Sr, and Zn in human serum and their reference ranges by ICP-MS

The goal of this article was to establish reference ranges of the concentration of trace elements in human serum and to compare these results with those reported by other authors. We describe the sample preparation and measurement conditions that allow the rapid, precise, and accurate determination of Al, As, B, Be, Cd, Co, Cu, Fe, Li, Mn, Mo, Ni, Rb, Se, Sr, and Zn in human serum samples (n=110) by inductively coupled plasma-mass spectrometry (ICP-MS). Accuracy and precision were determined by analyzing three reconstituted reference serum samples by comparison with other methods and by the standard addition procedure. The advantages of the ICP-MS method include short time of analysis of the elements mentioned, low detection limit, high precision, and high accuracy. Disadventages include a high risk of contamination due to the presence of some of the elements of interest in the environment, the relatively delicate sample handling, and the high cost of the equipment.     

Reference values for the concentrations of As,Cd, Co,Cr, Cu,Fe, I,Hg, Mn,Mo, Ni,Pb, Se,and Zn in selected human tissues and body fluids

This report attempts to formulate reference ranges of elemental concentrations for 15 trace elements in selected human tissues and body fluids. A set of samples consisting of whole blood, blood serum, urine, milk, liver, and hair were chosen and considered for 15 elements of biological significance: As, Cd, Co, Cr, Cu, F, Fe, I, Hg, Mn, Mo, Ni, Pb, Se, and Zn. The results represent wholly or partially data received from 40 countries of the global regions of Africa, Asia, Europe, North, South, and Central America, Australia, and New Zealand. This survey, even if qualitative, has been useful in demonstrating certain trends of trace-element scenarios around the world. It is of course recognized that both diet and environment exert a strong influence on the distribution pattern of several elements, such as As, Cd, Mn, Pb, Se, and Zn. A limited comparison of the available information on soil status of different countries reflected some interesting associations for elements, such as Mn and Zn. Importantly, this study revealed that only a few countries were in a position to identify a reasonable amount of data on samples requested for this project. Regretably, for a number of countries, any dependable data for even such essential elements as Cu, Fe, and Zn were not available. In view of the nutritional importance of many elements, the time is ripe for concerted efforts by intergovernmental agencies to initiate investigations or commission task forces/projects to generate reliable reference data for selected global regions, which sadly lack data of any kind at present.     

The Effect of Age and Gender on Al, B, Ba, Ca, Cu, Fe, K, Li, Mg, Mn, Na, P, S, Sr, V, and Zn Contents in Rib Bone of Healthy Humans

The effect of age and gender on major, minor, and trace element contents in the intact rib bone of 80 relatively healthy 15–55-year-old women and men was investigated. Contents or upper limit of contents of 16 chemical elements in the rib bone were determined by inductively coupled plasma atomic emission spectrometry (ICP-AES). Mean values (M?±?SΕΜ) for the mass fraction of Ba, Ca, Cu, Fe, K, Li, Mg, Na, P, S, Sr, and Zn (milligram per kilogram of dry bone) were as follows: 2.54?±?0.16, 171,400?±?4,050, 1.35?±?0.22, 140?±?11, 1,874?±?71, 0.049?±?0.011, 2,139?±?38, 5,378?±?88, 75,140?±?1,660, 1,881?±?51, 291?±?20, and 92.8?±?1.5, respectively. The upper limits of contents of Al, B, Mn, and V were <7.20, <0.65, <0.36, and <0.03, respectively. Statistically significant tendency for the Ca, Mg, and P content to decrease with age was found in the human rib bone, regardless of gender. The mass fraction of Fe in the male rib bone increases with age. It was shown that higher Ca, Mg, Na, P, and Sr mass fractions as well as lower Fe content were typical of female ribs as compared to those in male ribs.     

Potential Compounds for Oral Cancer Treatment: Resveratrol,Nimbolide, Lovastatin,Bortezomib, Vorinostat,Berberine, Pterostilbene,Deguelin, Andrographolide,and Colchicine

Oral cancer is one of the main causes of cancer-related deaths in South-Asian countries. There are very limited treatment options available for oral cancer. Research endeavors focused on discovery and development of novel therapies for oral cancer, is necessary to control the ever rising oral cancer related mortalities. We mined the large pool of compounds from the publicly available compound databases, to identify potential therapeutic compounds for oral cancer. Over 84 million compounds were screened for the possible anti-cancer activity by custom build SVM classifier. The molecular targets of the predicted anti-cancer compounds were mined from reliable sources like experimental bioassays studies associated with the compound, and from protein-compound interaction databases. Therapeutic compounds from DrugBank, and a list of natural anti-cancer compounds derived from literature mining of published studies, were used for building partial least squares regression model. The regression model thus built, was used for the estimation of oral cancer specific weights based on the molecular targets. These weights were used to compute scores for screening the predicted anti-cancer compounds for their potential to treat oral cancer. The list of potential compounds was annotated with corresponding physicochemical properties, cancer specific bioactivity evidences, and literature evidences. In all, 288 compounds with the potential to treat oral cancer were identified in the current study. The majority of the compounds in this list are natural products, which are well-tolerated and have minimal side-effects compared to the synthetic counterparts. Some of the potential therapeutic compounds identified in the current study are resveratrol, nimbolide, lovastatin, bortezomib, vorinostat, berberine, pterostilbene, deguelin, andrographolide, and colchicine.