云南崖摩的化学成分研究

从云南崖摩（Amoora yunnanensis(H.L.Li)C.Y.Wu.）树皮的乙醇提取物中分离得到8个化合物,通过波谱方法鉴定它们分别是：3β,7α,16β-trihydroxy-stigmast-5,22-diene(1)、3β,7α,16β-rtihydroxy-stigmast-5-ene(2)、ergosta-5,24(28)-dien-3β,7α-diol(3)、ergosta-5,24(28)-dien-3β,7β,16β-triol(4)、β-amyrone(5)、β-amyrin(6)、11α,12α-epoxy-14-taraxeren-3-one(7)和6－guaiene-4α,10α-diol(8)。其中1和2为新化合物。     

崖白菜属的一个新异名(英文)

根据对崖白菜的腊叶标本和武汉植物园栽培的崖白菜活体植物的研究,结合崖白菜的野外调查,认为全缘叶崖白菜应作为崖白菜的异名处理。     

望谟崖摩枝叶的化学成分及其抗炎活性研究

为寻找传统药用植物望谟崖摩Amoora ouangliensis中的活性成分,采用色谱分离方法进行化合物分离,并通过波谱数据分析方法鉴定化合物的结构。从望谟崖摩枝叶中分得9个化合物,分别鉴定为cabralealactone(1)、cabraleahydroxylactone(2)、eichlerialactone(3)、金色酰胺醇酯(aurantiamide acetate)(4)、金色酰胺醇(benzenepropanamide)(5)、xylogranatinin(6)、丁香醛(7)、cycloartane-3β,24,25-triol(8)和24(R)-19-cyclolanost-3-one-24,25-diol(9)。在脂多糖诱导的RAW264.7细胞炎症模型中,化合物2~4和9显示出一定的活性。上述化合物均为首次从该植物中分得,化合物2~8为首次从该属植物中分得。     

玫瑰花的化学成分研究(英文)

从玫瑰花中分离了7个化合物,通过波谱法和理化性质分别鉴定为没食子酸(1)、咖啡酸(2)、木犀草素(3)、槲皮素(4)、乔松素-7-O-β-D-葡萄糖苷(5)、槲皮素-4’-O-β-D-葡萄糖苷(6)、刺槐苷(7)。化合物2、3、5、6、7为首次从该植物中分得。     

日本榧树果实的化学成分研究

本文研究了日本榧树果实的化学成分。原植物用甲醇提取后经硅胶柱色谱、制备薄层色谱和制备HPLC色谱进行分离纯化,从日本榧树果实中分离得到了4个化合物,用质谱、红外、紫外、核磁等波谱方法鉴定为18-羟基弥罗松酚（1）、kayadiol（2）、花柏酚（3）和落叶松脂素（4）,化合物1．3、4为首次从该植物果实中分离得到。用MTT法检测了化合物1～3的细胞毒性,在浓度100μmol／L时lisa细胞生存率分别为100．00％、26．30％和59．74％。     

米团花的化学成分研究

从米团花(Leucosceptrum canum Smith)鲜叶中分到三个化学成分,经光谱测定和化学反应已确定它们的化学结构分别为异香紫苏醇(isosclaveol)Ⅰ;柳穿鱼黄素(pectolinarigenin)Ⅱ;β-谷甾醇(β-sitosterol)Ⅲ。其中化合物Ⅰ为新的天然存在的labdane类型二萜化合物。     

距花山姜中的两个新半日烷型二萜双聚体(英文)

从距花山姜(Alpinia calcarata Rosc.)的甲醇提取物中分离得到两个化合物,通过紫外光谱、红外光谱、各种高分辨核磁共振光谱和高分辨质谱,鉴定为两个新的含有环丁烯结构的半日烷型二萜双聚体,命名为距花山姜素(calcaratarin G)和距花山姜素H(calcaratarin H)。这种类型的半日烷型二萜双聚体在植物中比较罕见。     

云南松松塔的化学成分研究

采用正相硅胶、RP-18、MCI、Sephadex LH-20柱色谱和中压液相色谱等方法对云南松松塔乙醇提取物的化学成分进行分离纯化,运用现代波谱技术鉴定了13个化合物,分别为:16-降-15-氧代脱氢松香酸(1)、16-降-7,15-二氧代脱氢松香酸(2)、7α,15-二羟基脱氢松香酸(3)、15-羟基-7-氧代脱氢松香酸甲酯(4)、南洋杉酸(5)、异考布松(6)、交链孢酚(7)、罗汉松脂素(8)、(+)-表松脂素(9)、二氢槲皮素3'-O-葡萄糖甙(10)、赤松素(11)、(Z)-3-羟基-5-甲氧基二苯乙烯(12)、松柏醛(13)。所有化合物均为首次从云南松中分离得到,化合物1、2、6、7、9为首次从松属中分离得到。     

半日花的组织培养及植株再生(简报)

半日花(Helianthemum Songaricum Schrenk)是半日花科半日花属落叶小灌木,分布于新疆、甘肃和内蒙古等荒漠地区海拔1000米至1300米山地。为亚洲中部荒漠特有种和古地中海植物区系孑遗种,是生长了7000万年的远古植物。比具有“活化石”之称的水杉和银杏还要早几千万年。植物学家将它及与之同龄的四合木、沙冬青和革苞菊等十几种植物统称为“古老残遗濒危植物”。故而在研究亚洲中部荒漠,特别是研究我国荒漠植物区系的起源以及与地中海     

The Chemical Constituents of Amoora yunnanensis

Two new sterols, 3β,7α,16β-trihydroxy-stigmast-5,22-diene (1), 3β,7α,16β-trihydroxy-stigmast-5-ene (2), were isolated together with six known compounds, ergosta-5,24(28)-dien-3β,7α-diol (3), ergosta-5,24(28)-dien-3β,7β,16β-triol (4), β-amyrone (5), β-amyrin (6), 11α,12α-epoxy-14-taraxeren-3-one (7), and 6-guaiene-4α,10α-diol (8) from the EtOH extract of the bark of Amoora yunnanensis (H. L. Li) C. Y. Wu. Their structures were deduced on the basis of spectral data.     

Guaiane sesquiterpenes from Amoora rohituka

The petroleum ether extract of the stem bark of Amoora rohituka afforded two novel guaiane-derived sesquiterpenoids, 6beta,7beta-epoxyguai-4-en-3-one (1) and 6beta,7beta-epoxy-4beta,5-dihydroxyguaiane (2). The structures of 1 and 2 were determined by extensive NMR and MS analyses and by comparison of their spectral data with related compounds. The relative stereochemistry of the asymmetric centers in 1 and 2, except at C-5 of 2, were determined by selective 1D-NOESY experiments.     

Cytotoxic triterpenes with diverse skeletons from Amoora tsangii

Two new 29-nor-cycloartane triterpenes, amooratsanols A and B (1, 2) along with nine known compounds including two 29-nor-cycloartane triterpenes (3, 9), two lupane triterpenes (4, 5), two cycloartane triterpenes (6, 10), two dammarane triterpenes (7, 8), as well as one dinorcycloartane triterpene (11) were isolated from the leaves and twigs of Amoora tsangii (Merr.) X. M. Their structures were established by spectroscopic methods (IR, HRESIMS, and NMR). The cytotoxicity of 1–11 was evaluated against the human fibro sarcoma HT1080, esophageal cancer TE, and non-small cell lung cancer A549 cell lines by the CCK8 assay. Cycloartanes (1–3, 6, and 9–11) displayed significant cytotoxic activity with IC₅₀ values ranging from 2.56 to 19.05 μM. Among these triterpenes, mooratsanol A (1) showed the most potent cytotoxic activity, with IC₅₀ values ranging from 2.56 to 5.10 μM.     

粗枝崖摩中一个新的三萜(英文)

Five compounds were isolated from the EtOH extraction of the stem of Amoora dasyclada (How et T.Chen) C.Y.Wu (Meliaceae). On the basis of spectroscopic methods, their structures were elucidated as 24, 25-epoxy-tirucall-7-ene-3, 23-dione (1),24,25,26,27-tetranortirucall-7-ene-3-oxo-23(21)-Iactone (2),taraxerone (3),taraxerol (4)and β-sitosterol (5).Among them, compound 1 was a new triterpenoid, compounds 3-5 were firstly obtained from this plant; compound 2,an tetranortriterpenoid, was firstly isolated from natural sources, and its NMR data were assigned for the first time. Moreover, the △^7-bond and the Me-14 in compound 2 were never changed, which has never been found in other tetranortriterpenoids. And the biosynthetic pathway of tetranortriterpenoid was further discussed.     

粗枝崖摩中一个新的三萜

从粗枝崖摩(Amoora dasyclada (How et T.Chen)C.Y.Wu)中分离到5个化合物.通过波谱方法鉴定为:24,25-epoxy-tirucall-7-ene-3,23-dione(1),24,25,26,27-tetranortirucall-7-ene-3-oxo-23(21)-lactone(2),taraxerone(3),taraxerol(4)andβ-sitosterol(5).其中化合物1为一个新的三萜,3～5为首次从该植物中分离得到.化合物2是首次从天然植物中分离得到的一个四降三萜,对它的碳谱和氢谱数据进行了全归属.此外化合物2在碳7位上的双键和14位上的甲基并未发生变化,以前文献中没有报道过与此类似的四降三萜,据此进一步讨论了四降三萜的生物合成路径.     

中国人参花化学成分研究

目的:对人参(Panax ginseng C.A.Mey.)花蕾的化学成分进行研究。方法:采用多种柱色谱技术进行分离纯化,并通过波谱分析方法鉴定化合物的结构。结果:分离鉴定了9个化合物,分别鉴定为咖啡碱(1)、胡萝卜苷(2)、豆甾醇3-O-葡萄糖苷(3)、α-菠甾醇(4)、7-豆甾烯-3β-醇(5)、人参皂苷Rk3(6)、人参皂苷Re(7)、人参皂苷Rg2(8)、谷甾醇(9)结论:其中化合物1为五加科植物中首次分离得到,化合物3、4、5为人参花中首次分离得到。     

肾茶化学成分的研究

从肾茶中分离得到11个已知化合物,通过NMR及MS数据分析,分别鉴定为：5-羟基-6,7,4’-三甲氧基黄酮（1）,5-羟基-6,7,3’,4＇-四甲氧基黄烷酮（2）,orthosipholF（3）,siphonolB（4）,白桦酯酸（5）,2α-羟基齐墩果酸（6）,2α,3α-二羟基-12-烯-28-齐墩果酸（7）,委陵菜酸（8）,蔷薇酸（9）,熊果酸（10）和胡萝卜甙（11）。其中,花合物2-9为首次从该植物中分离得到。     

A Novel Labdane-Type Trialdehyde from Myoga (Zingiber mioga Roscoe) That Potently Inhibits Human Platelet Aggregation and Human 5-Lipoxygenase

We screened myoga extracts for inhibitors of human platelet aggregation and human 5-lipoxygenase. We identified a novel labdane type of diterpene, together with three known diterpenes (miogadial and galanals A and B) from the flower buds of myoga. Spectroscopic data indicated the structure of the new compound to be 12(E)-labdene-15,16,(8β)17-trial (miogatrial). Miogatrial and miogadial were potent inhibitors of human platelet aggregation and human 5-lipoxygenase (5-LOX). The sesquiterpene, polygodial, also exhibited strong inhibitory activity against human platelet aggregation and 5-LOX. On the other hand, galanals A and B did not have inhibitory activity in either experimental system. It thus appears that a 3-formyl-3-butenal structure was essential for the potent inhibition of human platelet aggregation and human 5-LOX.     

肿柄菊的化学成分

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