Structure and gating mechanism of the α7 nicotinic acetylcholine receptor

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Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor

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De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function

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The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone

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How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor

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Single-Cell Transcriptomes Reveal Diverse Regulatory Strategies for Olfactory Receptor Expression and Axon Targeting

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Cryo-EM structure of the β3-adrenergic receptor reveals the molecular basis of subtype selectivity

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A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis

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Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response

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An ammonium transporter is a non-canonical olfactory receptor for ammonia

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Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons

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Engineered cell entry links receptor biology with single-cell genomics

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Structure-guided optimization of light-activated chimeric G-protein-coupled receptors

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Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow

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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

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Divergent Roles for Macrophage C-type Lectin Receptors,Dectin-1 and Mannose Receptors,in the Intestinal Inflammatory Response

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The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands

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Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation

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Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism

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Structural mechanisms of GABAA receptor autoimmune encephalitis

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