Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964

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The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis

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CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma

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SPT5 stabilization of promoter-proximal RNA polymerase II

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Bipartite binding of the N terminus of Skp2 to cyclin A

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CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent KATP channel closure

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Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response

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Comprehensive Analysis of G1 Cyclin Docking Motif Sequences that Control CDK Regulatory Potency In Vivo

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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

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A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase

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MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase

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Mapping the invisible chromatin transactions of prophase chromosome remodeling

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Regulation of Multiple Fission and Cell-Cycle-Dependent Gene Expression by CDKA1 and the Rb-E2F Pathway in Chlamydomonas

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Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade

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Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape

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Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation

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MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity

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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

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