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Recent evidence has indicated that the lysosome is able to act as a signaling organelle that senses nutrient availability and generates an adaptive response that is important for cellular homeostasis. We recently discovered another example of lysosomal signaling where lysosomal calcium release activates the master autophagy regulator TFEB via the phosphatase calcineurin. 相似文献
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Nisha Singh Pallavi Kansal Zeeshan Ahmad Navin Baid Hariom Kushwaha Neeraj Khatri 《Autophagy》2018,14(6):972-991
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