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An alternative pathway for gene regulation by Myc.   总被引:16,自引:3,他引:13       下载免费PDF全文
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Targeting of Miz-1 is essential for Myc-mediated apoptosis   总被引:3,自引:0,他引:3  
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Signaling by TGFbeta regulates the expression of hundreds of genes. The rapid repression of c-Myc stands out because of its roles in growth control and cancer. Recent work shows that c-Myc repression by TGFbeta is mediated by the nuclear translocation of a novel, preformed complex composed of Smad3, E2F4 or E2F5, and the Rb-related factor p107.  相似文献   

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