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The story of cell fusion: big lessons from little worms 总被引:7,自引:0,他引:7
Shemer G Podbilewicz B 《BioEssays : news and reviews in molecular, cellular and developmental biology》2003,25(7):672-682
The ability of two or more cells to unite to form a new syncytial cell has been utilized in metazoans throughout evolution to form many complex organs, such as muscles, bones and placentae. This requires migration, recognition and adhesion between cells together with fusion of their plasma membranes and rearrangement of their cytoplasmic contents. Until recently, understanding of the mechanisms of cell fusion was restricted to fusion between enveloped viruses and their target cells. The identification of new factors that take part in developmental cell fusion in C. elegans opens the way to understanding how cells fuse and what the functions of this process are. In this review, we describe current knowledge on the mechanisms and putative roles of developmental cell fusion in C. elegans and how cell fusion is regulated, together with other intercellular processes to promote organogenesis. 相似文献
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The parasite fauna of two endemic fish species of the genus Comephorus (Cottoidei: Comephoridae) includes 11 species. Six species were found in Comephorus baicalensis and 9--in C. dybowskii. Two species only are endemic for Baikal: Myxidium perniciosum and Gyrodactylus comephori. Other 9 species are distributed throughout Palaearctic region. Ecology of parasites and their hosts is briefly discussed. 相似文献
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