Split conformation of Chaetomium thermophilum Hsp104 disaggregase

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Frozen in time: analyzing molecular dynamics with time-resolved cryo-EM

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Catalytic cycling of human mitochondrial Lon protease

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A multiscale analysis of early flower development in Arabidopsis provides an integrated view of molecular regulation and growth control

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Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms

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Phosphorylation at Ser65 modulates ubiquitin conformational dynamics

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Emergence and widespread circulation of a recombinant SARS-CoV-2 lineage in North America

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Deciphering the principles of the RNA editing code via large-scale systematic probing

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How do antiporters exchange substrates across the cell membrane? An atomic-level description of the complete exchange cycle in NarK

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Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor

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Characterization of the mechanism of bile salt hydrolase substrate specificity by experimental and computational analyses

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Structure of an inactive conformation of GTP-bound RhoA GTPase

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Characterizing Membrane Association and Periplasmic Transfer of Bacterial Lipoproteins through Molecular Dynamics Simulations

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Structural and dynamic insights into α-synuclein dimer conformations

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A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle

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Molecular insights into the biased signaling mechanism of the μ-opioid receptor

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The guidance and adhesion protein FLRT2 dimerizes in cis via dual small-X3-small transmembrane motifs

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Enhanced neutralization resistance of SARS-CoV-2 Omicron subvariants BQ.1, BQ.1.1, BA.4.6, BF.7, and BA.2.75.2

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Chaperones directly and efficiently disperse stress-triggered biomolecular condensates

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Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment

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