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Preferential Inhibition of Penicillinase Induction by Oxytetracycline and Its Effect on the Penicillin Susceptibility of Staphylococci 总被引:1,自引:0,他引:1 下载免费PDF全文
Thomas M. Michael J. Gabriel Michael Benedict F. Massell 《Journal of bacteriology》1967,93(6):1749-1752
Exposure of penicillinase-producing staphylococci to a combination of penicillin and oxytetracycline resulted in a synergistic inhibitory activity of the antibiotics on the bacteria. Oxytetracycline was employed in concentrations having little or no effect on bacterial growth. It was found that the synergistic antibacterial effect was caused by the preferential inhibition of penicillinase induction by oxytetracycline, rendering the staphylococci more susceptible to penicillin. 相似文献
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Alexander Frank Cleverson C. Matiolli Américo J.C. Viana Timothy J. Hearn Jelena Kusakina Fiona E. Belbin David Wells Newman Aline Yochikawa Dora L. Cano-Ramirez Anupama Chembath Kester Cragg-Barber Michael J. Haydon Carlos T. Hotta Michel Vincentz Alex A.R. Webb Antony N. Dodd 《Current biology : CB》2018,28(16):2597-2606.e6
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《Biochemical and biophysical research communications》1997,233(3):778-780
N-Acetylserotonin (NAS) inhibits the peroxidation of linoleic acid induced by a water-soluble initiator, 2,2′-azobis(2-amidinopropane) (ABAP). Lipid peroxidation was detected by the formation of conjugated dienes, monitored spectrophotometrically at 236 nm. N-Acetylserotonin, at concentrations ranging from 200 nM to 20 μM, reduced the rate of ABAP-initiated lipid peroxidation in a concentration-dependent manner. The results of NAS-inhibited lipid peroxidation are compared to the antioxidant activities of melatonin, vitamin E, and a water-soluble vitamin E analog, Trolox. It is suggested that NAS acts as a physiological antioxidant in retinal photoreceptor cells. 相似文献