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The porcine retinoic acid receptor-γ gene (RARG) has been mapped by restriction fragment length polymorphism analysis to porcine chromosome 5. The placement of RARG distal to the diacylglycerol kinase gene increases the length Of the existing map (PiGMaP) and adds a fifth type-I marker to this sparsely mapped chromosome. This augments the homology of pig chromosome 5 and human chromosome 12 established by previous comparative mapping. 相似文献
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Linkage mapping of the MC3R gene to porcine chromosome 17 总被引:1,自引:0,他引:1
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Claire R. Quilter Sarah C. Blott Alan J. Mileham Nabeel A. Affara Carole A. Sargent Darren K. Griffin 《Mammalian genome》2002,13(10):588-594
A combination of FISH and RH mapping was used to study the evolution of sex chromosome genes in the pig. In total, 19 genes
were identified, including 3 PAR genes (STS, KAL, PRK). The gene order of the porcine X Chromosome (Chr) closely resembled
the human X Chr (PRK/STS/KAL–AMELX–EIF2s3X/ZFX–USP9X–DBX–SMCX), suggesting that the porcine X has undergone very little rearrangement
during evolution. For the porcine Y Chr, two linkage groups of 10 NRY genes were found, and the following order was established:
Ypter–(AMELY–EIF2S3Y/ZFY–USP9Y–DBY/UTY)–(TSPY–SMCY–UBE1Y–SRY)–CEN. This gene order showed greater conservation with the murine
Y than with the human Y Chr. In addition, all porcine Y Chr genes mapped to Yp, which is similar to the mouse and included
EIF2s3Y and UBE1Y, which are not present in humans. Interestingly, complete conservation of X/Y homologous gene order was
found between the pig X and Y Chrs, indicating that the porcine Y Chr has not undergone extensive reorganisation with respect
to the X. This suggests that the order of the X/Y homologous genes of the porcine X and Y Chrs may closely resemble the ancestral
gene order of the eutherian sex chromosomes. 相似文献
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