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Mackman RL Lin KY Boojamra CG Hui H Douglas J Grant D Petrakovsky O Prasad V Ray AS Cihlar T 《Bioorganic & medicinal chemistry letters》2008,18(3):1116-1119
Modified purine analogs of GS-9148 [5-(6-amino-purin-9-yl)-4-fluoro-2,5-dihydro-furan-2-yloxymethyl]-phosphonic acid (2'-Fd4AP) were synthesized and their anti-HIV potency evaluated. The antiviral activity of guanosine analog (2'-Fd4GP) was comparable that of to 2'-Fd4AP in MT-2 cells, but selectivity was reduced. 相似文献
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Insertions in the reverse transcriptase increase both drug resistance and viral fitness in a human immunodeficiency virus type 1 isolate harboring the multi-nucleoside reverse transcriptase inhibitor resistance 69 insertion complex mutation 
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下载免费PDF全文 Quiñones-Mateu ME Tadele M Parera M Mas A Weber J Rangel HR Chakraborty B Clotet B Domingo E Menéndez-Arias L Martínez MA 《Journal of virology》2002,76(20):10546-10552
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Eleftherios Michailidis Andrew D. Huber Emily M. Ryan Yee T. Ong Maxwell D. Leslie Kayla B. Matzek Kamalendra Singh Bruno Marchand Ariel N. Hagedorn Karen A. Kirby Lisa C. Rohan Eiichi N. Kodama Hiroaki Mitsuya Michael A. Parniak Stefan G. Sarafianos 《The Journal of biological chemistry》2014,289(35):24533-24548
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Generation and Characterization of a Defective HIV-1 Virus as an Immunogen for a Therapeutic Vaccine
Carmen álvarez-Fernández Alberto Crespo Guardo Javier García-Pérez Felipe García Julia Blanco Laura Escribà-García Jose Maria Gatell Jose Alcamí Montserrat Plana Sonsoles Sánchez-Palomino 《PloS one》2012,7(11)
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Selmi B Deval J Alvarez K Boretto J Sarfati S Guerreiro C Canard B 《The Journal of biological chemistry》2003,278(42):40464-40472
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