共查询到20条相似文献，搜索用时 15 毫秒
1.
Liu Yang 《Human physiology》2005,31(4):486-487
Book Review
Fundamental Principles of Teaching Physiology at Physical Education Institutes (A Review of Fiziologiya cheloveka. Obshchaya. Sportivnaya. Vozrastnaya) (Human Physiology: General, Sports, and Age-Related) by A.S. Solodkov and E.B. Sologub, Moscow: Terra-Sport, 2002) 相似文献2.
Book Review
Book Review:J.D. Sobel and J.A. Vazquez. ContemporaryDiagnosis and Management of Fungal Infections,Handbooks in Health Care Co., Newtown, Pennsylvania,2003. 256 pp. $20.00. 相似文献3.
Mark Largant 《Journal of the history of biology》2006,39(2):407-424
Book Review
Book Reviews: Keith Thomson, Before Darwin: Reconciling God and Nature (New Haven: Yale University Press, 2005), xiv + 314 pp., illus., $27.00. 相似文献4.
Book Review
Badger Badger. T. J. Roper. HarperCollins Publishers. London. 2010, 388 pp. ISBN 978-0-00-733977-8 相似文献5.
Book Review
Proteasome Inhibitors in Cancer Therapy (J. Adams (ed.), Humana Press, Totowa-New Jersey, 2004, 313 p., $ 155.0) 相似文献6.
Jennifer Duda Mobin Karimi Robert S. Negrin Christopher H. Contag 《Biochemistry. Biokhimii?a》2005,70(9):1070-1070
Book Review
Signal Transduction Protocols (R. C. Dickson and M. D. Mendenhall (eds.), in Methods in Molecular Biology, Vol. 284, J. M. Walker (Series Editor), Humana Press, Totowa-New Jersey, 2004, 327 p., $ 99.50) 相似文献7.
Mark Largant 《Journal of the history of biology》2005,38(3):615-648
Book Review
Book Reviews: Carol Armstrong and Catherine de Zegher, eds., Ocean Flowers: Impressions from Nature (New York: The Drawing Center; Princeton: Princeton University Press, 2004), 336 pp., illus., $49.95. 相似文献8.
Toshiyuki Katagi 《Plant Growth Regulation》1989,8(3):283-284
Book Review
Pesticide formulations: Innovations and developmentsB. Cross and H.B. Scher (Eds.), ACS Symposium Series 371. Washington DC: American Chemical Society, 1988. xi + 288 pages. £54.00. ISBN 0-8412-1483-2 相似文献9.
Harry J. Skornia Robert Steele James R. Taylor Anthony W. Hodgkinson Jerry M. Lewis et al. 《Plant Growth Regulation》1991,10(4):377-378
Book Review
Plant cmolecular biology manualS.B. Galvin, R.A. Schilperoort and D.P.S. Verma (Eds.), Dordrecht, The Netherlands: Kluwer Academic Publishers, 1989. £52.00. ISBN 0-7923-0236-2 相似文献10.
Ai-Hsiang Chou Chia-Chyi Liu Jui-Yuan Chang Renee Jiang Yi-Chin Hsieh Amanda Tsao Chien-Long Wu Ju-Lan Huang Chang-Phone Fung Szu-Min Hsieh Ya-Fang Wang Jen-Ren Wang Mei-Hua Hu Jen-Ron Chiang Ih-Jen Su Pele Choi-Sing Chong 《PloS one》2013,8(11)
Background
Enterovirus 71 (EV71) has caused several epidemics of hand, foot and mouth diseases (HFMD) in Asia. No effective EV71 vaccine is available. A randomized and open-label phase I clinical study registered with ClinicalTrials.gov #NCT01268787, aims to evaluate the safety, reactogenicity and immunogenicity of a formalin-inactivated EV71 vaccine candidate (EV71vac) at 5- and 10-µg doses. In this study we report the cross-neutralizing antibody responses from each volunteer against different subgenotypes of EV71 and CVA16.Methods
Sixty eligible healthy adults were recruited and vaccinated. Blood samples were obtained on day 0, 21 and 42 and tested against B1, B4, B5, C2, C4A, C4B and CVA16 for cross-neutralizing antibody responses.Results
The immunogenicity of both 5- and 10- µg doses were found to be very similar. Approximately 45% of the participants had <8 pre-vaccination neutralization titers (Nt) against the B4 vaccine strain. After the first EV71vac immunization, 95% of vaccinees have >4-fold increase in Nt, but there was no further increase in Nt after the second dose. EV71vac induced very strong cross-neutralizing antibody responses in >85% of volunteers without pre-existing Nt against subgenotype B1, B5 and C4A. EV71vac elicited weak cross-neutralizing antibody responses (∼20% of participants) against a C4B and Coxsackie virus A16. Over 90% of vaccinated volunteers did not develop cross-neutralizing antibody responses (Nt<8) against a C2 strain. EV71vac can boost and significantly enhance the neutralizing antibody responses in volunteers who already had pre-vaccination antibodies against EV71 and/or CVA16.Conclusion
EV71vac is efficient in eliciting cross-neutralizing antibody responses against EV71 subgenotypes B1, B4, B5, and C4A, and provides the rationale for its evaluation in phase II clinical trials.Trial Registration
ClinicalTrials.gov __NCT01268787 相似文献11.
《Plant Growth Regulation》1988,7(4):306-308
Book Review
Hormone action in plant development: A critical appraisalG.V. Hoad, J.R. Lenton, M.B. Jackson and R.K. Atkin (Eds.), London: Butterworths, 1987. 315 pages. £21.00. ISBN 0408 007966 相似文献12.
Daniel F. Austin 《Economic botany》2012,66(3):311-319
Book Reviews
Book Reviews Book Review Editor, Daniel F. Austin 相似文献13.
Campbell O. Webb 《Economic botany》2011,65(4):427-439
Book Reviews
Book Reviews Book Review Editor, Daniel F. Austin 相似文献14.
Book Review
Book Reviews 相似文献15.
Jeffrey Baldock 《Plant Growth Regulation》1990,9(4):356-358
Book Review
Biological interactions in soilC.A. Edwards, B.R. Stinner, D. Stinner and S. Rabatin (Eds.), Amsterdam: Elsevier, 1988. vi+380 pages. US$144.75/Dfl. 275.00. ISBN 0-44-87154-3 相似文献16.
17.
Background
The sympathetic neurotransmitter Norepinephrine (NE) contributes to tumorigenesis and cancer progression. This study aims to investigate the role of NE in modulating the immune phenotype and allowing pancreatic carcinoma (PC) cells to escape the immune response.Methods
Varied concentrations of NE and interferon-gamma (IFN-γ) were administrated to MIA PaCa-2 and BxPC-3 cell lines for 48 hours. Proliferation and invasion were then investigated using an MTT assay and a membrane invasion culture system respectively. MHC-I, B7-1, IDO and B7-H1 expression were measured using real-time quantitative RT-PCR, western blotting and immunocytochemistry. The synergistic and time-dependent effects of NE/IFN-γ were also investigated. Adrenergic antagonists were used to identify the relevant target receptor of NE.Results
The results showed that NE had dose-dependent and time-dependent effects on cell biological processes as well as on the expression of MHC-I, B7-1, IDO and B7-H1. These effects occurred mainly via the β2-adrenergic receptor. Long-term NE treatment was able to antagonize some of the effects of IFN-γ (after 2 weeks of treatment), but NE and IFN-γ had significant synergistic stimulatory effects on IDO and B7-H1 expression. The residual effects on biological activities lasted for 2 weeks, while the immunophenotypic changes decreased at early time points after treatment.Conclusions
NE plays important roles in modulating PC cell biological activities and affecting MHC-I, B7-1, IDO and B7-H1 expression in vitro, mainly via the β2-adrenergic receptor (β2-AR) in a time- and dose-dependent fashion. Only at extended treatment durations could NE affect PC cell progression and immune evasion. 相似文献18.
Eddy Maarel 《Plant Growth Regulation》1991,10(3):279-280
Book Review
Progress in theoretical vegetation scienceG. Grabhett, L. Mucina, M.B. Dale and C.J.F. ter Braak (Eds.), Vol 83. Dordrecht: Kluwer Academic Publishers, 1990, 276 pages, £95.00. ISBN 0-7923-0507-1 相似文献19.
《Experimental & applied acarology》1995,19(10):615-615
Book Review
House Dust Mites, how they affect asthma, eczema and other allergiesDes Whitrow: Elliot Right Way Books, Kingswood, Surrey (UK), 1995. Paperback, 191 pp. £3.99 相似文献20.