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Cloning of rat brain protein kinase C complementary DNA 总被引:12,自引:0,他引:12
Y Ono T Kurokawa K Kawahara O Nishimura R Marumoto K Igarashi Y Sugino U Kikkawa K Ogita Y Nishizuka 《FEBS letters》1986,203(2):111-115
Four peptides derived from rat brain protein kinase C were partially sequenced. Using synthetic oligonucleotides deduced from the amino acid sequences as probes, a clone of complementary DNA (cDNA) was isolated from a cDNA library prepared from the same tissue. The nucleotide sequence of this cDNA clone revealed the primary structure of the carboxyl-terminal region as having 224 amino acids, with significant sequence homology with cyclic AMP-dependent and cyclic GMP-dependent protein kinases. 相似文献
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M R Chevallier 《Molecular and cellular biology》1982,2(8):977-984
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