共查询到20条相似文献,搜索用时 15 毫秒
1.
Kai Truusalu Raik-Hiio Mikelsaar Paul Naaber Tõnis Karki Tiiu Kullisaar Mihkel Zilmer Marika Mikelsaar 《BMC microbiology》2008,8(1):132
Background
The aim of the study was to detect whether in experimental Salmonella enterica Typhimurium infection the probiotic Lactobacillus fermentum ME-3 in combination with fluoroquinolone therapy would eradicate S. Typhimurium, prevent the development of liver and spleen granulomas and improve the indices of oxidative stress in the ileum mucosa. 相似文献2.
Mariela C Carrica Patricio O Craig Víctor A García-Angulo Andes Aguirre Eleonora García-Véscovi Fernando A Goldbaum Silvio L Cravero 《BMC microbiology》2011,11(1):95
Background
Salmonella enterica serovar Typhimurium is an intracellular bacterial pathogen which can colonize a variety of hosts, including human, causing syndromes that vary from gastroenteritis and diarrhea to systemic disease. 相似文献3.
Weiyuan Wu Hui Wang Jian Lu Jinsong Wu Minjun Chen Yingchun Xu Yuemei Lu 《BMC microbiology》2010,10(1):32
Background
Typhoid and paratyphoid fever are endemic in China. The objective of this investigation was to determine the molecular features of nalidixic acid-resistant Salmonella enteric serovar Typhi (S. typhi) and Paratyphi (S. paratyphi) from blood isolates in Shenzhen, China. 相似文献4.
Background
Salmonella enterica serovar Hadar (S. Hadar) is a highly prevalent foodborne pathogen and therefore a major cause of human gastroenteritis worldwide. Outer membrane proteins whose production is often regulated by environmental conditions also play important roles in the adaptability of bacterial pathogens to various environments. 相似文献5.
Kevin Howe Attila Karsi Pierre Germon Robert W Wills Mark L Lawrence Richard H Bailey 《BMC microbiology》2010,10(1):197
Background
Salmonellosis may be a food safety problem when raw food products are mishandled and not fully cooked. In previous work, we developed bioluminescent Salmonella enterica serotypes using a plasmid-based reporting system that can be used for real-time monitoring of the pathogen's growth on food products in short term studies. In this study, we report the use of a Tn7-based transposon system for subcloning of luxCDABE genes into the chromosome of eleven Salmonella enterica serotypes isolated from the broiler production continuum. 相似文献6.
Eva Litrup Mia Torpdahl Burkhard Malorny Stephan Huehn Morten Helms Henrik Christensen Eva M Nielsen 《BMC microbiology》2010,10(1):96
Background
Salmonella enterica subsp. enterica is one of the leading food-borne pathogens in the USA and European countries. Outcome of human Salmonella serotype Typhimurium infections ranges from mild self-limiting diarrhoea to severe diarrhoea that requires hospitalization. Increased knowledge of the mechanisms that are responsible for causing infection and especially the severity of infection is of high interest. 相似文献7.
Background
The pagN gene of Salmonella enterica serovar Typhimurium is a PhoP-regulated gene that is up-regulated during growth within macrophages and in vivo in murine models of infection. The PagN protein displays similarity to the Hek and Tia invasins/adhesins of Escherichia coli. Thus far no function has been ascribed to the PagN protein. 相似文献8.
Anu Raghunathan Jennifer Reed Sookil Shin Bernhard Palsson Simon Daefler 《BMC systems biology》2009,3(1):38
Background
Infections with Salmonella cause significant morbidity and mortality worldwide. Replication of Salmonella typhimurium inside its host cell is a model system for studying the pathogenesis of intracellular bacterial infections. Genome-scale modeling of bacterial metabolic networks provides a powerful tool to identify and analyze pathways required for successful intracellular replication during host-pathogen interaction. 相似文献9.
Background
Salmonella enterica and Campylobacter jejuni are amongst the more prevalent bacterial pathogens that cause foodborne diseases. These microorganisms are common contaminants of poultry and poultry products. This study was aimed to evaluate the antibacterial activity of metallic copper surfaces on these important enteropathogens, and to determine the potential acquisition of copper by food exposed to this metal. 相似文献10.
Background
SpiC encoded within Salmonella pathogeniCity island 2 on the Salmonella enterica serovar Typhimurium chromosome is required for survival within macrophages and systemic infection in mice. Additionally, SpiC contributes to Salmonella-induced activation of the signal transduction pathways in macrophages by affecting the expression of FliC, a component of flagella filaments. Here, we show the contribution of SpiC in flagellum synthesis. 相似文献11.
Seongbeom Cho Thomas S Whittam David J Boxrud Joanne M Bartkus A Mahdi Saeed 《BMC microbiology》2008,8(1):146
Background
Salmonella enterica serotype Enteritidis (S. Enteritidis) is a zoonotic pathogen, which can be found in many sources including animals and the environment. However, little is known about the molecular relatedness among S. Enteritidis isolates from different sources. We have applied multiple-locus variable number tandem repeat analysis (MLVA) to study the genetic diversity of S. Enteritidis isolates from human and non-human sources. 相似文献12.
Valentina Rosu Mark S Chadfield Antonella Santona Jens P Christensen Line E Thomsen Salvatore Rubino John E Olsen 《Acta veterinaria Scandinavica》2007,49(1):14
Background
Salmonella enterica serotype Gallinarum (S. Gallinarum) remains an important pathogen of poultry, especially in developing countries. There is a need to develop effective and safe vaccines. In the current study, the effect of crp deletion was investigated with respect to virulence and biochemical properties and the possible use of a deletion mutant as vaccine candidate was preliminarily tested. 相似文献13.
Jun Sik Lee In Duk Jung Chang-Min Lee Jin Wook Park Sung Hak Chun Soo Kyung Jeong Tae kwun Ha Yong Kyoo Shin Dae Jin Kim Yeong-Min Park 《BMC microbiology》2010,10(1):263
Background
Typhoid, which is caused by Salmonella enterica serovar Typhimurium, remains a major health concern worldwide. Multidrug-resistant strains of Salmonella have emerged which exhibit increased survivability and virulence, thus leading to increased morbidity. However, little is known about the protective immune response against this microorganism. The outer membrane protein (Omp)A of bacteria plays an important role in pathogenesis. 相似文献14.
Background
Salmonellosis is one of the most important bacterial food borne illnesses worldwide. A major source of infection for humans is consumption of chicken or egg products that have been contaminated withSalmonella entericaserotype Typhimurium, however our knowledge regarding colonization and persistence factors in the chicken is small. 相似文献15.
Yang Hong Tongrui Liu Margie D Lee Charles L Hofacre Marie Maier David G White Sherry Ayers Lihua Wang Roy Berghaus John J Maurer 《BMC microbiology》2008,8(1):178
Background
Classical Salmonella serotyping is an expensive and time consuming process that requires implementing a battery of O and H antisera to detect 2,541 different Salmonella enterica serovars. For these reasons, we developed a rapid multiplex polymerase chain reaction (PCR)-based typing scheme to screen for the prevalent S. enterica serovars Enteritidis, Hadar, Heidelberg, and Typhimurium. 相似文献16.
17.
Ashleigh K Andrysiak Adam B Olson Dobryan M Tracz Kathryn Dore Rebecca Irwin Lai-King Ng Matthew W Gilmour Canadian Integrated Program for Antimicrobial Resistance Surveillance Collaborative 《BMC microbiology》2008,8(1):89
Background
Salmonella enterica serovar Heidelberg ranks amongst the most prevalent causes of human salmonellosis in Canada and an increase in resistance to extended spectrum cephalosporins (ESC) has been observed by the Canadian Integrated Program for Antimicrobial Resistance Surveillance. This study examined the genetic relationship between S. Heidelberg isolates from livestock, abattoir, retail meat, and clinical human specimens to determine whether there was a link between the emergence of MDR S. Heidelberg in chicken agri-food sources and the simultaneous increase of MDR S. Heidelberg in human clinical samples. 相似文献18.
Background
Epstein-Barr virus (EBV) infects resting B-lymphocytes and transforms them into immortal proliferating lymphoblastoid cell lines (LCLs) in vitro. The transformed immunoblasts may grow up as immunoblastic lymphomas in immuno-suppressed hosts. 相似文献19.
Background
The survival of Salmonella enterica within the intracellular host niche requires highly co-ordinated expression of virulence effectors predominantly regulated by the SsrAB two-component regulatory system. S. enterica serovar Typhimurium mutants lacking the ssrAB genes are avirulent in mice, highlighting the importance of this regulatory system in vivo. Mutants lacking the gene encoding the alternative sigma factor σE (rpoE) are also highly attenuated for intracellular survival, pointing to a potential connection with the SsrAB regulatory system. 相似文献20.
Matthew R Evans Ryan C Fink Andres Vazquez-Torres Steffen Porwollik Jessica Jones-Carson Michael McClelland Hosni M Hassan 《BMC microbiology》2011,11(1):58