中医经络的光子学研究

在中医经络现代研究的基础上,探讨光子学在经脉循行路线的客观检测,循经感传现象的发生及其实质意义,经络腧穴诊断的客观化以及腧穴双向良性调节作用等研究领域的具体应用.指出中医经络的光子学研究有望借助光子学的学科优势,从科学的角度对我国经络学说进行诠释和量化,为经脉腧穴的光学特性提供重要的实验依据,并有望找到一种非侵人性、无...     

光学神经成像研究进展

大脑功能的成像检测在认知神经科学领域具有极其重要的意义。现代光子学技术的发展为认知脑成像提供了新的研究手段,在神经系统信息处理机制研究中发挥重要作用。文章介绍了在神经元、神经元网络、特定脑皮层功能构筑以及系统与行为等不同层次开展神经系统信息处理机制研究的各种光学成像技术,包括多光子激发荧光显微成像、内源信号光学成像、激光散斑成像和近红外光学成像等,并评述了这些有特色的光学成像技术在多层次获取和分析神经信息中的研究进展。     

免疫光子学——光子学理论与技术在免疫可视化与治疗研究中的应用

正回顾免疫学发展史,每一次研究手段的重大突破与创新都极大地促进了免疫学科的发展.近10多年来,光学分子成像技术飞速发展,以其多色、时空动态、高分辨、跨尺度等优点,为直观可视化描述机体内复杂的细胞与分子事件提供了有效的手段.免疫学的系统化整合性研究已成为发展的大趋势,要真正解决免疫学重大科学问题需要依赖于多学科的密切交叉与合作.在此背景之下,免疫光子学这一交叉学科悄然兴起.免疫光子学主要包括两     

《分子光子学原理及应用》简介

本书绪论回顾了分子光子学的发展历程,并概述了相关的研究领域。第一章根据光学原理、分子学理论、辐射理论和分子场与辐射场的相互作用,介绍了分子光子学的基本原理。第二章总结了光化学反应的特性。第三章讨论了受激发能量转移和光诱导电子跃迁等典型物理化学过程。第四章展示了在电场、磁场或声学场的作用下,光的散射现象和材料诱发变性。第五章介绍了由光辐射引起的光变性,并讨论了非线性光学现象和相干光谱学。     

《分子光子学--原理及应用》简介

本书绪论回顾了分子光子学的发展历程,并概述了相关的研究领域。第一章根据光学原理、分子学理论、辐射理论和分子场与辐射场的相互作用,介绍了分子光子学的基本原理。第二章总结了光化学反应的特性。第三章讨论了受激发能量转移和光诱导电子跃迁等典型物理化学过程。第四章展示了在电场、磁场或声学场的作用下,光的散射现象和材料诱发变性。第五章介绍了由光辐射引起的光变性,并讨论了非线性光学现象和相干光谱学。     

福建师范大学激光研究所简介

福建师范大学激光研究所设在福建师范大学物理系 ,现有专业技术人员 35人 ,其中教授 8人 ,副教授 15人。目前主要研究方向 :生物医学光子学、信息光学、光纤光子学与器件、量子光学、光电子材料、光电子应用技术、激光光谱技术、薄膜光学等。本所现有《光学》、《光学工程》两个硕士点 ,并与浙江大学联合招收《光学工程》专业博士生。生物医学光子学研究方向是本所的主要研究方向 ,已培养了三届《光学工程》专业博士生。本所的《应用光子学》学科是福建省 2 11工程重点学科。福建师范大学激光研究所所长谢树森教授是国家级专家、浙江大学博…     

生物光子学应用

生物光子学是光学技术与生命科学的交叉学科,可以在分子水平上研究细胞的功能和结构,包括生物系统的光子辐射以及这些光子携带的信息,用光子及其技术对生物系统进行检测、加工和改造等。激光扫描共焦显微术、双光子荧光显微术、近场光学扫描显微术和光镊等显微技术在生命科学研究中的应用非常重要。     

多光子发光的稀土上转换纳米颗粒在生物光子学中的研究进展

生物医学光子学的发展,总是伴随并促进着光子学新技术的发展。光学生物成像技术在癌症肿瘤诊断上有着巨大应用,尤其是具有优良发光特性的稀土离子掺杂的上转换发光纳米颗粒与光学生物成像技术的结合进一步发展了生物光子学在这一领域的应用。鉴于近几年很多人对上转换发光纳米粒子的大量研究,本文对其进行了系统的阐述,综述了稀土上转换发光纳米粒子的光学特异性、发光原理及其在光学成像中不可替代的优势;描述了上转换纳米粒子的化学组成,介绍了几种基本的合成方法,重点说明了水热合成法和热分解法,并从材料和光学两方面分析了生物应用的效率优化;总结了目前上转换材料在生物光子学中的几大应用,着重介绍了生物传感、细胞成像、动物成像、漫射光层析成像、光动力治疗、多模式成像六个方面的应用。本文在最后也对今后的研究进行了展望。     

经络传感现象与现代磁疗研究

经络腧穴的历史发展经络学说是中医针灸学的理论基础。据大量古代文献的记述和考古发掘中出土文物的研究,认为针灸术起源于原始社会新石器时代（据今约１００００年至５０００年前,甚至可溯至１０万年前的旧石器时代）。当时只能用砭石（石针）治病,砭石又称针石。用以刺激身体一定部位以消除病痛。所谓“一定部位”,后来称为腧穴。腧穴即为针灸施术部位。腧穴的发现和发展,大至经过了从无定位,无定名到有定位,有定名,再从有定位到有定名发展到有系统分类这一过程。在《内经》以前的古代医籍中,还没有发现腧穴的系统分类,直到《内…     

科学对待中医按摩

中医按摩学是我国古老中医学中的重要学科，与中药、针灸并列为中医的三大形式。其理论基础是经络腧穴学说，经络是人体运行气血、联络脏腑、沟通内外、贯串上下的经路。     

Biomass measurement online: the performance of in situ measurements and software sensors

Biomass measurement is one of the most critical measurements in biotechnological processes. The technologies developed for the measurement of biomass in situ have developed over the years. Because it has been over 10 years since the last review concentrating on practical issues concerning biomass measurements, it is time to evaluate recent developments in the field. This review concentrates on the applications of dielectric spectroscopy, optical density, infrared spectroscopy, and fluorescence for in situ measurement of biomass. The advantages offered by these methods and an economic way of estimating biomass concentration, the software sensors, are considered.     

人体十二经原穴皮肤二氧化碳呼出量相关性的聚类分析

使用高灵敏度二氧化碳（CO_2）测定仪对30例健康人12经原穴的皮肤CO_2呼出量（SRC）进行了测定．对所测24个穴位的SRC进行两两相关计算,使用SAS统计软件对其距离矩阵进行聚类分析．类平均法聚类的结果表明,左右同名穴首先聚类,其次是表里经穴和同名经穴,伪t检验还支持将12经原穴分成两大类．Ward法聚类的结果与类平均法接近．同名穴组、表里经穴组、同名经穴组和非特异组的平均相关系数分别为0.814,0.65,0.514和0.379．秩和检验表明各组之间有显著性差异．本结果为传统中医经络理论中的同经左右相关、表里经相关和同名经相关原理提供了科学支持．     

Preparation and optical parameter characterization of two aldehyde derivative thin films for photonic applications by drop casting method

In this study, thin films of polymer poly(methyl methacrylate) were prepared using a drop casting method. Two newly synthesized aldehyde derivatives, 2‐bromomalonaldehyde and 5,6‐dihydroimidazo[2,1‐b]thiazole‐2‐carbaldehyde, were used at different concentrations to dope the films. The prepared films were transparent and therefore studied for application in photonics. Optical characterization of the samples was carried out using different spectroscopy techniques. Absorption spectra for both samples were obtained using a UV–vis light spectrophotometer. Other significant optical parameters, such as refractive index, extinction coefficient, and band gap energies, were calculated from the absorption spectra. The effect of doping concentration on these parameters was studied. Emission spectra were obtained using a fluorescence spectrophotometer and the effect of doping was observed. Fourier transform infrared spectra of the doped films were obtained and compared with the pure compound to note changes in peak values and peak intensity. This present work studied the effect of doping on optical properties and examined the application of the samples for photonics.     

Extending optical chemical tools and technologies to mice by shifting to the shortwave infrared region

Fluorescence imaging is an indispensable method for studying biological processes non-invasively in cells and transparent organisms. Extension into the shortwave infrared (SWIR, 1000–2000 nm) region of the electromagnetic spectrum has allowed for imaging in mammals with unprecedented depth and resolution for optical imaging. In this review, we summarize recent advances in imaging technologies, dye scaffold modifications, and incorporation of these dyes into probes for SWIR imaging in mice. Finally, we offer an outlook on the future of SWIR detection in the field of chemical biology.     

Microsecond single-molecule tracking (μsSMT)

Here we report on a method to track individual molecules on nanometer length and microsecond timescales using an optical microscope. Our method is based on double-labeling of a molecule with two spectrally distinct fluorophores and illuminating it with laser pulses of different wavelengths that partially overlap temporally. We demonstrate our method by using it to resolve the motion of short DNA oligomers in solution down to a timescale of 100 μs.     

Influence of synthesis parameters on the optical and photocatalytic properties of solvo/hydrothermal CuS and ZnS nanoparticles

Copper sulfide and zinc sulfide nanostructures were synthesized using a solvo/hydrothermal method and a thio Schiff base ligand, N‐benzylidene ethanethioamide, as a source of sulfide ions. The effects of different synthesis parameters including the type of solvent, temperature, and duration of reactions on the morphology of the CuS and ZnS products were investigated using field emission scanning microscopy and transmission electron microscopy, respectively. The structural aspects of the samples were characterized using powder X‐ray diffraction, Fourier transform infrared spectroscopy, and energy dispersive X‐ray analysis. The optical properties of the samples were studied through their optical absorption and photoluminescence spectra. The photocatalytic ability of the as‐synthesized sulfides was explored by studying the colour removal of methylene blue under ultraviolet light irradiation.     

Optical Rotatory Dispersion of Polypeptides in the Near-Infrared Region

For the first time ORD measurements in the near-infrared region from 0.7 to 2.0 μ for well-known polypeptides, namely, poly(γ-benzyl L -glutamate), poly(L -glutamic acid), poly-L -lysine·HCl, poly-S-carbobenzoxymethyl-L -cysteine, and Bombyx mori silk fibroin, were carried out. It was found that the value of the optical activity infrared term, which is proportional to the sum of rotational strengths of vibrational transitions, depends on polypeptide conformation. The optical activity infrared term value is equal to zero for the random-coil conformation, it is small but exceeds the measurement error for the α-helical state, and finally, for the β conformation it is an order of magnitude higher than for the α-helical state. The obtained results permit one to hope that on the basis of ORD measurement in the near-infrared region it will be possible to suggest a method of determining the β-form content in polypeptides and proteins     

基于相关检测的多通道近红外光组织光学测量系统

研制了一套基于相关检测技术的三波长多通道近红外光信号采集系统。采用相敏检波模块CD505R有效提高信噪比。Delphi开发的上位机程序通过串口方式与单片机通信。使用光纤传递光源及探测信号,使系统具有更大的灵活性,适用于多种组织光学特性测量方式。模型实验的结果证明该系统准确可靠,前臂阻断实验表明系统对不同深度组织血氧状况具有较好的测量能力。     

Microsecond Single-Molecule Tracking (μsSMT)

Here we report on a method to track individual molecules on nanometer length and microsecond timescales using an optical microscope. Our method is based on double-labeling of a molecule with two spectrally distinct fluorophores and illuminating it with laser pulses of different wavelengths that partially overlap temporally. We demonstrate our method by using it to resolve the motion of short DNA oligomers in solution down to a timescale of 100 μs.