单细胞技术在干细胞研究中的应用

干细胞是具有自我更新和分化潜能的异质性细胞群体。基于细胞群体水平的干细胞研究不能满足深入认识干细胞生物学本质及实际应用的需要。近年来,单细胞相关技术不断发展和成熟,并正在干细胞基础研究及其相关领域中获得迅速应用。该文以造血干细胞为主要例举,就实验研究中常用的单细胞分离、单细胞克隆分析、单细胞移植、单细胞实时定量PCR及单细胞测序等技术原理及其应用进行综述。     

干细胞生物药物研究进展

胚胎干细胞和成年干细胞经培养能产生更多干细胞也可定向分化成神经细胞、血细胞、肝细胞等特定类型的细胞。其中具有潜能的细胞可用来研究治疗帕金森病、糖尿病和脊髓损伤等疾病的生物药物。     

Notice for Contributors of Cell Research

Aims and ScopesCell Research, a peer-reviewed journal that publishes worldwide new original achievements articles of basic researchin English, plus reviews, features and special report or analyses of current research in Cell and Molecular Biology,aims to the promotion of scientific exchanges between China and all other parts of the world. Our offices in Shanghai,Bethesda, MD, Piscataway, NJ, Toronto, Oxford and London welcome submissions from scientists of all parts in theworld.About the journalCell Research was founded by Shanghai Institute of Cell Biology, Chinese Academy of Sciences in 1990 and sponsoredby Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciencesfrom 2002. It was awarded one of the most important science journals in China Journal Array approved by NationalJournalism Administration of China and supported by the National Natural Science Foundation of China and ChineseAcademy of Sciences. The journal is indexed in Index Medicus,     

胚胎干细胞的研究进展

胚胎干细胞是来源于早期胚胎内细胞团的、具有多向分化潜能的细胞,已经广泛用于生命科学的许多领域,它在医学方面的应用成为医学领域的研究热点.本文对胚胎干细胞在诱导分化、基础研究和临床应用上的研究进展进行了综述,对今后的研究方向进行了展望.     

Web Resources for Stem Cell Research

In this short review, we have presented a brief overview on major web resources relevant to stem cell research. To facilitate more efficient use of these resources, we have provided a preliminary rating based on our own user experience of the overall quality for each resource. We plan to update the information on an annual basis.     

脑细胞增殖研究进展

本文综述了脑细胞增殖发生的主要区域和命运、影响脑细胞增殖的主要因素及脑细胞增殖在干细胞治疗中的应用前景与存在的问题等.     

Notice for Contributors of Cell Research

Cell Research,published bimonthly in English by Institute of Biochemistry and Cell Biology,Shanghai Institutesfor Biological Sciences, Chinese Academy of Sciences, aims at promotion of scientific exchanges between China andall the other parts of the world and reports worldwide new original achievements in cell research.The journalis indexed in Index Medicus,MEDLINE on MEDLARS system,BIOSIS,ISI SCIE~(tm)-available as SciSearch~(tm) on