中医多途径综合疗法治疗宫颈癌术后尿潴留的临床效果评价

目的:评价中医多途径综合疗法治疗宫颈癌术后尿潴留的临床效果和安全性。方法:选择2013年12月至2016年9月我院收治的60例宫颈癌术后出现尿潴留症状的患者,按其意愿将其分为对照组(30例)与研究组(30例),对照组接受水流声诱导、盆底肌锻炼等常规治疗方法,研究组在对照组基础上加以中医多途径综合疗法,比较两组治疗前后中医症状症状积分、自主排尿功能恢复时间、膀胱残余尿量、尿路感染率等情况。结果:治疗前,两组排尿无力、小腹坠胀、倦怠乏力、腰膝酸软积分比较差异均无统计学意义(P0.05);治疗后,两组以上指标均较治疗前明显降低,且研究组小腹胀痛、倦怠乏力积分均明显低于对照组,差异具有统计学意义(P0.05);研究组自主排尿功能恢复时间、膀胱残余尿量均明显低于对照组,差异具有统计学意义(P0.05);研究组尿路感染率为6.78%,明显低于对照组(23.33%),差异具有统计学意义(P0.05)。结论:中医多途径综合疗法治疗宫颈癌术后尿潴留的疗效肯定,可明显缩短病程,并降低尿路感染发生率。     

系统保留盆腔自主神经的广泛子宫切除术治疗宫颈癌及子宫内膜癌的临床效果分析

目的:探讨系统保留盆腔自主神经广泛子宫切除术治疗宫颈癌及子宫内膜癌的临床效果及安全性。方法:收集2013年6月至2014年6月我院收治的宫颈癌和子宫内膜癌患者82例,将其随机分为观察组与对照组,每组各41例。观察组行系统保留盆腔自主神经的广泛子宫切除术,对照组行传统根治性子宫切除术,比较两组的手术时间、术中出血量、术后拔除尿管时间、残余尿量、术后排气以及排便时间以及术中及术后并发症的发生情况。结果:两组的手术时间及术中出血量比较无明显差异(P0.05),但观察组的术后拔管时间、尿残余量、排气及排便时间均较对照组显著缩短或降低(P0.05)。两组的手术并发症主要包括便秘、血便、腹泻、尿路感染、尿失禁、尿频尿急,观察组并发症的总发生率较对照组显著降低(P0.05)。结论:广泛子宫切除术中系统保留盆腔自主神经有利于保护宫颈癌及子宫内膜癌患者的膀胱和直肠功能,降低手术相关并发症,提高患者的术后康复质量与生活质量。     

宫颈癌根治术泌尿系损伤的临床分析

目的：手术是治疗早期宫颈癌的主要手段,本文回顾性分析宫颈癌根治术泌尿系损伤的发生率、探讨防治措施,以减少泌尿系损伤的并发症,提高患者生活质量。方法：对新疆肿瘤医院2003年1月-2008年1月收治的482例早中期子宫颈癌行根治术的患者进行回顾性分析。其中Ia期6例,Ib期131例,IIa期142例,IIb期;鳞癌：440例,腺癌：31例,其他类型：11例。结果：发生泌尿系损伤9例,发生率为1．9％。其中输尿管损伤7例,膀胱损伤2例,其发生率分别为1．5％,0．4％。结论：宫颈癌根治手术致泌尿系损伤是少见但较严重的并发症,对输尿管损伤及时发现及时修补可以避免术后尿瘘的发生,严格操作步骤仍然是子宫颈癌根治术泌尿系损伤防治的关键问题。     

保留盆腔自主神经的宫颈癌根治术对Ib期宫颈癌患者性生活质量及膀胱直肠功能的影响

目的:探讨保留盆腔自主神经的宫颈癌根治术对Ib期宫颈癌患者性生活质量及膀胱直肠功能的影响。方法:选取我院于2010年1月~2017年1月期间收治的90例Ib期宫颈癌患者为研究对象,按乱数表法分为对照组和观察组,每组患者各45例。对照组患者采用传统的宫颈癌根治术治疗,观察组采用保留盆腔自主神经的宫颈癌根治术治疗。比较两组患者的手术情况、性生活质量以及膀胱直肠功能。结果:相比于对照组,观察组患者的手术时间较长,但住院时间较短(P0.05)。观察组术后残余尿量100 m L、50 m L的时间、肛门排气时间、排便时间与对照组比较均明显较短(P0.05)。术后观察组性生活质量各项评分低于对照组(P0.05)。观察组并发症发生率为6.67%,明显低于对照组的22.22%(P0.05)。结论:保留盆腔自主神经的宫颈癌根治术治疗Ib期宫颈癌患者临床疗效显著,有利于患者术后膀胱直肠功能的快速恢复,对患者的性生活质量影响较小,且术后并发症较少。     

网片重建治疗盆腔器官脱垂的临床疗效及安全性评价

目的:探讨经阴道放置网片的全盆底重建术治疗重度子宫脱垂的临床疗效和安全性。方法:选择2010年7月至2015年6月在青岛大学附属医院因重度盆腔器官脱垂接受全盆底重建术的患者126例,回顾性分析患者的临床资料、生活质量评分及并发症等相关资料。结果:126例患者平均手术时间(67.18±18.00)min,出血量(56.27±26.47)m L,留置尿管(3.47±0.94)天,住院天数(4.21±0.93)天。术后尿潴留的发生率为3.96%、阴道壁血肿0.79%、术后肢体疼痛7.14%、下肢静脉血栓0.79%,所有患者术中均无膀胱或直肠损伤等严重并发症的发生。126例患者中,111例完成随访(88.09%,111/126),随访时间为6~48个月,中位随访时间为27个月。术后发生网片暴露1例(0.9%,1/111),网片挛缩1例(0.9%,1/111),慢性盆腔疼痛2例(1.80%,2/111)、新发尿失禁6例(5.4%,6/111)。其中3例为急迫性尿失禁(2.7%,3/111),3例压力性尿失禁(2.7%,3/111)。盆底重建术后共有3例患者出现复发,其中2例因症状明显再次行手术治疗,客观治愈率的为97.29%(108/111),主观治愈率为98.19%(109/111)。与术前相比,术后6个月、12个月生活质量评分(PFDI-20)均较前均明显降低(P0.05)。术后21例患者恢复性生活,性生活疼痛者3例(14.28%),性生活不适者4例(19.04%),总体性生活满意度为85.71%(18/21)。结论:全盆重建术治疗重度盆腔器官脱垂的疗效较好,且网片相关并发症的发生率较低。     

Tumour necrosis factor-alpha (TNFalpha) and interleukin-10 are crucial mediators in post-operative systemic inflammatory response and determine the occurrence of complications after major abdominal surgery

BACKGROUND: The course of serum cytokine levels in patients with postoperative systemic inflammatory response syndrome (SIRS) after major abdominal surgery remains currently unclear. METHODS: Blood was sampled pre- and post-operatively and on days 1 and 2 in 40 patients undergoing major abdominal surgery. Concentrations of tumour necrosis factor-alpha (TNFalpha), interleukin (IL) -6, IL-8, and IL-10 were measured by the LINCOplex assay; those of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) by an enzyme immunoassay. RESULTS: Compared to their pre-operative values, sTREM-1 was elevated on day 2; TNFalpha on day 1; IL-6 and IL-10 post-operatively and on days 1 and 2; and IL-8 post-operatively and on day 1. The duration of operation correlated with TNFalpha and IL-10 at all sampling times, and with IL-6 post-operatively. There were no differences in cytokine concentrations between patients who exhibited post-operative complications and those who did not. IL-10/TNFalpha below 30 was found in all patients with complications (100%) and in 20 patients without complications (64.5%, p: 0.043). CONCLUSIONS: SIRS following major surgery is characterised by complex alterations in cytokine concentrations. The balance between TNFalpha and IL-10 seems to determine the occurrence of post-operative complications.     

腹腔镜下行子宫切除术及淋巴清扫术治疗老年子宫颈癌的疗效

目的:探讨腹腔镜与开腹下行子宫切除术及淋巴清扫术治疗老年子宫颈癌患者的临床疗效。方法:选取2014年1月至2016年1月我院收治的60例老年子宫颈癌患者,随机分为两组,每组30例,A组患者接受开放性子宫切除术及淋巴清扫术,B组患者在腹腔镜下行子宫切除术及淋巴清扫术,比较两组患者的手术情况、术后恢复情况以及术中、术后并发症的发生情况和随访期间的生活质量。结果:B组患者手术中淋巴结的清扫数目明显比A组多(P0.05),术中出血量和术后使用镇痛泵的次数明显少于A组(P0.05),抗生素的使用时间、术后排气时间、膀胱功能恢复时间、引流管滞留时间、住院时间较A组患者明显缩短(P0.05),术中大出血以及术后尿潴留、淋巴囊肿的发生率显著低于A组(P0.05);术后3个月和6个月的I-QOL以及FACT-G评分显著高于A组(P0.05)。结论:腹腔镜下行子宫切除术加盆腔淋巴清扫术治疗老年子宫颈癌患者的临床疗效显著,有利于患者术后恢复,并有效提高患者术后生活质量。     

电针神经刺激疗法联合盆底肌训练对早期宫颈癌广泛性全子宫切除术后患者尿潴留、膀胱功能和免疫功能的影响

摘要 目的：观察电针神经刺激疗法联合盆底肌训练在早期宫颈癌广泛性全子宫切除术后康复中的应用价值。方法：前瞻性收集我院2020年3月~2021年10月期间收治的早期宫颈癌广泛性全子宫切除术患者98例,采用随机数字表法分为研究组和对照组各49例,对照组患者指导其进行盆底肌训练,研究组患者则在盆底肌训练的基础上加以电针神经刺激疗法,对比两组尿潴留发生率以及膀胱功能、免疫功能、盆底功能恢复情况。结果：术后13周时评估结果显示,研究组的盆底肌综合肌力测定正常率高于对照组（P<0.05）。两组术后13周时初始尿意膀胱容量（FVS）、最大尿流率（MFR）、最大尿意膀胱容量（MVS）均较术后1周时升高,残余尿量（PVR）均较术后1周时下降,且研究组术后13周时FVS、MFR、MVS高于对照组,PVR低于对照组（P<0.05）。两组术后13周时血清免疫球蛋白A（IgA）、免疫球蛋白G（IgG）、免疫球蛋白M（IgM）、外周血T淋巴细胞CD3⁺、CD4⁺/CD8⁺均较术后1周时升高,且研究组高于对照组（P<0.05）。研究组尿潴留发生率4.08%（2/49）低于对照组22.45%（11/49）,差异有统计学意义（P<0.05）。结论：电针神经刺激疗法联合盆底肌训练可减少早期宫颈癌广泛性全子宫切除术后患者尿潴留的发生率,改善患者的盆底功能和膀胱功能,促进免疫功能恢复,效果较好。     

Prevention of Urinary Tract Infections After Vaginal Surgery

The technique of care of the bladder and indwelling catheter during the postoperative period was altered to determine whether the incidence of urinary tract infections following vaginal surgery could be reduced. Sixty-nine patients undergoing various types of vaginal reparative surgery were studied. Irrigation of the bladder was carried out with a closed system, four times daily, using chlorhexidine diacetate 1:20,000. Only 12 of the 69 patients showed urinary infection after removal of the catheter, a marked reduction in the usual incidence. It is suggested, therefore, that this technique is helpful in preventing urinary infection after vaginal surgery. It was noted, however, that a further 12 patients who were free of infection at the time of removal of the catheter subsequently developed infection as a result of catherization for residual urine. It is recommended that routine catheterization for residual urine be abandoned.     

三种不同手术方式治疗中老年女性压力性尿失禁疗效及对患者膀胱功能和术后并发症的影响

摘要 目的：探讨耻骨后膀胱尿道悬吊术（Burch）、阴道无张力尿道悬吊术（TVT）及经闭孔经阴道尿道中段悬吊带术（TVT-O）三种不同手术方式治疗中老年女性压力性尿失禁（SUI）疗效及对患者膀胱功能和术后并发症的影响。方法：回顾性分析2019.1-2022.4收治的101例中老年女性SUI患者资料，按手术方式分为Burch组（n=30，Burch术治疗）、TVT组（n=31，TVT术治疗）和TVT-O组（n=40，TVT-O术治疗），观察三组患者临床疗效和手术情况[手术时间、出血量、住院时间、尿管留置时间]，并发症发生率，治疗前后膀胱功能[24h排尿次数、膀胱容量、每次排尿量、残余尿量]及尿道功能指标[尿道长度（FUL）、最大尿道闭合压（MUCP）、Valsalva漏尿点压（VLPP）]变化。结果：Burch组、TVT组、TVT-O组治愈及改善率分别为83.34%、87.10%、87.50%，13.33%、12.90%、12.50%，三组之间比较差异无统计学意义（P>0.05）；TVT组、TVT-O组患者手术时间、出血量、住院时间、尿管留置时间均显著短于Burch组（P<0.05），且TVT-O组患者手术时间显著短于TVT组（P<0.05）；治疗后，三组患者24 h排尿次数、残余尿量均显著降低（P<0.05），膀胱容量、每次排尿量、FUL、MUCP、VLPP水平均显著增加（P<0.05），但三组之间比较差异无统计学意义（P>0.05）；Burch组、TVT组、TVT-O组并发症总发生率分别为20.00%、12.91%、15.00%，三组之间比较差异无统计学意义（P>0.05）。结论：三种术式治疗中老年女性SUI疗效相当，均可有效改善膀胱功能及尿道指标，但TVT与TVT-O术患者康复快，TVT-O手术时间最短，TVT并发症低，可依据患者情况酌情选择。     

Lower urinary tract injuries following blunt trauma: a review of contemporary management

Lower urinary tract trauma, although relatively uncommon in blunt trauma, can lead to significant morbidity when diagnosed late or left untreated; urologists may only encounter a handful of these injuries in their career. This article reviews the literature and reports on the management of these injuries, highlighting the issues facing clinicians in this subspecialty. Also presented is a structured review detailing the mechanisms, classification, diagnosis, management, and complications of blunt trauma to the bladder and urethra. The prognosis for bladder rupture is excellent when treated. Significant intraperitoneal rupture or involvement of the bladder neck mandates surgical repair, whereas smaller extraperitoneal lacerations may be managed with catheterization alone. With the push for management of trauma patients in larger centers, urologists in these hospitals are seeing increasing numbers of lower urinary tract injuries. Prospective analysis may be achieved in these centers to address the current lack of Level 1 evidence.     

低频电刺激联合间歇导尿及Motomed运动训练对脊髓损伤致神经源性膀胱患者膀胱内压力及膀胱容量的影响

目的:探讨低频电刺激联合间歇导尿及Motomed运动训练对脊髓损伤致神经源性膀胱患者膀胱内压力及膀胱容量的影响。方法:选取我院2015年12月～2018年2月收治的脊髓损伤致神经源性膀胱患者92例,根据随机数字表法将其分为对照组(n=46)与研究组(n=46)。两组均给予间歇性导尿、盆底肌训练、膀胱功能训练等常规干预,对照组在此基础上采取低频电刺激,研究组于对照组基础上采取Motomed运动训练,两组均干预2个月。比较两组的临床疗效、治疗前及治疗2个月后的排尿情况(日均单次排尿量、日单次最大排尿量、日均排尿次数)、尿动力学情况(最大尿流率、膀胱容量、残余尿量、膀胱内压力)、LUTS(国际下尿路症状评分)及USDS(泌尿症状困扰评分)。结果:治疗后,研究组总有效率(93.48%)显著高于对照组(78.26%)(P0.05);治疗2个月后,两组日均单次排尿量、日单次最大排尿量、日均排尿次数、最大尿流率、膀胱容量、膀胱内压力均较治疗前显著增多,且研究组以上指标均明显高于对照组(P0.05);两组LUTS及USDS分值均较治疗前显著降低,且研究组以上指标均显著低于对照组(P0.05)。结论:间歇导尿联合低频电刺激与Motomed运动训练可有效改善脊髓损伤致神经源性膀胱患者尿动力学状态及排尿情况,增大膀胱容量及膀胱内压力等,缓解下尿路症状及泌尿症状困扰程度,提高治疗效果。     

Extracorporeal Shock Wave Lithotripsy for Management of Residual Stones after Ureterolithotripsy versus Mini-Percutaneous Nephrolithotomy: A Retrospective Study

Purpose

To compare the efficacy of extracorporeal shock wave lithotripsy in managing residual stones after ureterolithotripsy and mini-percutaneous nephrolithotomy.

Materials and Methods

A retrospective study was carried out of 71 patients with proximal urinary tract stones (greater than 10 mm) who underwent ureterolithotripsy or mini-percutaneous nephrolithotomy at a single institution from 2009 to 2011. The 71 patients were divided into two groups: group I (n = 37) comprised patients who underwent ureterolithotripsy, and group II (n = 34) comprised patients who underwent mini-percutaneous nephrolithotomy. Clinical characteristics, stone-free rates, stone demographics, and complications were evaluated.

Results

The overall stone-free rate was 90.1%. The stone-free rates in groups I and II were 97.3% and 82.4%, respectively. There was a statistically significant difference in the stone-free rates between groups I and II (P = 0.035). Neither serious intraoperative nor postoperative complications were observed. No significant difference in complications was observed between the two groups (P = 0.472).

Conclusions

The results of our study suggest that extracorporeal shock wave lithotripsy is an effective and safe auxiliary procedure for managing residual stones after primary endoscopic surgery. This procedure is associated with a satisfactory stone-free rate and a low complication rate, particularly for residual stones after ureteroscopic procedures.     

Sacral anterior root stimulation for bladder control: clinical results

The Brindley bladder stimulator delivers intermittent stimulation to the anterior sacral roots. The stimulus parameters can be adjusted and set specifically for individuals. Its primary purpose is to improve bladder emptying, thereby to eliminate urinary infection and to preserve kidney function. It also assists in defecation and enables male patients to have a sustained full erection. In our unit so far 38 patients with a complete spinal cord lesion have received a Brindley bladder stimulator implant. One patient died 2 weeks after the surgery due to pulmonary embolism. Two other patients died due to unrelated causes during the follow up period. They used their implants for less than 1 year. Results relating to these 2 patients and the remaining 35 patients who regularly use their implant are presented. The follow-up period ranged from 3 months to 12 years. Residual urine volumes are substantially reduced in all patients; in 24 patients the residual urine volume is less than 30 ml. All patients have increased bladder capacity. Thirty-one patients are continent. Out of 33 males 29 can achieve a sustained full erection using the stimulator. Twenty-seven patients use the implant for bowel function. The following complications were encountered: (1.) Cerebro-spinal fluid collection occurred around the implant in 3 patients during the post-operative period; (2.) Receiver failure occurred in 3 patients. A successful replacement with a new receiver block was carried out in these cases. It is concluded that the use of a bladder stimulator in selected patients gives long term favourable results.     

早期宫颈癌患者围手术期外周血淋巴细胞数与其预后的关系

目的:探讨早期宫颈癌患者围手术期外周血淋巴细胞数与其预后之间的关系。方法:回顾性分析2006年1月至2012年12年就诊于解放军总医院,根据2009年最新宫颈癌FIGO指南诊断为Ⅰb~ⅡA期宫颈癌进行阴式宫颈癌根治术患者的临床病历资料。分析患者的围手术期淋巴细胞数和其无瘤生存期、总生存期间的关系。结果:共143例阴式早期宫颈癌根治术患者纳入研究,随访时间为6~87个月,中位随访时间为53个月。术后,宫颈癌患者外周血淋巴细胞数显著下降。术前外周血淋巴细胞数较高的患者无瘤生存期及总生存期均较外周血淋巴细胞数低于平均水平的患者显著延长(P0.05);术后第三天淋巴细胞数恢复或高于术前水平的患者无瘤生存期较术后第三天淋巴细胞数低于术前水平的患者显著延长(P0.05),但总生存期无明显差异(P0.05)。COX回归分析显示术前淋巴细胞数高于平均水平及术后第三天淋巴细胞数高于或等于术前水平的宫颈癌患者的预后相对较好。结论:术前淋巴细胞数和术后第三天淋巴细胞数的变化均可作为评估宫颈癌术后患者预后的重要参考指标。     

损伤控制性手术在肝胆外科治疗中的临床应用价值

目的:损伤控制性手术(Damage Control Operation,DCO)是针对严重创伤患者进行阶段性修复的外科策略,本文通过观察DCO在肝胆外科治疗中的效果,探讨其临床应用价值,为肝胆外科手术治疗提供参考。方法:选取2012年2月-2013年3月我院收治的90例重症肝胆外伤患者的临床资料进行回顾性分析。将所选病例随机分为对照组和DCO组,每组45例。其中对照组实施常规手术治疗,DCO组实施损伤控制性手术进行治疗。对比两组患者的手术时间,术中出血量、死亡率、术后感染及并发症等。结果:DCO组手术时间为(62.59±8.61)min,术中出血量为(306.48±23.54)m L,死亡率为20%,术后感染率为8.89%,并发症的发生率为11.11%;对照组术时间为(90.35±7.86)min,术中出血量为(600.32±34.21)m L,死亡率为53.33%,术后感染率为24.44%,并发症的发生率为35.56%;DCO组患者的各项指标均优于对照组,差异显著且具有统计学意义(P0.05)。结论:在肝胆外科治疗中采用损伤控制性手术具有明显的临床效果,不但缩短了手术时间,减少出血量,降低死亡率,提高手术成功率,而且降低了术后并发症及感染的发生率,值得推广。     

冠状动脉旁路移植术后血糖变化临床分析

目的:分析冠状动脉旁路移植术(CABG)后患者高血糖的发生率及血糖的变化规律。方法:回顾性分析我院2005年1月～2009年12月行CABG的冠心病患者138例的糖尿病史、术前术后血糖水平、后高血糖和血糖峰值的出现时间等资料。按术前有无糖尿病分为糖尿病组和非糖尿病组,比较析两组的差异。结果:138例患者中有101例发生术后高血糖,发生率为73.2%,非糖尿病组发生率为69.7%;糖尿病组发生率为77.4%,2组术后高血糖发生率未见统计学差异(x2=1.027,P=0.3109)。术前血糖水平与术后高血糖发生率呈正相关,99.0%的患者出现在入住重症强医疗病房(ICU)24h以内,术后血糖峰值的出现时间入住ICU16h,且非糖尿病组出现时间较糖尿病组早。结论:CABG后高血糖的发生率较高,且绝大多数出现在术后24 h以内,术后高血糖发生率与术前血糖水平呈正相关。     

Matched-Case Comparisons in a Single Institution to Determine Critical Points for Inexperienced Surgeons’ Successful Performances of Laparoscopic Radical Hysterectomy versus Abdominal Radical Hysterectomy in Stage IA2-IIA Cervical Cancer

This is a retrospective study which aims to identify major determinants of successful laparoscopic radical hysterectomy (LRH) versus abdominal radical hysterectomy (ARH) performed by inexperienced surgeons for stage IA2-IIA cervical cancer. A total of 161 consecutive patients with stage IA2–IIA cervical cancer who underwent RH were grouped into 2 groups according to the surgeons’ experience with LRH: experienced surgeon versus inexperienced surgeon. After matching for age and risk factors, surgical and survival outcomes were compared. Experienced surgeon selected patients with earlier-stage and fewer risk factors for LRH than ARH, but inexperience surgeons did not. After matching, the vaginal tumor-free margin of LRH was shorter than that of ARH in experienced surgeon group (1.3 versus 1.7 cm, p=0.007); however, the vaginal tumor-free margin was longer than that of ARH in the inexperienced surgeon group (1.8 versus 1.3 cm, p=0.035). The postoperative hospital stay of LRH was shorter than that of ARH in experienced surgeon group (5.5 versus 7.7 days, p<0.001), but not different from that of ARH in the inexperienced surgeon group. Vaginal tumor-free margin >1.8 cm (OR 7.33, 95% CI 1.22–40.42), stage >IB1 (OR 8.83, 95% CI 1.51–51.73), and estimated blood loss >575 mL (OR 33.95, 95% CI 4.87–236.79) were independent risk factors for longer postoperative hospital stay in the inexperienced surgeon group. There was no difference of 5-year-profression-free survival of LRH patients between experienced surgeon and inexperienced surgeon groups after matching (55.1 versus 33.3%, p=0.391). Selection of earlier-stage disease and moderate vaginal tumor-free margin might be important for an inexperienced surgeon to successfully perform LRH with minimal complications in stage IA2–IIA cervical cancer.     

Flap Removal or Flap Preservation During LASEK Surgery

The objective of this study was to evaluate the effectiveness of corneal epithelial flap removal or flap preservation during LASEK operation on myopia and to determine whether there was any accrual of benefit in either approach. From March 2006 to March 2008, some 582 patients (1,164 eyes) who presented with myopia and myopic astigmatism were treated with corrective LASEK operations. They were divided into two groups: one group underwent corneal flap-preservation while the other had the corneal flap removed. Each group comprised 582 eyes, and the data accumulated were retrospectively analyzed. Each patient was examined after 1, 3, 5, and 7 days; 2 weeks; and 1, 2, 3, 6, and 12 months after LASEK surgery to determine their post-operative visual acuity and check for complications. All eyes achieved pre-operative corrected vision 16 weeks after LASEK surgery, with no difference being observed between the two groups. However, there was a significant difference in the ophthalmalgia observed 3 days after LASEK surgery, with the flap-removal group experiencing less post-operative pain than those who had the corneal flap preserved. Furthermore, by 3 days post-operation, the observed corneal epithelial healing was significantly different: again the eyes of those who had the corneal flap removed having a faster recovery than those belonging to the corneal preservation group. In conclusion, the patients who had a flap-removal LASEK operation recorded faster recovery and suffered less ophthalmalgia, but there was no significant difference in the overall outcome in terms of post-operative optimally corrected vision or complications such as haze formation.