Family photographs: A visual heritage 1

In two rural communes of the Vesubie Valley, in the south of France, twenty‐five hundred family photographs were collected. Taken between 1890 and 1950, these pictures not only provided a basic approach to life histories as sensitive aids to photo‐interviews, they represented an understanding of the communities’ past and present and were a powerful source of social life renewal. They also bear witness to the importance of traditions and culture of family photography itself. Crucial confrontations between social classes, ages, sexes, rural and urban cultures, and tradition and modernity are demonstrated by the obligatory staging of photographic rituals     

湿地生态单元定义及其在湿地恢复中的应用

生态单元的概念在生态系统的环境保护和生物保护中被广泛应用。通过阐述湿地生态单元的定义、内涵和外延,分析了湿地生态单元的特征,介绍了湿地生态系统的内部生态单元、湿地"外援"生态单元和人工重建湿地生态单元等在湿地恢复中的应用案例,并对湿地生态单元未来需要关注的研究方向进行了总结,以期为湿地保护与精细化管理提供理论基础和科学依据。     

The burden of rare cancer in Japan: Application of the RARECARE definition

BackgroundDespite the fact that rare cancer is a new target of cancer control in Japan, the incidence of rare cancers is unknown and there is no generally accepted definition of rare cancers in this country. With the aim of calculating incidences of rare cancers in Japan, we therefore adopted a definition and classification of rare cancers that had been published in the European Union (EU) in 2011.MethodsUsing incidence data between 1998 and 2007 submitted by 12 of population based cancer registries in Japan that met our quality criteria and drawing on the EU definition (incidence <6 per 100,000 per year), we estimated the incidences of 845 combinations of tumor sites and histological groups and thus identified the cancers that are rare in Japan.ResultsAfter identifying 193 combinations of tumor sites and histological groups that fit our criteria for rare cancers, we estimated their incidence to be about 75 per 100,000, which corresponds to about 94,800 new diagnoses in 2012 or approximately 15% of all cancer diagnoses. The categorization of rare and common cancers was almost the same in Japan as in EU.ConclusionsThe present study provides an indication of the size of the rare cancer burden in Japan and epidemiological information to explore this. We are expecting further discussion based on our results with stakeholders in order to construct a Japanese definition of rare cancers.     

The architecture of visual cortex and inferential processes in vision

This paper is organised approximately into two halves. In the first half, I review evidence about the structure of the visual system, and I use that evidence to frame what I think are widely held but often implicit ideas about how it works, namely that vision is principally analysis of retinal input. These ideas have been strongly influenced by engineering approaches; form a default view of the visual system that suffuses all the language used to describe it (at least in visual neuroscience); and are to some extent supported by the structural evidence. In the second half, I explore some inconvenient facts from neuroanatomy and neurophysiology which are quite uncomfortable for the traditional view. I then set out a contrary view of how structure and function are linked in the visual system, which is a neurobiological variety of the quite developed view in psychophysics that vision is better understood as knowledge-rich inference. Finally, I explore some of the ramifications of this view for neurophysiological understanding of how the visual system might operate during normal vision.     

Urban and rural river restoration in France: a typology

River restoration (RR) is widely practiced in both rural and urban contexts by combining various goals and measures. The theoretical discourse on RR not yet adequately reflects this breadth of restoration practice. In this study, we investigated 110 French RR projects implemented between 1980 and 2015. We analyzed projects considering eight key design features, main project motivation, restoration goals, project dates, costs, size, funding, river annual discharge, and implemented evaluation procedures. The study (1) provides a detailed account of the French RR effort, (2) compares restoration efforts in urban and rural contexts, and (3) establishes a RR project typology. The results also show that urban RR comprises a wider range of goals and measures than its rural counterpart, includes restoration of riparian habitats, and integrates ecological and social goals. A hierarchical multiple factor analysis yielded five types of projects, Fish RR (14% of the urban and 53% of the rural projects), Blue RR (4%, 7%), Water Framework Directive RR (36%, 40%), Flood protection RR (14%, 0%), and Human RR (32%, 0%). We suggest that the restoration community needs databases that use a project typology as developed in this study. This approach would take into account the multiple facets of RR projects, enabling more transparency into their communication and allow more suitable project comparisons.     

表土在日本植被恢复中的应用

土壤种子库具有区域特有的物种组成和遗传特性,对维持物种多样性和种群密度起到重要作用.表土是具有植被恢复潜在能力的绿化材料.本文在参考大量日本文献的基础上,介绍了利用表土进行植被恢复的特点及分类,从表土混合比例、坡面环境、表土采集深度等3个方面归纳分析了利用表土进行植被恢复的方式,介绍了其在森林、道路、湿地、废弃地等不同类型生境中的应用.最后针对表土在植被恢复应用中存在的问题提出了今后的研究课题:应加强表土在植被恢复中的应用研究,明确绿化技术、恢复目标及表土作为绿化材料的适用性调查方法和标准,开发低成本、高效率的新型表土利用方法.     

The bionic retina: a small molecule with big potential for visual restoration

In this issue of Neuron, Polosukhina et?al. (2012) intravitreally deliver the light-activatable molecule acrylamide-azobenzene-quaternary ammonium (AAQ) to the eyes of mice with end-stage retinal degeneration. Results show that, with the appropriate illumination, AAQ restores light sensitivity and visual behavior.     

Photochemical restoration of visual responses in blind mice

Retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are degenerative blinding diseases caused by the death of rods and cones, leaving the remainder of the visual system intact but largely unable to respond to light. Here, we show that AAQ, a synthetic small molecule photoswitch, can restore light sensitivity to the retina and behavioral responses in?vivo in mouse models of RP, without exogenous gene delivery. Brief application of AAQ bestows prolonged light sensitivity on multiple types of retinal neurons, resulting in synaptically amplified responses and center-surround antagonism in arrays of retinal ganglion cells (RGCs). Intraocular injection of AAQ restores the pupillary light reflex and locomotory light avoidance behavior in mice lacking retinal photoreceptors, indicating reconstitution of light signaling to brain circuits. AAQ and related photoswitch molecules present a potential drug strategy for restoring retinal function in degenerative blinding diseases.     

Molego-based definition of the architecture and specificity of metal-binding sites

Decomposing proteins into "molegos," building blocks that are conserved in sequence and 3D-structure, can identify functional elements. To demonstrate the specificity of the decomposition method, the PCPMer program suite was used to numerically define physical chemical property motifs corresponding to the molegos that make up the metal-containing active sites of three distinct enzyme families, from the dimetallic phosphatases, DNase 1 related nucleases/phosphatases, and dioxygenases. All three superfamilies bind metal ions in a beta-strand core region but differ in the number and type of ions needed for activity. The motifs were then used to automatically identify proteins in the ASTRAL40 database that contained similar motifs. The proteins with the highest PCPMer score in the database were primarily metal-binding enzymes that were related in function to those in the alignment used to generate the PCPMer motif lists. The proteins that contained motifs similar to the dioxygenases differed from those found with PCP-motifs for phosphatases and nucleases. Relatively few metal-binding enzymes were detected when the search was done with PCP-motifs defined for interleukin-1 related proteins, which have a beta-strand core but do not bind metal ions. While the box architecture was constant in each superfamily, the specificity for the metal ion preferred for enzymatic activity is determined by the pattern of carbonyl, hydroxyl or imadazole groups in key positions in the molegos. These results have implications for the design of metal-binding enzymes, and illustrate the ability of the PCPMer approach to distinguish, at the sequence level, structural and functional elements.     

生态环境恢复重建与农村妇女受教育程度的关联性分析

搞清影响农村生态环境的因素,可以为防止农村生态环境的进一步恶化,为农村生态环境恢复和重建奠定基础。调查结果表明农村妇女受教育程度与农村生态环境的恢复与重建呈正相关,并且农村生态环境恶化与农业生产有明显联系;农村妇女受教育程度和农业生产是影响农村生态环境恢复与重建的直接原因。搞好农村生态环境保护与建设必须以发展农村经济为前提,以提高农村的教育投资和农村妇女受教育程度为基础,落实具体的科技措施,重视农业生产引导与管理。     

生态系统修复国内外研究进展与展望

气候变化和人类活动的增加不仅导致生态系统退化、生物多样性丧失、生物圈资源供给能力降低, 而且极大地制约了社会经济的可持续发展。尽管在全世界范围内已实施了大量的保护工作, 但全球生态系统退化仍在继续, 逐渐成为备受关注的全球性问题。文章首先厘清生态系统修复的发展历程、相关概念与理论。其次, 归纳生态系统修复的全球议题, 涉及生态系统服务及其价值评估、生物多样性保护、应对气候变化与碳储存、自然保护地、监测体系与适应性管理、公平性与多主体参与等方面。然后, 总结我国森林、草原、河流与湿地、海洋与海岸带的生态系统退化问题与修复进展, 梳理生态保护红线、自然保护地生态系统修复和国土空间生态保护修复3种措施的进展与不足。最后, 对山水林田湖草沙一体化保护与系统治理、生态系统修复的多元融资政策与渠道、荒野生态保护修复的探索与实践、城镇生态系统修复的研究与应用以及生态系统修复对生物多样性的保护与维持等五个方面进行展望, 以期为我国进一步开展生态系统保护修复的相关研究与实践提供指导。     

Combined definition of seed transfer guidelines for ecological restoration in the French Pyrenees

Question: Can genetic tools combined with phytogeography help to define local plants and how geographically close the source population should be to the restoration site? Location: Subalpine and alpine French Pyrenees. Methods: The main phytogeographic boundaries in the French Pyrenees described by different authors were studied and this geographic pattern was compared with the results of genetic analysis for the four Pyrenean plants studied (Trifolium alpinum, Festuca eskia, Festuca gautieri and Rumex scutatus), based on random amplified polymorphic DNA (RAPD) marker analysis, unweighted pair‐group method with arithmetic averages (UPGMA) analysis and Mantel correlograms comparing geographic and genetic distances. Results: The genetic analysis allowed definition of two main evolutionarily significant units (ESUs) for the plants under study. Although the limit between the two zones was slightly variable according to the species considered, an eastern and a western ESU was consistently observed. This delineation was concordant with the main phytogeographic boundaries of the French Pyrenees. Conclusion: RAPD markers and associated Mantel correlograms can be useful to draw ESUs for individual species when the sampling intensity is relatively dense, and similarities were revealed between species sharing the same distribution range. This delineation allowed integration of infraspecific plant variation in the management of natural resources for revegetation in the Pyrenees. Nevertheless, caution is needed for the establishment of seed pools in order to maximize genetic diversity in each of the pools during collection and production.     

Prevalence of anti-Toxoplasma gondii antibody in domestic horses in Japan

The present study is the first report that investigated the seroprevalence of Toxoplasma gondii infection in domestic horses in various prefectures of Japan and analyzed risk factors for seropositivity. We performed a latex agglutination test for riding/racing horses from 11 prefectures in Japan (783 samples) and 4 groups of Japanese native horses (254 samples). The total seroprevalence of anti-T. gondii antibody in horses examined in this study was 4.24% (44/1037). As for riding/racing horses, we did not find a statistically different T. gondii seroprevalence between sampling prefectures. In contrast, seroprevalence of T. gondii in older horses (> 21 years) was significantly higher than that in younger horses (< 5 years and 11–15 years). There was no significant difference in T. gondii seroprevalence between riding/racing horses and Japanese native horses. Logistical regression analysis revealed that age, but not sex and usage, is a significant risk factor of T. gondii infection for domestic horses in Japan. These findings suggest that domesticated horses in Japan can be horizontally infected with T. gondii by ingestion of food or water contaminated with oocysts.     

Ecological restoration of rural landscapes: stewardship,governance, and fairness

Much rural environmental policy reflects a largely unquestioned belief that if farmers' stewardship ethos could be improved, unsustainable land use would largely be resolved. This article suggests that though a high level of farmer commitment to sustainable land use is necessary for effective stewardship, this is far from sufficient to achieve the desired ends. This article highlights institutional challenges that are not being adequately addressed and poses unanswered questions for public policy and research. These arise from issues that include land tenure norms and rules; governance complexity and fragmentation causing transaction costs and frustration; and problems of fairness related partly to the economic incapacity of some landholders to do what is needed for sustainable land use. This article suggests rural natural resource governance should consider more carefully the accountability of government and the socioeconomic issues of rural sustainability.