New germacranolides from Dicoma anomala

The aerial parts of D. anomala contain, besides known compounds, two new 7,8-germacranolides. The structures have been elucidated by spectroscopic methods. D. argyrophylla lacks lactones.     

New germacranolides from Inula heterolepis

The aerial parts of Inula heterolepis afforded two new germacranolides and a new eudesmanolide, all closely related to haageanolide, which was also isolated.     

Three germacranolides and other constituents from Eremanthus species

The re-investigation of Eremanthus glomerulatus afforded three new germacranolides and a guaianolide, while from E. mollis two known furanoheliangolides and a new phenylpropanol derivative were isolated. The germacranolides most probably are precursors of the widespread glaucolides. The structures were elucidated by spectroscopic methods. The chemotaxonomic situation is discussed briefly.     

Modified eudesmanolides and other sesquiterpene lactones from Wunderlichia mirabilis and Actinoseris polymorpha

Re-investigation of Wunderlichia mirabilis afforded three new modified eudesmanolides of the same type isolated previously from an Onoseris species, and minute amounts of a germacranolide for which a structure only could be proposed. Actinoseris polymorpha also contained a new germacranolide, the angetate of desacetyllaurenobiolide. Structures were elucidated by spectroscopic methods and by some chemical transformations. The significance of these findings is discussed briefly.     

Glaucolide-like sesquiterpene lactones from Cotula cinerea

The aerial parts of Cotula cinerea gave, in addition to widespread compounds, a characteristic diacetylenic spiroketal enolether and several sesquiterpene lactones, three of them being glaucolide-like lactones. The structures were elucidated by highfield ¹H NMR spectroscopy.     

Five germacranolides from Gochnatia discoidea

The investigation of two further Gochnatia species afforded five new germacranolides, all being 8,12-lactones. The structures were elucidated by intensive ¹H NMR studies and by some chemical transformations. The chemotaxonomic aspects are discussed briefly.     

Germacranolides from Dicoma tomentosa

An investigation of the aerial parts of Dicoma tomentosa afforded four new germacranolides and four melampolides together with urospermal A and its 11β,13-dihydroderivative. The structures were elucidated by spectroscopic methods. The chemotaxonomic situation is discussed briefly.     

New germacranolides and other constituents from Trichogoniopsis morii

Trichogoniopsis morii afforded, in addition to known compounds, a new toxol derivative, two diterpenes, a labdane and an ent-kaurane derivative, an eudesmanolide and five germacranolides, a furanoheliangolide and four 1-oxo-germacranolides. The structures were elucidated by spectroscopic methods and a few chemical transformations. The chemotaxonomy of the genus Trichogoniopsis is discussed briefly.     

Seven sesquiterpene lactones from Ferreyanthus species

The investigation of two Ferreyanthus species afforded seven germacranolides which have not been isolated previously. Two derivatives of linalol were also present. The structures were elucidated by spectroscopic methods. Chemotaxonomic relationships are briefly discussed.     

Two sesquiterpene lactones from artemisia species

Two new sesquiterpene lactones, himeyoshin and montanone, were isolated from Artemisia feddei and A. montana, respectively and identified by chemical and spectral data as1α,2α-epoxy-3-oxo-5,6-dihydroalantolactone and 1,10-dihydro-11,13-dehydromatricarin.     

Further ineupatorolide-like germacranolides from Inula cuspidata

The aerial parts of Inula cuspidata afforded in addition to known compounds five germacranolides closely related to ineupatorolide A. Furthermore,     

Ineupatorolide-like sesquiterpene lactones from Dittrichia viscosa

Dittrichia viscosa afforded, in addition to known compounds, minute amounts of nine sesquiterpene lactones, all closely related to ineupatorolide B     

Melampolides and other germacranolides from Blainvillea dichotoma

The aerial parts of Blainvillea dichotoma afforded, in addition to known compounds, seven new sesquiterpene lactones, four related to elephantin, two melampolides and a further cis,cis-germacranolide. The chemotaxonomic situation is discussed briefly.     

Allenic germacranolides,bourbonene derived lactones and other constituents from Vernonia species

An investigation of seven Vernonia species, mainly from northern Brazil, afforded in addition to known compounds three new unusual sesquiterpene lactones with an allenic group. Intensive NMR studies fully established the structures. Furthermore, two lactones derived from bourbonene, two new glaucolides, a new furansesquiterpene, a nerolidol derivative and two other sesquiterpenes derived from eudesmane were isolated. The biogenetic relationships of the sesquiterpene lactones present in Veronia species as well as the chemotaxonomic aspects are discussed.     

A dimeric germacranolide and other sesquiterpene lactones from Mikania species

The investigation of two Mikania species, both previously placed in the genus Kanimia, afforded in addition to known compounds several new germ     

New sesquiterpene lactones and other constituents from Fitchia speciosa

The investigation of Fitchia speciosa afforded, in addition to known compounds, three new sesquiterpene lactones, iso-β-costal, two p-hydroxyacetophenone derivatives and an isoeugenol derivative. The structures were elucidated by spectroscopic methods. The chemotaxonomic situation in this complicated genus is discussed.     

New germacranolides from Liatris species

Three closely related cis-Δ⁴-diepoxygermacranolides were isolated from two Liatris species. Structures of eleganin from L. elegans (Walt.) Michx, and liscundin and liscunditrin from L. secunda (Ell.) Small. were established by NMR spectrometry, chemical transformations and correlation with punctaliatrin previously isolated from L. punctata Hook. Reinvestigation of the latter species yielded another germacranolide liatripunctin whose structure is reported.     

Additional germacranolides from Eupatorium serotinum

The aerial parts of Eupatorium serotinum afforded in addition to compounds reported previously three new germacranolides.     

Further sesquiterpene lactones from Calea and Viguiera species

The aerial parts of Calea clematidea gave three new germacranolides, those of Viguiera procumbens two orizabin derivatives and those of V. linearis dihydrobudlein A. In addition to these lactones, several known ones were isolated.     

New types of sesquiterpene lactones and other constituents from Trichogonia species

The investigation of five Trichogonia species afforded seven new furanoheliangolides, three dilactones of a new type, four pairs of epimeric rearra