共查询到20条相似文献,搜索用时 15 毫秒
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Retinoids as regulators of gene transcription 总被引:2,自引:0,他引:2
Mehta K 《Journal of biological regulators and homeostatic agents》2003,17(1):1-12
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Nucleosomes: regulators of transcription 总被引:41,自引:0,他引:41
M Grunstein 《Trends in genetics : TIG》1990,6(12):395-400
Histones and nucleosomes are involved in the folding of DNA in the eukaryotic cell. Recent evidence suggests that they are also involved in a multistep process of DNA unfolding and gene regulation. 相似文献
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Arabidopsis HsfA1 transcription factors function as the main positive regulators in heat shock-responsive gene expression 总被引:1,自引:0,他引:1
Yoshida T Ohama N Nakajima J Kidokoro S Mizoi J Nakashima K Maruyama K Kim JM Seki M Todaka D Osakabe Y Sakuma Y Schöffl F Shinozaki K Yamaguchi-Shinozaki K 《Molecular genetics and genomics : MGG》2011,286(5-6):321-332
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Global transcription regulators of eukaryotes 总被引:15,自引:0,他引:15
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Archaeal transcription and its regulators 总被引:10,自引:0,他引:10
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SREBP transcription factors: master regulators of lipid homeostasis 总被引:41,自引:0,他引:41
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Global gene expression during the human organogenesis: from transcription profiles to function predictions 总被引:1,自引:0,他引:1
Human embryogenesis includes an integrated set of complex yet coordinated development of different organs and tissues, which is regulated by the spatiotemporal expression of many genes. Deciphering the gene regulation profile is essential for understanding the molecular basis of human embryo development. While molecular and genetic studies in mouse have served as a valuable tool to understand mammalian development, significant differences exists in human and mouse development at morphological and genomic levels. Thus it is important to carry out research directly on human embryonic development. Here we will review some recent studies on gene regulation during human embryogenesis with particular focus on the period of organogenesis, which had not been well studied previously. We will highlight a gene expression database of human embryos from the 4(th) to the 9(th) week. The analysis of gene regulation during this period reveals that genes functioning in a given developmental process tend to be coordinately regulated during human embryogenesis. This feature allows us to use this database to identify new genes important for a particular developmental process/pathway and deduce the potential function of a novel gene during organogenesis. Such a gene expression atlas should serve as an important resource for molecular study of human development and pathogenesis. 相似文献
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