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1.
An epizootic of toxoplasmosis occurred among 22 adult and 30 kit black-footed ferrets (Mustela nigripes) maintained under quarantine conditions at the Louisville Zoological Garden (Louisville, Kentucky, USA) in June, 1992. Black-footed ferrets appear to be highly susceptible to acute and chronic toxoplasmosis. Clinical signs were observed in 19 adults and six kits and included anorexia, lethargy, corneal edema, and ataxia. Two adults and six kits died with acute disease. High antibody titers to Toxoplasma gondii were detected by latex agglutination and modified agglutination assay in 10 black-footed ferrets. One adult and six kits that died with acute clinical signs were necropsied and T. gondii-like organisms were found microscopically in multiple organs. Diagnosis of toxoplasmosis was confirmed by immunohistochemical staining with anti-T. gondii antibodies and by ultrastructural examination. Although the source of T. gondii for black-footed ferrets was not identified, frozen uncooked rabbit was the most likely source. Chronic toxoplasmosis resulted in the death of at additional 13 black-footed ferrets that were adults during the epizootic. Affected animals developed chronic progressive posterior weakness and posterior ataxia 6-69 mo after the epizootic began. Meningoencephalitis or meningoencephalomyelitis associated with chronic toxoplasmosis were identified at necropsy in all 13 ferrets. Precautions to prevent introduction of pathogens into the colony were insufficient to exclude T. gondii. Although toxoplasmosis may cause significant mortality in mustelids, the high mortality of black-footed ferrets in this epizootic was of concern due to their endangered status. This is the first detailed report of toxoplasmosis in black-footed ferrets. 相似文献
2.
Naturally occurring infections with Toxoplasma have been sought in several species of wild birds, and one case has been found in a locally caught pigeon—the first known demonstration of toxoplasmosis of the mammalian type in birds in eastern North America. Experimental infections with a strain of Toxoplasma of human origin have been studied in pigeons, song sparrows, grackles, and chickens. Some of the birds became acutely ill and died within a few days or a week; others became chronically ill and exhibited no symptoms during the period of observation which, for certain birds, lasted more than 6 months. There was no indication that the parasites were in any way modified by such prolonged exposure to conditions in the avian host, except where chicks were experimentally employed. In the latter case, there was a definite indication of lessened virulence after twenty serial passages.Grackles with experimental infections exhibited an easily demonstrable parasitemia for at least as long as 5 days, during which as little as 0.1 ml of their blood was infective to mice.Two young pigeons, fed for 2 weeks by a mother with an acute case of toxoplasmosis, failed to become infected, but proved susceptible when later inoculated with parasites. They developed a chronic infection, characterized by a rise of antibodies in much the same fashion as in mammals having the disease. The antibody curve remained high for the entire period of observation (6 months).Mouse brains from experimentally induced cases of toxoplasmosis remained infective for as long as 18 days when stored in an ordinary electric refrigerator and immersed in sterile Difco skim milk. Exposure to higher temperatures however showed that 55 °C for 5 minutes is lethal to the parasite, and that in some cases they are no longer viable after an exposure of equal duration to 50 °C. 相似文献
3.
Thomas E. Besser E. Frances Cassirer Amy Lisk Danielle Nelson Kezia R. Manlove Paul C. Cross John T. Hogg 《Ecology and evolution》2021,11(21):14366
A respiratory disease epizootic at the National Bison Range (NBR) in Montana in 2016–2017 caused an 85% decline in the bighorn sheep population, documented by observations of its unmarked but individually identifiable members, the subjects of an ongoing long‐term study. The index case was likely one of a small group of young bighorn sheep on a short‐term exploratory foray in early summer of 2016. Disease subsequently spread through the population, with peak mortality in September and October and continuing signs of respiratory disease and sporadic mortality of all age classes through early July 2017. Body condition scores and clinical signs suggested that the disease affected ewe groups before rams, although by the end of the epizootic, ram mortality (90% of 71) exceeded ewe mortality (79% of 84). Microbiological sampling 10 years to 3 months prior to the epizootic had documented no evidence of infection or exposure to Mycoplasma ovipneumoniae at NBR, but during the epizootic, a single genetic strain of M. ovipneumoniae was detected in affected animals. Retrospective screening of domestic sheep flocks near the NBR identified the same genetic strain in one flock, presumptively the source of the epizootic infection. Evidence of fatal lamb pneumonia was observed during the first two lambing seasons following the epizootic but was absent during the third season following the death of the last identified M. ovipneumoniae carrier ewe. Monitoring of life‐history traits prior to the epizootic provided no evidence that environmentally and/or demographically induced nutritional or other stress contributed to the epizootic. Furthermore, the epizootic occurred despite proactive management actions undertaken to reduce risk of disease and increase resilience in this population. This closely observed bighorn sheep epizootic uniquely illustrates the natural history of the disease including the (presumptive) source of spillover, course, severity, and eventual pathogen clearance. 相似文献
4.
G V Kornilova M I Ra?khlin V K Iastrebov M S Sha?man L S Egorova 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1975,(11):96-100
New materials are presented on the presence of the foci of anthropozoonozes in the Extreme North. For the first time there was established the existence in the subarctic tundra of the Taimyr peninsula of the arbovirus foci of the tick-borne encephalitis complex. A virus of the tick-borne encephalitis complex was isolated in 1973 from the gamasida ticks Haemogamasus ambulans Thorel. and Hirstionyssus isabellinus Oudms. and the nests of the Siberian lemming Lemmus lemmus L. This pointed to the existence in the Transpolar region of the foci or arboviruses in the nest-hole biocenoses of the lemmings outside the bird colonies. Cultures of tularemia bacilli (which proved the etiology of the epizootic among the lemmings observed in 1973 and also the presence of the lemming natural foci of tularemia and their combination with the arbovirus foci) were isolated from the lemmings at the same territory. The results of serological examination of the local population and of the animals pointed to the circulation in the Transpolar region of the causative agents of leptospirosis, toxoplasmosis, Q-fever and of the Asian tick-borne rickettsiosis. 相似文献
5.
T M John B Pilo J C George C G Scanes 《Archives internationales de physiologie et de biochimie》1985,93(3):249-253
Plasma levels of growth hormone (GH), free fatty acids (FFA) and glucose were measured in vagotomized (VgX) and sham-operated (VgS) control pigeons. In VgX pigeons, GH level was significantly lower whereas FFA and glucose levels were higher than in VgS pigeons. The depression in GH level in VgX pigeons has been attributed to the significantly high levels of norepinephrine (NE) and corticosterone in these Birds. The higher plasma FFA concentration in VgX pigeons was therefore due to adipokinetic hormonal action other than of GH. It has been suggested that the adrenocorticotrophic hormone (ACTH) and/or NE could have produced the increase in plasma FFA in VgX pigeons. The pronounced hyperglycemia seen in VgX pigeons has been attributed to catecholamine action in the absence of the vagal tone. 相似文献
6.
Nina Hedlund Markussen 《Ecography》1992,15(1):111-113
From 1986-90 we tagged 98 harbour seal pups at Hvaler, Norway Fifteen were recovered later the same year of which 10 were recovered in 1988, when the seal population was infected by a morbillivirus The epizootic in 1988 resulted in a population decline of c 75% Predicted birth weight did not vary significantly before and after the epizootic Newborn harbour seals have antibodies against the morbillivirus two years after the outbreak of the disease 相似文献
7.
We assessed land use and demographic data as predictors discriminating between counties experiencing large or small first epizootics of rabies among raccoons (Procyon lotor). Monthly county reports of raccoons testing positive for rabies were obtained from rabies surveillance databases from Maryland, Pennsylvania, and Virginia (USA). Environmental and demographic data for the three states were obtained from public sources. On the basis of total reports of raccoon rabies during the first defined epizootic period, the 203 counties were dichotomized at the 75th percentile as having a large epizootic (> or = 24 rabid raccoons in the first epizootic) (51 counties) or a small epizootic or no epizootic (152 counties). A high percentage of agricultural land use [OR = 9.1, 95% CI (3.6-23.1)], high water coverage in combination with low human population density [OR = 8.8, 95% CI (2.9-27.0)], and low water coverage with high human population density [OR = 11.7, 95% CI (4.0-34.1)] were positively associated with large rabies epizootics. Counties with more than 15% of mixed forest were less likely to experience large epizootics than were counties with < or = 15% of mixed forest [OR = 0.3, 95% CI (0.1, 0.9)]. A combination of land use and human population density measures provided the best model for determining epizootic size and may be important predictors of epizootic behavior and risk of exposure to this reservoir species. 相似文献
8.
HJ Ahn PY Cho SK Ahn TS Kim CK Chong SJ Hong SH Cha HW Nam 《The Korean journal of parasitology》2012,50(3):225-227
The seroepidemiological status of toxoplasmosis was surveyed among the residents of Cheorwon-gun, Gangwon-do by means of ELISA using a crude extract antigen of Toxoplasma gondii. The sera of 1,661 adult residents (866 males and 795 females) were collected and checked for IgG antibody titers, which showed 17.0% positive rate (282 sera). The positive rate was significantly different between the sex; 20.6% for males and 13.1% for females (P<0.05). The positive rates were higher in fifties of males (28.7%) and forties of females (20.0%). This positive rate of toxoplasmosis in Cheorwon-gun residents is regarded as the highest among the surveys of different geographical regions of Korea. This high positive rate may due in part to peculiar geographical locality of the surveyed area near the naturally well preserved demilitarized zone (DMZ) or presumably consumption of the pork imported from high endemic nations. Therefore, it is necessary to study further the epidemiology of toxoplasmosis in Cheorwon-gun. 相似文献
9.
Vector infection determinants of Venezuelan equine encephalitis virus reside within the E2 envelope glycoprotein
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Epizootic subtype IAB and IC Venezuelan equine encephalitis viruses (VEEV) readily infect the epizootic mosquito vector Aedes taeniorhynchus. The inability of enzootic subtype IE viruses to infect this mosquito species provides a model system for the identification of natural viral determinants of vector infectivity. To map mosquito infection determinants, reciprocal chimeric viruses generated from epizootic subtype IAB and enzootic IE VEEV were tested for mosquito infectivity. Chimeras containing the IAB epizootic structural gene region and, more specifically, the IAB PE2 envelope glycoprotein E2 precursor gene demonstrated an efficient infection phenotype. Introduction of the PE2 gene from an enzootic subtype ID virus into an epizootic IAB or IC genetic backbone resulted in lower infection rates than those of the epizootic parent. The finding that the E2 envelope glycoprotein, the site of epitopes that define the enzootic and epizootic subtypes, also encodes mosquito infection determinants suggests that selection for efficient infection of epizootic mosquito vectors may mediate VEE emergence. 相似文献
10.
J. Cerella [Pattern Recognit. 12 (1980) 1] and more recently S. Watanabe [Behav. Proc. 53 (2001) 3] demonstrated that pigeons showed no decrement in recognizing cartoons that were spatially scrambled, indicating that pigeons' discriminative responding is controlled by local features alone. In contrast Kirkpatrick-Steger et al. [J. Exp. Psychol. Anim. Behav. Proc. 24 (1998) 34] used line drawings as stimuli and demonstrated the importance of spatial organization for picture recognition by pigeons, confirming related findings reported in their previous studies. The present study revisited the recognition of cartoons by pigeons. In Experiment 1, pigeons were trained to discriminate cartoon people on a variety of background scenes. Subsequent tests revealed that discriminative performances with both familiar and novel instances decreased as the objects and object-like parts were progressively fragmented, indicating that search for the targeted cartoon people in the stimulus array might have enhanced the pigeons to attend to global aspects of cartoon people. Experiment 2 used line drawings of cartoon faces as stimuli and examined effects of scrambling and deletion of components. A set of components (eyes and eyebrows) exerted strong control over behavior and scrambling only moderately suppressed responding. The results suggest that pigeons use both global and local aspects, with different mixtures of these types of information depending on the particular perceptual context. 相似文献
11.
P A Webb R G McLean G C Smith J H Ellenberger D B Francy T E Walton T P Monath 《Journal of wildlife diseases》1987,23(2):192-198
Sera obtained from wild ungulates, carnivores, and rodents in Colorado were tested for neutralizing (N) antibody against vesicular stomatitis, New Jersey serotype (VSNJ), virus to determine their involvement in the 1982 Colorado VSNJ epizootic in domestic animals. Viremic and N antibody responses of two local rodent species to a 1982 Colorado isolate of VSNJ were determined in the laboratory. The rodents produced only weak viremias, but all developed N antibody. N antibody prevalences for VSNJ in sera from wild ungulates was sufficiently high to indicate their involvement during the epizootic. In addition, the demonstration of N antibody in elk (Cervus elaphus) and mule deer (Odocoileus hemionus) prior to the epizootic in cattle and horses suggests that an enzootic cycle may exist in Colorado. 相似文献
12.
CINO PERTOLDI MICHELA PODESTÁ VOLKER LOESCHCKE SØREN SCHANDORFF LETIZIA MARSILI CECILIA MANCUSI PAOLA NICOLOSI ETTORE RANDI 《Biological journal of the Linnean Society. Linnean Society of London》2000,71(1):61-70
Developmental stability of the community of striped dolphins, Stenella coeruleoalba (Meyen, 1833), that died during the Mediterranean epizootic of 1990 was compared with that of the population prior to and after the epizootic, to assess whether animals that died were the developmentally less stable individuals in the population. Significantly higher levels of fluctuating asymmetry (FA) were found in those individuals that died. Tissue levels of organochlorine pesticide residues and PCBs were determined and the correlation between contaminant concentration and FA was tested. No correlations were found between the contaminant level and FA. 相似文献
13.
Intestinal carriage of campylobacters, salmonellas, yersinias and listerias in pigeons in the city of Barcelona 总被引:1,自引:1,他引:0
L. Casanovas M. de Simón M.D. Ferrer J. Arqués G. Monzón 《Journal of applied microbiology》1995,78(1):11-13
L. CASANOVAS, M. DE SIMÓN, M.D. FERRER, J. ARQUÉS AND G. MONZÓN. 1995. The faecal bacterial flora of pigeons, which may be the source of infectious diseases in man, was studied in the city of Barcelona. Four hundred cloacal specimens were examined for Campylobacter jejuni, Camp. coli, Salmonella spp., Yersinia spp. and Listeria spp., over a 12 month period.
Campylobacter jejuni was the most frequently isolated micro-organism, found in 105 pigeons (26.2%), with a greater incidence in the districts of the city with a high density of pigeons and without seasonal variation. Salmonella spp. were isolated from six specimens (1.5%) and Yersinia intermedia was isolated from only one pigeon. 相似文献
Campylobacter jejuni was the most frequently isolated micro-organism, found in 105 pigeons (26.2%), with a greater incidence in the districts of the city with a high density of pigeons and without seasonal variation. Salmonella spp. were isolated from six specimens (1.5%) and Yersinia intermedia was isolated from only one pigeon. 相似文献
14.
Six pigeons were trained first on a color then on a form discrimination; four other pigeons were trained first on form and then on color. One of two colors or one of two forms (sample stimuli) appeared in the center of a touch sensitive monitor for 5 pigeons and in the center and in 16 other locations for 5 other pigeons. A peck anywhere within the region in which the sample stimuli appeared produced two white disks (comparison stimuli), one on the left and one on the lower right corners of the screen. Correct left-right choices provided food. Although of no consequence, the location of pecks in presence of the sample was predictive of the pigeon's subsequent choice. Accuracy, choice of the correct comparison stimulus, was greater when the sample stimuli appeared in the center as well as 16 other locations than when it appeared only in the center. The presolution period, the period of chance accuracy prior to evidence of discrimination learning, was decreased on each task following training on the other task. This evidence of facilitation following an extra-dimensional shift was attributed to continued relevance of the conditions under which the first task was learned. The duration of the presolution period was inversely related to asymptotic accuracy-data accounted for by Heinemann's (1983) theory of information processing during the presolution period. 相似文献
15.
Epizootic potential for aphids of different isolates of the fungus,Verticillium lecanii 总被引:1,自引:0,他引:1
R. A. Hall 《BioControl》1984,29(3):311-321
Large (6.7–8.4 μm in length) and small (3.8–6.7 μm in length) spored strains ofVerticillium lecanii (Zimm) Viégas killed similar numbers of adults of the aphids treated with aqueous spore suspensions. However, when these strains were compared by determining the proportions of progeny aphids acquiring infection from treated adults, i.e. a measure of epizootic potential, large differences emerged; only large-spored strains exhibited as strong an epizootic potential as the standard strain, 1–72, with mean progeny mortality ratios (test/standard) close to 1.0. Further experiments indicated that the speed of germination, fastest for large-spored strains, accounted for the greater epizootic potential of such strains. In addition, the mode of sporulation of large-spored strains on aphid cadavers probably also contributed to the more efficient spread of such strains. A general conclusion was reached that measurement of the effectiveness of a pathogen against a host insect must be based on many factors, in addition to virulence against a single developmental stage. 相似文献
16.
Surveillance for sylvatic plague (Yersinia pestis) was conducted near Meeteetse, Wyoming (USA) from 24 May to 14 June 1985. Ten species of fleas were collected from white-tailed prairie dogs (Cynomys leucurus), and from their burrows and associated rodents. Five of these flea species and two adult prairie dogs were positive for plague. The progression of this plague epizootic appeared to be slower and the intensity was less than in previous epizootics in other prairie dog colonies. The plague epizootic occurred within the only known colony of black-footed ferrets (Mustela nigripes) and was a potential threat to the food source of this endangered species. 相似文献
17.
Seymore Herling David W. Hein Mary A. Nemeth Rita J. Valentino James H. Woods 《Life sciences》1982,30(4):331-341
The discriminative effects of cyclorphan were studied in pigeons trained to discriminate 0.32 mg/kg ethylketazocine, 1.8 mg/kg cyclazocine, or 32 mg/kg naltrexone from saline. A fourth group of pigeons was administered 100 mg/kg/day morphine and trained to discriminate 0.1 mg/kg naltrexone from saline. Cyclorphan produced dose-related ethylketazocine-appropriate responding that reached a maximum of 83% of the total session responses at 0.3 mg/kg. Higher cyclorphan doses produced less ethylketazocine-appropriate responding. In pigeons trained to discriminate cyclazocine from saline, maximum drug-appropriate responding of greater than 90% occured at 5.6–10.0 mg/kg cyclorphan. In narcotic-naive pigeons trained to discriminate 32 mg/kg naltrexone from saline, cyclorphan produced a maximum of less than 50% drug-appropriate responding. In contrast, in pigeons chronically administered morphine and trained to discriminate 0.1 mg/kg naltrexone from saline, 1.0 mg/kg cyclorphan resulted in 100% drug-appropriate responding. In pigeons responding under a multiple fixed-interval, fixed-ratio schedule of food delivery, cyclorphan produced a complete dose-related reversal of the rate-decreasing effects of 10 mg/kg morphine, the maximally effective antagonist doses being 1.0–3.2 mg/kg. Higher cyclorphan doses (10 mg/kg) resulted in response rate decreases that were not reversed by naloxone (1 mg/kg). Thus, cyclorphan has discriminative effects that are similar to those of both ethylketazocine and, at 20-fold higher doses, cyclazocine. In addition, in morphine-treated pigeons, cyclorphan, across the same range of doses that produce ethylketazocine-appropriate responding, has discriminative effects that are similar to those of naltrexone, an effect that is probably related to the antagonist action of the drug. 相似文献
18.
Hong SJ Chong CK Lee K Kim TS Hong YP Ahn HJ Kim HY Ko AR Kim YJ Nam HW 《The Korean journal of parasitology》2011,49(3):309-311
Seroepidemiological status of toxoplasmosis among the residents of Jeju island was surveyed and evaluated by ELISA with crude extract of Toxoplasma gondii. The sera of 2,348 residents (male 1,157 and female 1,191) were collected and checked for the IgG antibody titers, which showed 13.2% positive rate (309 sera). The positive rates were increasing gradually according to the age from 4.3% in teenage to 20.6% in seventies. The positive rates were significantly different between the sex by 16.2% for male and 10.2% for female (P<0.05). This positive rate of toxoplasmosis in Jeju island residents is regarded relatively higher than any other regions of Korea. And the high positive rate may be maintained continuously among Jeju island residents without any clear reasons until now but due to some parts peculiar socio-cultural tradition of Jeju island. Therefore, it is necessary to study further the epidemiology of toxoplasmosis of Jeju island. 相似文献
19.
Jihye Yu Woojin Kim Yoon Kyung Chang Tong-Soo Kim Sung-Jong Hong Hye-Jin Ahn Ho-Woo Nam Dongjae Kim 《The Korean journal of parasitology》2021,59(3):251
We find out the clusters with high toxoplasmosis risk to discuss the geographical pattern in Gyodong-myeon and Samsan-myeon of Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea. Seroepidemiological data of toxoplasmosis surveyed using rapid diagnostic tests for the residents in the areas in 2019 were analyzed to detect clusters of the infection. The cluster was investigated using the SaTScan program which is based on Kulldorff’s scan statistic. The clusters were found with P-values in each region analyzed in the program, and the risk and patient incidence of specific areas can be examined by the values such as relative risk and log likelihood ratio. Jiseok-ri and Insa-ri were found to be a cluster in Gyodong-myeon and Seokmo-ri was the cluster in Samsan-myeon. Yangji-ri and Igil-ri were found to be a cluster in Cheorwon-gun and Madal-ri and Baebong-ri were the cluster in Goseong-gun. This findings can be used to monitor and prevent toxoplasmosis infections occurring in vulnerable areas. 相似文献